RUSC1

Gene Symbol	RUSC1
Entrez Gene	23623
Alt Symbol	NESCA
Species	Human
Gene Type	protein-coding
Description	RUN and SH3 domain containing 1
Other Description	RUN and SH3 domain-containing protein 1|new molecule containing SH3 at the carboxy-terminus
Swissprots	Q9Y4T5 Q5T9V1 Q9UPY4 Q5T9V0 Q5T9U9 Q9BVN2 Q5T9V2 B3KWM9
Accessions	CAF86864 EAW53069 EAW53070 EAW53071 EAW53072 Q9BVN2 AB026894 BAA77507 AK055451 AK074485 AK074982 BAG52045 AK093777 AK125378 BAG54191 AK298730 BAG60880 AK307736 AK314559 BAG37144 AL080083 CAB45702 BC001045 AAH01045 BC004293 AAH04293 BC025680 BC028055 BC052277 AAH52277 BC131492 BQ004124 BX402179 BX640612 CAE45718 CN305634 CR749671 CAH18462 DA099897 DA131200 DA751328 DQ893622 ABM84548 DQ895385 ABM86311 XM_006711254 XP_006711317 XM_006711256 XP_006711319 XM_006711257 XP_006711320 XM_006711258 XP_006711321 XR_921763 NM_001105203 NP_001098673 NM_001105204 NP_001098674 NM_001105205 NP_001098675 NM_001278227 NP_001265156 NM_001278228 NP_001265157 NM_001278229 NP_001265158 NM_001278230 NP_001265159 NM_014328 NP_055143 NR_103478
Function	Putative signaling adapter which may play a role in neuronal differentiation. May be involved in regulation of NGF- dependent neurite outgrowth. Proposed to play a role in neuronal vesicular trafficking, specifically involving pre-synaptic membrane proteins. Seems to be involved in signaling pathways that are regulated by the prolonged activation of MAPK. Can regulate the polyubiquitination of IKBKG and thus may be involved in regulation of the NF-kappa-B pathway. {ECO:0000269|PubMed:19365808}.
Subcellular Location	Cytoplasm. Nucleus. Cytoplasm, cytoskeleton {ECO:0000250}. Cytoplasmic vesicle {ECO:0000250}. Early endosome {ECO:0000250}. Cell junction, synapse, postsynaptic cell membrane, postsynaptic density {ECO:0000250}. Golgi apparatus {ECO:0000250}. Note=Translocated to the nuclear envelope upon stimulation with NGF. Associated with membranes and microtubules (By similarity). {ECO:0000250}.
Tissue Specificity	Predominantly expressed in brain.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human RUSC1 full length protein - ab161721 from Abcam Category Protein Source Wheat germ Species Human

RUSC1 Antibody Blocking Peptide - LS-E30783 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 50 µg

Recombinant Human RUSC1 Protein - H00023623-P01 from Novus Biologicals Category Protein Prices $319.00 Sizes 2 µg Source Wheat Germ Species Human

RUSC1 Peptide - NBP1-76308PEP from Novus Biologicals Category Peptide Prices $149.00 Sizes 50 µg Species Human

RUSC1 Peptide - GTX85244-PEP from GeneTex Category Peptide Prices $149.00 Sizes 50 μg Species Human

NESCA - H00023623-P01 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Species Human

NESCA Control Peptide - AP30747CP-N from Acris Antibodies Category Peptide Prices $135.00 Sizes 50 µg

RUSC1 Peptide - 5411P from ProSci Category Peptide Species Human

RUSC2 Peptide - 6659P from ProSci Category Peptide Species Human

RUSC2 Peptide - 5413P from ProSci Category Peptide Species Human

RUSC1 fusion protein - Ag6073 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PET28a Species Human

RUSC1 fusion protein - Ag5815 from Proteintech Group Category Protein Prices $199.00 Sizes 50 μg Source E. coli -derived, PGEX-4T Species Human

Recombinant Human RUSC1, His-tagged - RUSC1-2473H from Creative Biomart Category Protein Source E.coli Species Human

Recombinant Human RUN and SH3 domain-containing protein 1(RUSC1) ,partial - CSB-YP871585HU CSB-EP871585HU CSB-BP871585HU CSB-MP871585HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

NESCA (transcript variant 4) - TP300243 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

RUSC1 Recombinant Protein Antigen - NBP1-81006PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RUSC1 Recombinant Protein Antigen - NBP1-81005PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RUSC1 Recombinant Protein Antigen - NBP1-81004PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

RUSC1 Peptide, Human - M34GP13696H from Creative Peptides Category Peptide Source Synthetic. Species Human

RUSC1 Antibody - SH-A15420 from Novatein Biosciences Prices $315.00 Sizes 100 µl Species Human, Mouse, Rat

RUN and SH3 domain-containing protein 1 (RUSC1), partial, Recombinant Protein - MBS1292031 from MyBioSource Category Protein Source E Coli or Yeast or Baculovirus or Mammalian Cell Species Human

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