Gene Symbol | INTS12 |
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Entrez Gene | 57117 |
Alt Symbol | INT12, PHF22, SBBI22 |
Species | Human |
Gene Type | protein-coding |
Description | integrator complex subunit 12 |
Other Description | PHD finger protein 22|hypothetical nuclear factor SBBI22 |
Swissprots | B2RC48 Q3B6Z3 Q96CB8 Q9HD71 |
Accessions | CAK32203 EAX06189 EAX06190 Q96CB8 AF242524 AAF99604 AK314939 BAG37445 BC014442 AAH14442 BK005729 DAA05729 HQ447281 ADQ31768 XM_005263148 XP_005263205 XM_011532143 XP_011530445 XM_011532144 XP_011530446 XM_011532145 XP_011530447 XR_938768 NM_001142471 NP_001135943 NM_020395 NP_065128 |
Function | Component of the Integrator complex, a complex involved in the small nuclear RNAs (snRNA) U1 and U2 transcription and in their 3'-box-dependent processing. The Integrator complex is associated with the C-terminal domain (CTD) of RNA polymerase II largest subunit (POLR2A) and is recruited to the U1 and U2 snRNAs genes. |
Subcellular Location | Nucleus {ECO:0000305}. |
INTS12 CRISPR/Cas9 KO Plasmid (h) - sc-412757 from Santa Cruz Biotechnology
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INTS12 HDR Plasmid (h) - sc-412757-HDR from Santa Cruz Biotechnology
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INTS12 Double Nickase Plasmid (h) - sc-412757-NIC from Santa Cruz Biotechnology
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INTS12 Double Nickase Plasmid (h2) - sc-412757-NIC-2 from Santa Cruz Biotechnology
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INTS12 CRISPR Activation Plasmid (h) - sc-412757-ACT from Santa Cruz Biotechnology
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INTS12 CRISPR Activation Plasmid (h2) - sc-412757-ACT-2 from Santa Cruz Biotechnology
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INTS12 Lentiviral Activation Particles (h) - sc-412757-LAC from Santa Cruz Biotechnology
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INTS12 Lentiviral Activation Particles (h2) - sc-412757-LAC-2 from Santa Cruz Biotechnology
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INTS12 siRNA (h) - sc-89129 from Santa Cruz Biotechnology
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INTS12 shRNA Plasmid (h) - sc-89129-SH from Santa Cruz Biotechnology
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INTS12 shRNA (h) Lentiviral Particles - sc-89129-V from Santa Cruz Biotechnology
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MISSION® esiRNA - EHU033331 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit - CKOZFN10711 from Sigma-Aldrich
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CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND10711 from Sigma-Aldrich
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INTS12 siRNA (Human) - CRJ1333 from Cohesion Biosciences
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PHF22 RNAi - H00057117-R01 from Novus Biologicals
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INTS12 - MBS8226118 from MyBioSource
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shRNA set against Human INTS12 (NM_020395.3) - SHH319953 from Creative biogene
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INTS12 shRNA Plasmid (Human) - CHJ1333 from Cohesion Biosciences
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INTS12 miRNA 3'UTR clone - MiUTR3H-11827 from Creative biogene
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INTS12 miRNA 3'UTR clone - MiUTR3H-11828 from Creative biogene
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