ELOVL3

Gene Symbol	ELOVL3
Entrez Gene	83401
Alt Symbol	CIG-30, CIG30
Species	Human
Gene Type	protein-coding
Description	ELOVL fatty acid elongase 3
Other Description	3-keto acyl-CoA synthase ELOVL3|ELOVL FA elongase 3|cold-inducible glycoprotein of 30 kDa|elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 3|elongation of very long chain fatty acids protein 3|very-long-chain 3-oxoacyl-CoA synthase 3
Swissprots	Q9HB03 Q5VZL3 Q8N180
Accessions	AAG17875 EAW49711 Q9HB03 BC034344 AAH34344 HQ447376 ADQ31862 HY050356 XM_011540245 XP_011538547 NM_152310 NP_689523
Function	Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme with higher activity toward C18 acyl-CoAs, especially C18:0 acyl-CoAs. May participate to the production of saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. {ECO:0000269|PubMed:20937905}.
Subcellular Location	Endoplasmic reticulum membrane {ECO:0000269|PubMed:20937905}; Multi-pass membrane protein {ECO:0000255}.
Tissue Specificity	Testis. {ECO:0000269|PubMed:20937905}.
Top Pathways	Fatty acid elongation

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

ELOVL3 CRISPR/Cas9 KO Plasmid (h) - sc-407282 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ELOVL3 HDR Plasmid (h) - sc-407282-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ELOVL3 Double Nickase Plasmid (h) - sc-407282-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ELOVL3 Double Nickase Plasmid (h2) - sc-407282-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ELOVL3 CRISPR Activation Plasmid (h) - sc-407282-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ELOVL3 CRISPR Activation Plasmid (h2) - sc-407282-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ELOVL3 Lentiviral Activation Particles (h) - sc-407282-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ELOVL3 Lentiviral Activation Particles (h2) - sc-407282-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

ELOVL3 siRNA (h) - sc-62267 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ELOVL3 shRNA Plasmid (h) - sc-62267-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

ELOVL3 shRNA (h) Lentiviral Particles - sc-62267-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

MISSION® esiRNA - EHU030951 from Sigma-Aldrich Category siRNA Prices $250.00 Sizes 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN7822 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND7822 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR02182 from Sigma-Aldrich Category miRNA

ELOVL3 siRNA (Human) - CRJ3091 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ELOVL3 - MBS8204219 from MyBioSource Prices $365.00, $515.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

shRNA set against Human ELOVL3 (NM_152310.1) - SHH285269 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human ELOVL3(NM_152310.1) - SHH031727 from Creative biogene Category siRNA Species Reactivities Human

ELOVL3 CRISPR/Cas9 KO Plasmid (h2) - sc-407282-KO-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

ELOVL3 HDR Plasmid (h2) - sc-407282-HDR-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

Human ELOVL3 siRNA - orb273592 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

ELOVL3 shRNA Plasmid (Human) - CHJ3091 from Cohesion Biosciences Category siRNA Prices $500.00, $750.00 Sizes 150 µg, 300 µg Species Reactivities Human

ELOVL3 miRNA 3'UTR clone - MiUTR4H-TG03060 from Creative biogene Species Reactivities Human

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