Gene Symbol | ELOVL3 |
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Entrez Gene | 83401 |
Alt Symbol | CIG-30, CIG30 |
Species | Human |
Gene Type | protein-coding |
Description | ELOVL fatty acid elongase 3 |
Other Description | 3-keto acyl-CoA synthase ELOVL3|ELOVL FA elongase 3|cold-inducible glycoprotein of 30 kDa|elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3|elongation of very long chain fatty acids protein 3|very-long-chain 3-oxoacyl-CoA synthase 3 |
Swissprots | Q9HB03 Q5VZL3 Q8N180 |
Accessions | AAG17875 EAW49711 Q9HB03 BC034344 AAH34344 HQ447376 ADQ31862 HY050356 XM_011540245 XP_011538547 NM_152310 NP_689523 |
Function | Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. {ECO:0000269|PubMed:20937905}. |
Subcellular Location | Endoplasmic reticulum membrane {ECO:0000269|PubMed:20937905}; Multi-pass membrane protein {ECO:0000255}. |
Tissue Specificity | Testis. {ECO:0000269|PubMed:20937905}. |
Top Pathways | Fatty acid elongation |
ELOVL3 (G-15) - sc-54876 from Santa Cruz Biotechnology
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ELOVL3 (N-17) - sc-54878 from Santa Cruz Biotechnology
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Anti-Elongation of very long chain fatty acids protein 3 antibody - ab110872 from Abcam
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Anti-Elongation of very long chain fatty acids protein 3 antibody - C-terminal - ab156071 from Abcam
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Anti-ELOVL3 Antibody (aa241-270, AP) - LS-C213768 from LifeSpan Bioscience
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Anti-ELOVL3 Antibody (aa241-270, APC) - LS-C213769 from LifeSpan Bioscience
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Anti-ELOVL3 Antibody (aa241-270, FITC) - LS-C213773 from LifeSpan Bioscience
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Anti-ELOVL3 Antibody (aa241-270, Biotin) - LS-C213771 from LifeSpan Bioscience
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Anti-ELOVL3 Antibody (aa241-270, PE) - LS-C213775 from LifeSpan Bioscience
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Anti-ELOVL3 Antibody (aa241-270, Azide-free, HRP) - LS-C213774 from LifeSpan Bioscience
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Anti-ELOVL3 Antibody (aa240-270) - LS-C321096 from LifeSpan Bioscience
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Anti-ELOVL3 Antibody (aa31-80) - LS-C119952 from LifeSpan Bioscience
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Anti-ELOVL3 Antibody (aa241-270) - LS-C157711 from LifeSpan Bioscience
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ELOVL3 Antibody - NBP1-85618 from Novus Biologicals
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Anti-ELOVL3 antibody produced in rabbit - HPA036236 from Sigma-Aldrich
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ELOVL3-AntibodyC-term - AP19871b from Abgent, a WuXi AppTec company
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ELOVL3 antibody - GTX87195 from GeneTex
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ELOVL3 Antibody - C-terminal region (OAAB15332) - OAAB15332 from Aviva Systems Biology
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ELOVL3 Antibody (OAAF03637) - OAAF03637 from Aviva Systems Biology
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ELOVL3 antibody - orb160897 from Biorbyt
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Anti -ELOVL3, CT (ELOVL3, CIG30, Elongation of very long chain fatty acids protein 3,3-keto acyl-CoA synthase ELOVL3, Cold-inducible glycoprotein of 30kD, ELOVL fatty acidelongase 3) - 035049 from USBiological Life Science
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Anti -ELOVL3, CT (ELOVL3, CIG30, Elongation of very long chain fatty acids protein 3,3-keto acyl-CoA synthase ELOVL3, Cold-inducible glycoprotein of 30kD, ELOVL fatty acidelongase 3) (AP) - 035049-AP from USBiological Life Science
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Anti -ELOVL3, CT (ELOVL3, CIG30, Elongation of very long chain fatty acids protein 3,3-keto acyl-CoA synthase ELOVL3, Cold-inducible glycoprotein of 30kD, ELOVL fatty acidelongase 3) (APC) - 035049-APC from USBiological Life Science
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Anti -ELOVL3, CT (ELOVL3, CIG30, Elongation of very long chain fatty acids protein 3,3-keto acyl-CoA synthase ELOVL3, Cold-inducible glycoprotein of 30kD, ELOVL fatty acidelongase 3) (Azide free) (HRP) - 035049-HRP from USBiological Life Science
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Anti -ELOVL3, CT (ELOVL3, CIG30, Elongation of very long chain fatty acids protein 3,3-keto acyl-CoA synthase ELOVL3, Cold-inducible glycoprotein of 30kD, ELOVL fatty acidelongase 3) (Biotin) - 035049-Biotin from USBiological Life Science
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