RUSC1

Gene Symbol RUSC1
Entrez Gene 23623
Alt Symbol NESCA
Species Human
Gene Type protein-coding
Description RUN and SH3 domain containing 1
Other Description RUN and SH3 domain-containing protein 1|new molecule containing SH3 at the carboxy-terminus
Swissprots Q9Y4T5 Q5T9V1 Q9UPY4 Q5T9V0 Q5T9U9 Q9BVN2 Q5T9V2 B3KWM9
Accessions CAF86864 EAW53069 EAW53070 EAW53071 EAW53072 Q9BVN2 AB026894 BAA77507 AK055451 AK074485 AK074982 BAG52045 AK093777 AK125378 BAG54191 AK298730 BAG60880 AK307736 AK314559 BAG37144 AL080083 CAB45702 BC001045 AAH01045 BC004293 AAH04293 BC025680 BC028055 BC052277 AAH52277 BC131492 BQ004124 BX402179 BX640612 CAE45718 CN305634 CR749671 CAH18462 DA099897 DA131200 DA751328 DQ893622 ABM84548 DQ895385 ABM86311 XM_006711254 XP_006711317 XM_006711256 XP_006711319 XM_006711257 XP_006711320 XM_006711258 XP_006711321 XR_921763 NM_001105203 NP_001098673 NM_001105204 NP_001098674 NM_001105205 NP_001098675 NM_001278227 NP_001265156 NM_001278228 NP_001265157 NM_001278229 NP_001265158 NM_001278230 NP_001265159 NM_014328 NP_055143 NR_103478
Function Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF- dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway. {ECO:0000269|PubMed:19365808}.
Subcellular Location Cytoplasm. Nucleus. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Early endosome {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Golgi apparatus {ECO:0000250}. Note=Translocated to the nuclear envelope upon stimulation with NGF. Associated with membranes and microtubules (By similarity). {ECO:0000250}.
Tissue Specificity Predominantly expressed in brain.

RUSC1-Over-expression-Lysate - LY14144a from Abgent, a WuXi AppTec company

Category Cell Lysate
Prices $325.00
Sizes 100 µg
Western blot analysis of his-tag RUSC1 (arrow) using his tag antibody. 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the RUSC1 gene.

RUSC1 293T Cell Transient Overexpression Lysate(Denatured) - H00023623-T01 from Acris Antibodies

Category Cell Lysate
Prices $320.00
Sizes 100 µl

RUSC1 overexpression lysate - LY415356 from Acris Antibodies

Category Cell Lysate
Prices $280.00
Sizes 100 µg

RUSC1 293 Cell Lysate - 407233 from ABBIOTEC

Category Cell Lysate
Prices $392.00
Sizes 100 µg

RUSC1 Overexpression Lysate (Denatured) - H00023623-T01 from Novus Biologicals

Category Cell Lysate
Prices $279.00
Sizes 100 µl
RUSC1 transfected lysate.

RUSC1 Overexpression Lysate (Native) - NBL1-15630 from Novus Biologicals

Category Cell Lysate
Prices $329.00
Sizes 100 µg
Western Blot: RUSC1 Overexpression Lysate (Adult Normal) [NBL1-15630] Left-Empty vector transfected control cell lysate (HEK293 cell lysate); Right -Over-expression Lysate for RUSC1.

RUSC1 Over-expression Lysate Product - GWB-8F08EB from Genway Biotech

Category Cell Lysate
Prices $346.00
Sizes 100 µg
Species Human

Panoply™ Human RUSC1 Knockdown Stable Cell Line - CSC-DC013696 from Creative biogene

Category Cell Line
Species Human
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