| Gene Symbol |
NFYA
|
| Entrez Gene |
4800
|
| Alt Symbol |
CBF-A, CBF-B, HAP2, NF-YA
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
nuclear transcription factor Y, alpha
|
| Other Description |
CAAT box DNA-binding protein subunit A|CAAT-box DNA binding protein subunit A|CCAAT-binding transcription factor subunit B|HAP2 CCAAT-binding protein|Transcription factor NF-Y, A subunit|nuclear transcription factor Y subunit A|nuclear transcription factor Y subunit alpha
|
| Swissprots |
Q8IXU0 P23511
|
| Accessions |
EAX04013 EAX04014 EAX04015 EAX04016 EAX04017 EAX04018 EAX04019 EAX04020 EAX04021 P23511 AA905268 AJ420494 AK002098 AK025201 BC026923 BC039244 AAH39244 BM561405 BQ184804 EU446898 ABZ92427 GQ167198 ADD81252 M59079 AAA35950 X59711 CAA42231 NM_002505 NP_002496 NM_021705 NP_068351
|
| Function |
Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'- CCAAT-3' box motif found in the promoters of its target genes. NF- Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1. {ECO:0000269|PubMed:12741956}.
|
| Subcellular Location |
Nucleus.
|
| Top Pathways |
Tuberculosis, Antigen processing and presentation
|