Gene Symbol | INTS12 |
---|---|
Entrez Gene | 57117 |
Alt Symbol | INT12, PHF22, SBBI22 |
Species | Human |
Gene Type | protein-coding |
Description | integrator complex subunit 12 |
Other Description | PHD finger protein 22|hypothetical nuclear factor SBBI22 |
Swissprots | B2RC48 Q3B6Z3 Q96CB8 Q9HD71 |
Accessions | CAK32203 EAX06189 EAX06190 Q96CB8 AF242524 AAF99604 AK314939 BAG37445 BC014442 AAH14442 BK005729 DAA05729 HQ447281 ADQ31768 XM_005263148 XP_005263205 XM_011532143 XP_011530445 XM_011532144 XP_011530446 XM_011532145 XP_011530447 XR_938768 NM_001142471 NP_001135943 NM_020395 NP_065128 |
Function | Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. |
Subcellular Location | Nucleus {ECO:0000305}. |