Gene Symbol | P3h1 |
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Entrez Gene | 56401 |
Alt Symbol | 2410024C15Rik, Gros1, Lepre1 |
Species | Mouse |
Gene Type | protein-coding |
Description | prolyl 3-hydroxylase 1 |
Other Description | growth suppressor 1|leprecan 1|leprecan-1|leucine- and proline-enriched proteoglycan 1 |
Swissprots | Q8BSV2 A6PW85 Q8CFL3 Q3V1T4 Q9CWK5 Q9QZT6 Q9QZT7 Q3TWX8 A2A7Q4 |
Accessions | EDL30456 EDL30457 EDL30458 Q3V1T4 AF165163 AAF04806 AF165164 AAF04807 AK010578 BAB27041 AK030436 BAC26962 AK132262 BAE21065 AK159505 BAE35138 AK165077 AK183740 AK187865 AK193263 AK214845 AK217893 BB617770 BC024047 AAH24047 BY240019 CO040878 CX563255 NM_001042411 NP_001035874 NM_001286148 NP_001273077 NM_019782 NP_062756 NM_019783 NP_062757 |
Function | Basement membrane-associated chondroitin sulfate proteoglycan (CSPG). Has prolyl 3-hydroxylase activity catalyzing the post-translational formation of 3-hydroxyproline in -Xaa-Pro- Gly- sequences in collagens, especially types IV and V. May be involved in the secretory pathway of cells. Has growth suppressive activity in fibroblasts (By similarity). {ECO:0000250}. |
Subcellular Location | Endoplasmic reticulum {ECO:0000255|PROSITE- ProRule:PRU10138}. Secreted, extracellular space, extracellular matrix {ECO:0000250}. Note=Secreted into the extracellular matrix as a chondroitin sulfate proteoglycan (CSPG). |
Recombinant Mouse Prolyl 3-hydroxylase 1(Lepre1) - CSB-YP666301MO CSB-EP666301MO CSB-BP666301MO CSB-MP666301MO from Cusabio
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Prolyl 3-hydroxylase 1 (Lepre1), Recombinant Protein - MBS1464647 from MyBioSource
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Recombinant Mouse LEPRE1 Protein - LEPRE1-9050M from Creative Biomart
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