Gene Symbol |
INTS12
|
Entrez Gene |
57117
|
Alt Symbol |
INT12, PHF22, SBBI22
|
Species |
Human
|
Gene Type |
protein-coding
|
Description |
integrator complex subunit 12
|
Other Description |
PHD finger protein 22|hypothetical nuclear factor SBBI22
|
Swissprots |
B2RC48 Q3B6Z3 Q96CB8 Q9HD71
|
Accessions |
CAK32203 EAX06189 EAX06190 Q96CB8 AF242524 AAF99604 AK314939 BAG37445 BC014442 AAH14442 BK005729 DAA05729 HQ447281 ADQ31768 XM_005263148 XP_005263205 XM_011532143 XP_011530445 XM_011532144 XP_011530446 XM_011532145 XP_011530447 XR_938768 NM_001142471 NP_001135943 NM_020395 NP_065128
|
Function |
Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes.
|
Subcellular Location |
Nucleus {ECO:0000305}.
|