Gene Symbol | NFYA |
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Entrez Gene | 4800 |
Alt Symbol | CBF-A, CBF-B, HAP2, NF-YA |
Species | Human |
Gene Type | protein-coding |
Description | nuclear transcription factor Y, alpha |
Other Description | CAAT box DNA-binding protein subunit A|CAAT-box DNA binding protein subunit A|CCAAT-binding transcription factor subunit B|HAP2 CCAAT-binding protein|Transcription factor NF-Y, A subunit|nuclear transcription factor Y subunit A|nuclear transcription factor Y subunit alpha |
Swissprots | Q8IXU0 P23511 |
Accessions | EAX04013 EAX04014 EAX04015 EAX04016 EAX04017 EAX04018 EAX04019 EAX04020 EAX04021 P23511 AA905268 AJ420494 AK002098 AK025201 BC026923 BC039244 AAH39244 BM561405 BQ184804 EU446898 ABZ92427 GQ167198 ADD81252 M59079 AAA35950 X59711 CAA42231 NM_002505 NP_002496 NM_021705 NP_068351 |
Function | Component of the sequence-specific heterotrimeric transcription factor (NF-Y) which specifically recognizes a 5'- CCAAT-3' box motif found in the promoters of its target genes. NF- Y can function as both an activator and a repressor, depending on its interacting cofactors. NF-YA positively regulates the transcription of the core clock component ARNTL/BMAL1. {ECO:0000269|PubMed:12741956}. |
Subcellular Location | Nucleus. |
Top Pathways | Tuberculosis, Antigen processing and presentation |
NF-YA CRISPR/Cas9 KO Plasmid (h) - sc-401085 from Santa Cruz Biotechnology
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NF-YA HDR Plasmid (h) - sc-401085-HDR from Santa Cruz Biotechnology
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NF-YA Double Nickase Plasmid (h) - sc-401085-NIC from Santa Cruz Biotechnology
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NF-YA Double Nickase Plasmid (h2) - sc-401085-NIC-2 from Santa Cruz Biotechnology
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NF-YA CRISPR Activation Plasmid (h) - sc-401085-ACT from Santa Cruz Biotechnology
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NF-YA CRISPR Activation Plasmid (h2) - sc-401085-ACT-2 from Santa Cruz Biotechnology
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NF-YA Lentiviral Activation Particles (h) - sc-401085-LAC from Santa Cruz Biotechnology
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NF-YA Lentiviral Activation Particles (h2) - sc-401085-LAC-2 from Santa Cruz Biotechnology
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NF-YA siRNA (h) - sc-29947 from Santa Cruz Biotechnology
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NF-YA shRNA Plasmid (h) - sc-29947-SH from Santa Cruz Biotechnology
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NF-YA shRNA (h) Lentiviral Particles - sc-29947-V from Santa Cruz Biotechnology
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NFYA RNAi - H00004800-R01 from Novus Biologicals
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NFYA RNAi - H00004800-R02 from Novus Biologicals
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MISSION® esiRNA - EHU134141 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1507 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1508 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN1509 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1507 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1508 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND1509 from Sigma-Aldrich
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MISSION® 3′UTR Lenti GoClone™ - HUTR09968 from Sigma-Aldrich
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NFYA siRNA (Human) - CRH3186 from Cohesion Biosciences
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shRNA set against Human NFYA (NM_002505.4) - SHH352032 from Creative biogene
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Human NFYA siRNA - orb263688 from Biorbyt
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NFYA shRNA Plasmid (Human) - CHH3186 from Cohesion Biosciences
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