Gene Symbol | LAMB1 |
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Entrez Gene | 3912 |
Alt Symbol | CLM, LIS5 |
Species | Human |
Gene Type | protein-coding |
Description | laminin, beta 1 |
Other Description | laminin B1 chain|laminin subunit beta-1 |
Swissprots | Q14D91 P07942 |
Accessions | AAA59485 AAA59486 AAS07514 CCQ43174 EAL24388 EAW83423 EAW83424 P07942 AK303501 BAG64534 AK307611 AK309921 BC026018 AAH26018 BC044633 BC052598 BC113455 AAI13456 BX648251 DA861108 M20206 AAA59487 M61916 AAA59482 XM_011516203 XP_011514505 NM_002291 NP_002282 |
Function | Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface. {ECO:0000269|PubMed:23472759}. |
Subcellular Location | Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component. |
Top Pathways | Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Toxoplasmosis |
LAMB1 / Laminin Beta 1 Antibody Blocking Peptide - LS-E2862 from LifeSpan Bioscience
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LAMB1 / Laminin Beta 1 Antibody Blocking Peptide - LS-E17569 from LifeSpan Bioscience
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LAMB1-Antibody-C-term-Blocking-peptide - BP13983b from Abgent, a WuXi AppTec company
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Recombinant human Laminin subunit beta-1 protein (OPCA01021) - OPCA01021 from Aviva Systems Biology
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Human LAMB1 protein - orb245584 from Biorbyt
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LAMB1 protein - 30R-3284 from Fitzgerald
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LAMB1 fusion protein - ag19182 from Proteintech Group
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CST9 Human - PRPS-962 from NeoScientific
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Recombinant Human LAMB1, His-tagged - LAMB1-29912TH from Creative Biomart
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Recombinant Laminin Beta 1 (LAMb1) - RPA184Hu01 from Uscn Life Science Inc.
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Recombinant Laminin Beta 1 (LAMb1) - RPA184Mu01 from Uscn Life Science Inc.
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Laminin, mouse purified - CC095 from EMD Millipore
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Human Laminin (pepsinized) Purified Protein - AG56P from EMD Millipore
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Laminin beta 1 Blocking Peptide - CBP4055 from Cohesion Biosciences
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Laminin β-1 (D1742) Peptide - BS2415P from Bioworld Technology
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Recombinant Laminin Beta 1 (LAMb1) - RPA184Hu01 from Cloud-clone
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Recombinant human Laminin subunit beta-1 protein - CSB-EP142974h CSB-BP142974h CSB-MP142974h from Cusabio
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Recombinant Human Laminin subunit beta-1(LAMB1),partial - CSB-RP142974h from Cusabio
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Recombinant Human Laminin subunit beta-1(LAMB1) ,partial - CSB-YP012730HU CSB-EP012730HU CSB-BP012730HU CSB-MP012730HU from Cusabio
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Laminin beta 1 Recombinant Protein Antigen - NBP1-88074PEP from Novus Biologicals
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Laminin beta 1 Recombinant Protein Antigen - NBP1-88073PEP from Novus Biologicals
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Laminin beta 1 Blocking Peptide - abx162548 from Abbexa
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Recombinant human Laminin subunit beta-1 protein - AP72243 from Signalway Antibody
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LAMB1, Recombinant Protein - MBS5303828 from MyBioSource
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Laminin subunit beta-1, Recombinant Protein - MBS954494 from MyBioSource
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