Gene Symbol | LRRC17 |
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Entrez Gene | 10234 |
Alt Symbol | P37NB |
Species | Human |
Gene Type | protein-coding |
Description | leucine rich repeat containing 17 |
Other Description | 37 kDa leucine-rich repeat (LRR) protein|leucine-rich repeat-containing protein 17 |
Swissprots | Q13288 Q6UWA7 Q8N6Y2 Q75MG5 |
Accessions | AAS07483 EAW83307 EAW83308 Q8N6Y2 AI961444 AK225701 AK226021 AK290305 BAF82994 AY358889 AAQ89248 BC027903 AAH27903 DA749917 EU832314 ACE87571 EU832399 ACE86884 U32907 AAB41565 XM_005250108 XP_005250165 NM_001031692 NP_001026862 NM_005824 NP_005815 |
Function | Involved in bone homeostasis. Acts as a negative regulator of RANKL-induced osteoclast precursor differentiation from bone marrow precursors (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted, extracellular space {ECO:0000250}. |
Tissue Specificity | Expressed in osteoblast cell lines. Well expressed in ovary, heart, pancreas, skeletal muscle, lung, and fetal kidney and lung and only at the basal levels in the other tissues examined including adult kidney. More expressed in S-type neuroblastoma cells than in N-type neuroblastoma cells. {ECO:0000269|PubMed:19336404, ECO:0000269|PubMed:8982252}. |
Human LRRC17 full length protein - ab160894 from Abcam
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LRRC17 Antibody Blocking Peptide - LS-E18600 from LifeSpan Bioscience
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Recombinant Human LRRC17 Protein - H00010234-P01 from Novus Biologicals
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LRRC17 Blocking Peptide - 33R-10275 from Fitzgerald
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LRRC17 - H00010234-P01-10 from Acris Antibodies
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LRRC17 - H00010234-P01-25 from Acris Antibodies
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LRRC17 fusion protein - ag15117 from Proteintech Group
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LRRC17 fusion protein - ag15259 from Proteintech Group
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Recombinant Human LRRC17, GST-tagged - LRRC17-83H from Creative Biomart
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Recombinant Human Leucine-rich repeat-containing protein 17(LRRC17) - CSB-YP818720HU CSB-EP818720HU CSB-BP818720HU CSB-MP818720HU from Cusabio
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LRRC17 (full length, N-term HIS tag, transcript variant 2) - TP760583 from Acris Antibodies
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LRRC17 Protein - NBP1-83309PEP from Novus Biologicals
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LRC17-Antibody-C-term-Blocking-Peptide - BP9419b from Abgent, a WuXi AppTec company
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LRRC17 Peptide, Human - M34GP08876H from Creative Peptides
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Leucine-rich repeat-containing protein 17 (LRRC17), Recombinant Protein - MBS1428174 from MyBioSource
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