LAMB1

Gene Symbol LAMB1
Entrez Gene 3912
Alt Symbol CLM, LIS5
Species Human
Gene Type protein-coding
Description laminin, beta 1
Other Description laminin B1 chain|laminin subunit beta-1
Swissprots Q14D91 P07942
Accessions AAA59485 AAA59486 AAS07514 CCQ43174 EAL24388 EAW83423 EAW83424 P07942 AK303501 BAG64534 AK307611 AK309921 BC026018 AAH26018 BC044633 BC052598 BC113455 AAI13456 BX648251 DA861108 M20206 AAA59487 M61916 AAA59482 XM_011516203 XP_011514505 NM_002291 NP_002282
Function Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components. Involved in the organization of the laminar architecture of cerebral cortex. It is probably required for the integrity of the basement membrane/glia limitans that serves as an anchor point for the endfeet of radial glial cells and as a physical barrier to migrating neurons. Radial glial cells play a central role in cerebral cortical development, where they act both as the proliferative unit of the cerebral cortex and a scaffold for neurons migrating toward the pial surface. {ECO:0000269|PubMed:23472759}.
Subcellular Location Secreted, extracellular space, extracellular matrix, basement membrane. Note=Major component.
Top Pathways Focal adhesion, ECM-receptor interaction, Small cell lung cancer, Amoebiasis, Toxoplasmosis

Laminin β-1 (3A4) - sc-65644 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal

Laminin β-1 (A-1) - sc-17810 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Laminin β-1 (A-1): sc-17810. IImmunofluorescence staining of normal mouse eye frozen section showing basement membrane and trabecular meshwork staining.

Laminin β-1 (C-19) - sc-6018 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Laminin β-1 (C-19): sc-6018. Western blot analysis of Laminin β-1 expression in NIH/3T3 whole cell lysate (A) and in rat kidney extract (B).

Laminin β-1 (D-15) - sc-23410 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Laminin β-1 (D-9) - sc-17763 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Laminin β-1 (D-9): sc-17763. Immunoperoxidase staining of formalin fixed, paraffin-embedded human thyroid gland tissue showing extracellular staining around glandular cells. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Laminin β-1 (H-300) - sc-5583 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Laminin β-1 (H-300): sc-5583. Western blot analysis of Laminin β-1 expression in A-431 whole cell lysate.

Laminin β-1 (L-18) - sc-23411 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Laminin β-1 (LT3) - sc-33709 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rat
Clonality Monoclonal
Laminin β-1 (LT3): sc-33709. Immunofluorescence staining of normal mouse eye frozen section showing basement membrane, Descemets membrane and smooth muscle staining.

Anti-Laminin beta 1 antibody - ab69633 from Abcam

Prices $384.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Laminin beta 1 antibody (ab69633) at 1/500 dilutionLane 1 : Extracts from HepG2 cellsLane 2 : Extracts from HepG2 cells with immunising peptide at 5 µgLysates/proteins at 5 µg per lane.

Anti-Laminin beta 1 antibody - ab98232 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Laminin beta 1 antibody (ab98232) at 1 µg/ml (in 5% skim milk / PBS buffer) + Human fetal stomach lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Laminin beta 1 antibody [2D9G5] - ab130204 from Abcam

Host Mouse
Clonality Monoclonal
Clone 2D9G5
Anti-Laminin beta 1 antibody [2D9G5] (ab130204) at 1/500 dilution + Truncated Laminin beta 1-His recombinant protein

Anti-Laminin beta 1 antibody [DG10] - ab88279 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone DG10

Anti-Laminin beta 1 antibody [EPR3189(2)] - ab108536 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3189(2)
All lanes : Anti-Laminin beta 1 antibody [EPR3189(2)] (ab108536) at 1/1000 dilutionLane 1 : JAR cell lysateLane 2 : A431 cell lysateLane 3 : SW480 cell lysateLane 4 : 293T cell lysateLane 5 : C6 cell lysateLysates/proteins at 10 µg per lane.

Anti-Laminin beta 1 antibody [EPR3190(2)] - ab109293 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3190(2)
All lanes : Anti-Laminin beta 1 antibody [EPR3190(2)] (ab109293) at 1/1000 dilutionLane 1 : Human fetal kidney lysateLane 2 : A431 lysateLysates/proteins at 10 µg per lane.

Anti-Laminin beta 1 antibody [LT3] - ab44941 from Abcam

Prices $388.00
Sizes 250 µl
Host Rat
Clonality Monoclonal
Clone LT3
ICC/IF image of ab44941 staining human prostate cells.  The cells were fixed with 4% paraformaldehyde, permeabilised with 0.8% Triton X-100, and blocked with 20% serum for 1 hour at 24°C.  The primary anitibody was diluted 1/400 in in 20% horse serum in PBS and incubated for 20 minutes at 4°C.  An Alexa Fluor® 488 conjugated donkey anti-rat was used as the secondary antibody.The blue staining is the cell nuclei, the green staining shows the laminin beta 1.See Abreview

Anti-Laminin beta 1 antibody [LT3] (Biotin) - ab79671 from Abcam

Prices $378.00
Sizes 250 µl
Host Rat
Clonality Monoclonal
Clone LT3

Anti-Laminin beta 1 antibody [SPM276], prediluted - ab54271 from Abcam

Host Rat
Clonality Monoclonal
Clone SPM276

Anti-LAMB1 / Laminin Beta 1 Antibody (C-Terminus) - LS-C122054 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LAMB1 / Laminin Beta 1 Antibody (clone DG10) - LS-C123968 from LifeSpan Bioscience

Prices $650.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone DG10

Anti-LAMB1 / Laminin Beta 1 Antibody (aa570-586, Magnetic beads) - LS-C171770 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LAMB1 / Laminin Beta 1 Antibody (aa570-586, Sepharose) - LS-C171771 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LAMB1 / Laminin Beta 1 Antibody - LS-C190980 from LifeSpan Bioscience

Prices $405.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-LAMB1 / Laminin Beta 1 Antibody (Internal, clone EPR3189(2)) - LS-C138351 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR3189(2)
Western blot analysis on (A) JAR, (B) A431, (C) SW480, (D) 293T, and (E) C6 cell lysates using anti-Laminin Beta 1 antibody.

Anti-LAMB1 / Laminin Beta 1 Antibody (clone GF1) - LS-C190219 from LifeSpan Bioscience

Prices $530.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone GF1

Anti-LAMB1 / Laminin Beta 1 Antibody (clone DG10) - LS-C202512 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone DG10
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