CYP2C9

Gene Symbol	CYP2C9
Entrez Gene	1559
Alt Symbol	CPC9, CYP2C, CYP2C10, CYPIIC9, P450IIC9
Species	Human
Gene Type	protein-coding
Description	cytochrome P450, family 2, subfamily C, polypeptide 9
Other Description	cytochrome P-450 S-mephenytoin 4-hydroxylase|cytochrome P-450MP|cytochrome P450 2C9|cytochrome P450 PB-1|flavoprotein-linked monooxygenase|microsomal monooxygenase|xenobiotic monooxygenase
Swissprots	Q5VX92 Q16756 Q8WW80 P11712 Q16872 Q6IRV8 P11713
Accessions	AAD13466 AAD13467 AAP88931 AAT94065 AAW83816 AGS09717 AGS09718 AGS09719 AGS09720 AGS09721 AGS09722 AGS09723 AGS09724 AGS09725 AGS09726 AGS09727 AGS09728 AGS09729 AGS09730 AGS09731 AGS09732 AGS09733 AGS09734 AGS09735 AGS09736 AGS09737 AGS09738 AGS09739 AGS09740 AGS09741 AGS09742 AGS09743 AGS09744 AGS09745 AGS09746 AGS09747 AGS09748 AGS09749 AGS09750 AGS09751 AGS09752 AGS09753 AGS09754 AGS09755 AGS09756 AGS09757 AGS09758 AGS09759 AGS09760 AGS09761 AGS09762 AGS09763 AGS09764 AIZ77478 AIZ77479 EAW50019 EAW50020 P11712 AK289420 BAF82109 AK298458 BAG60671 BC020754 AAH20754 BC070317 AAH70317 BC125054 AAI25055 BJ993098 D00173 BAA00123 M15331 AAA52157 M21939 AAA52158 M21940 AAA52159 M61855 M61857 S46963 AAB23864 NM_000771 NP_000762
Function	Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. This enzyme contributes to the wide pharmacokinetics variability of the metabolism of drugs such as S- warfarin, diclofenac, phenytoin, tolbutamide and losartan.
Subcellular Location	Endoplasmic reticulum membrane; Peripheral membrane protein. Microsome membrane; Peripheral membrane protein.
Top Pathways	Chemical carcinogenesis, Arachidonic acid metabolism, Linoleic acid metabolism, Retinol metabolism, Metabolism of xenobiotics by cytochrome P450

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

CYP2C9 / Cytochrome P450 2C9 Antibody Blocking Peptide - LS-E9335 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CYP2C9 / Cytochrome P450 2C9 Antibody Blocking Peptide - LS-E9343 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

CYP2C9 / Cytochrome P450 2C9 Antibody Blocking Peptide - LS-E15381 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Cytochrome P450 2C9 Recombinant Protein - H00001559-P01 from Novus Biologicals Category Protein Prices $369.00 Sizes 2 µg Species Human

CYP2C9-Antibody-Center-Blocking-Peptide - BP7881c from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CYP2C9-Antibody-N-term-Blocking-Peptide - BP7874a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

CYP2C9 Blocking Peptide - 33R-1211 from Fitzgerald Category Peptide Prices $130.00 Sizes 100 µg

Cytochrome P450 2C9 Blocking Peptide - abx062508 from Abbexa Category Peptide Species Human, Mouse, Rat

CYP2C9 - H00001559-P01-10 from Acris Antibodies Category Protein Prices $370.00 Sizes 10 µg Source in vitro transl. Species Human

CYP2C9 - H00001559-P01-25 from Acris Antibodies Category Protein Prices $520.00 Sizes 25 µg Source in vitro transl. Species Human

CYP2C9 fusion protein - ag9881 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

CYP2C9 fusion protein - ag9566 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

Recombinant Human CYP2C9, GST-tagged - CYP2C9-530H from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Human CYP2C9 1(Wild type allele) - CYP2C9-543H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human CYP2C9 2 (R144C) - CYP2C9-544H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human CYP2C9 3 (I359L) - CYP2C9-545H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human CYP2C9 - CYP2C9-537H from Creative Biomart Category Protein Source Insect cells.

Cytochrome P450 2C9 Blocking Peptide - CBP1314 from Cohesion Biosciences Category Peptide Prices $100.00, $300.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

CYP2C9 Peptide - BS60309P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Cytochrome P450 2C9(CYP2C9) - CSB-YP006419HU CSB-EP006419HU CSB-BP006419HU CSB-MP006419HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

EZCyp™ Active Human Cytochrome P450 2C9 - 7875-10 from Biovision Category Protein Prices $125.00 Sizes 10 mg Source Pichia pastoris Species Human

EZCyp™ Active Human Cytochrome P450 2C9 - 7875-50 from Biovision Category Protein Prices $475.00 Sizes 50 mg Source Pichia pastoris Species Human

CYP2C9 - TP320997 from Acris Antibodies Category Protein Prices $680.00 Sizes 20 µg Source HEK293 cells Species Human

Recombinant Human CYP2C9/NADPH reductase protein - CYP2C9-35H from Creative Biomart Category Protein Source Pichia pastoris Species Human

Recombinant Human CYP2C9 protein, MYC/DDK-tagged - CYP2C9-531H from Creative Biomart Category Protein Source HEK293 Species Human

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