RUSC1

Gene Symbol	RUSC1
Entrez Gene	23623
Alt Symbol	NESCA
Species	Human
Gene Type	protein-coding
Description	RUN and SH3 domain containing 1
Other Description	RUN and SH3 domain-containing protein 1|new molecule containing SH3 at the carboxy-terminus
Swissprots	Q9Y4T5 Q5T9V1 Q9UPY4 Q5T9V0 Q5T9U9 Q9BVN2 Q5T9V2 B3KWM9
Accessions	CAF86864 EAW53069 EAW53070 EAW53071 EAW53072 Q9BVN2 AB026894 BAA77507 AK055451 AK074485 AK074982 BAG52045 AK093777 AK125378 BAG54191 AK298730 BAG60880 AK307736 AK314559 BAG37144 AL080083 CAB45702 BC001045 AAH01045 BC004293 AAH04293 BC025680 BC028055 BC052277 AAH52277 BC131492 BQ004124 BX402179 BX640612 CAE45718 CN305634 CR749671 CAH18462 DA099897 DA131200 DA751328 DQ893622 ABM84548 DQ895385 ABM86311 XM_006711254 XP_006711317 XM_006711256 XP_006711319 XM_006711257 XP_006711320 XM_006711258 XP_006711321 XR_921763 NM_001105203 NP_001098673 NM_001105204 NP_001098674 NM_001105205 NP_001098675 NM_001278227 NP_001265156 NM_001278228 NP_001265157 NM_001278229 NP_001265158 NM_001278230 NP_001265159 NM_014328 NP_055143 NR_103478
Function	Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF- dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway. {ECO:0000269|PubMed:19365808}.
Subcellular Location	Cytoplasm. Nucleus. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Early endosome {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Golgi apparatus {ECO:0000250}. Note=Translocated to the nuclear envelope upon stimulation with NGF. Associated with membranes and microtubules (By similarity). {ECO:0000250}.
Tissue Specificity	Predominantly expressed in brain.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Anti-RUSC1 antibody - ab91561 from Abcam Prices $370.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RUSC1 antibody - ab68645 from Abcam Prices $370.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-RUSC1 Antibody (C-Terminus) - LS-C108597 from LifeSpan Bioscience Prices $325.00, $890.00 Sizes 100 µg, 500 µg Host Rabbit Clonality Polyclonal

RUSC1 Antibody - NBP1-81005 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RUSC1 Antibody - NBP1-81004 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RUSC1 Antibody - NBP1-81006 from Novus Biologicals Prices $419.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RUSC1 Antibody - H00023623-B01 from Novus Biologicals Prices $349.00 Sizes 50 µl Host Mouse Clonality Polyclonal

RUSC1 Antibody - H00023623-B01P from Novus Biologicals Prices $359.00 Sizes 50 µg Host Mouse Clonality Polyclonal

RUSC1 Polyclonal Antibody - bs-13677R from Bioss Prices $269.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RUSC1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-13677R-A350 from Bioss Prices $369.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RUSC1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-13677R-A488 from Bioss Prices $369.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RUSC1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-13677R-A555 from Bioss Prices $369.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RUSC1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-13677R-A647 from Bioss Prices $369.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RUSC1 Polyclonal Antibody, Cy3 Conjugated - bs-13677R-Cy3 from Bioss Prices $369.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RUSC1 Polyclonal Antibody, Cy5 Conjugated - bs-13677R-Cy5 from Bioss Prices $369.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RUSC1 Polyclonal Antibody, Cy5.5 Conjugated - bs-13677R-Cy5.5 from Bioss Prices $369.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RUSC1 Polyclonal Antibody, Cy7 Conjugated - bs-13677R-Cy7 from Bioss Prices $369.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RUSC1 Polyclonal Antibody, FITC Conjugated - bs-13677R-FITC from Bioss Prices $369.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RUSC1 Polyclonal Antibody, Biotin Conjugated - bs-13677R-Biotin from Bioss Prices $349.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RUSC1 Polyclonal Antibody, HRP Conjugated - bs-13677R-HRP from Bioss Prices $369.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-RUSC1 antibody produced in rabbit - HPA028510 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

Anti-RUSC1 antibody produced in mouse - SAB1400466 from Sigma-Aldrich Prices $347.00 Sizes 50 µg Host Mouse Clonality Polyclonal

Anti-RUSC1 antibody produced in rabbit - SAB3500106 from Sigma-Aldrich Prices $316.00 Sizes 100 µg Host Rabbit Clonality Polyclonal

Anti-RUSC1 antibody produced in rabbit - HPA029923 from Sigma-Aldrich Prices $429.00 Sizes 100 µl Host Rabbit Clonality Polyclonal

RUSC1 antibody - orb75281 from Biorbyt Prices $723.00 Sizes 100 μg Host Rabbit Clonality Polyclonal

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