PAPSS2

Gene Symbol	PAPSS2
Entrez Gene	9060
Alt Symbol	ATPSK2, BCYM4, SK2
Species	Human
Gene Type	protein-coding
Description	3'-phosphoadenosine 5'-phosphosulfate synthase 2
Other Description	3-prime-phosphoadenosine 5-prime-phosphosulfate synthase 2|ATP sulfurylase/APS kinase 2|ATP sulfurylase/adenosine 5'-phosphosulfate kinase|PAPS synthase 2|PAPS synthetase 2|SK 2|bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 2|bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthethase 2
Swissprots	Q9UP30 Q9UHM1 Q9P0G6 O95340 Q9BZL2 Q9UKD3
Accessions	AAF40307 EAW50181 EAW50182 EAW50183 O95340 AF074331 AAD38423 AF091242 AAC64583 AF150754 AAF20366 AF173365 AAF12761 AF313907 AAK00296 AK301453 BAG62977 AK309262 AK312556 BAG35453 BC009894 AAH09894 BQ221395 BQ772647 BQ888954 CB960618 DQ893625 ABM84551 DQ895430 ABM86356 NM_001015880 NP_001015880 NM_004670 NP_004661
Function	Bifunctional enzyme with both ATP sulfurylase and APS kinase activity, which mediates two steps in the sulfate activation pathway. The first step is the transfer of a sulfate group to ATP to yield adenosine 5'-phosphosulfate (APS), and the second step is the transfer of a phosphate group from ATP to APS yielding 3'-phosphoadenylylsulfate (PAPS: activated sulfate donor used by sulfotransferase). In mammals, PAPS is the sole source of sulfate; APS appears to be only an intermediate in the sulfate- activation pathway. May have a important role in skeletogenesis during postnatal growth (By similarity). {ECO:0000250}.
Tissue Specificity	Expressed in cartilage and adrenal gland. {ECO:0000269|PubMed:19474428}.
Top Pathways	Sulfur metabolism, Purine metabolism, Selenocompound metabolism

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

PAPSS 2 CRISPR/Cas9 KO Plasmid (h) - sc-409566 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PAPSS 2 HDR Plasmid (h) - sc-409566-HDR from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PAPSS 2 Double Nickase Plasmid (h) - sc-409566-NIC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PAPSS 2 Double Nickase Plasmid (h2) - sc-409566-NIC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PAPSS 2 CRISPR Activation Plasmid (h) - sc-409566-ACT from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PAPSS 2 CRISPR Activation Plasmid (h2) - sc-409566-ACT-2 from Santa Cruz Biotechnology Category CRISPR Prices $345.00 Sizes 20 µg Species Reactivities Human

PAPSS 2 Lentiviral Activation Particles (h) - sc-409566-LAC from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PAPSS 2 Lentiviral Activation Particles (h2) - sc-409566-LAC-2 from Santa Cruz Biotechnology Prices $345.00 Sizes 20 µg Species Reactivities Human

PAPSS 2 siRNA (h) - sc-61293 from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PAPSS 2 shRNA Plasmid (h) - sc-61293-SH from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PAPSS 2 shRNA (h) Lentiviral Particles - sc-61293-V from Santa Cruz Biotechnology Category siRNA Prices $258.00 Sizes 10 µm Species Reactivities Human

PAPSS2 RNAi - H00009060-R01V from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

PAPSS2 RNAi - H00009060-R03 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

MISSION® esiRNA - EHU079661 from Sigma-Aldrich Category siRNA Prices $140.00, $250.00 Sizes 20 µg, 50 µg

MISSION® siRNA - SIHK1520 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1521 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

MISSION® siRNA - SIHK1522 from Sigma-Aldrich Category siRNA Prices $25.00 Sizes 0.25 nmol

CompoZr® Knockout ZFN Kit - CKOZFN16321 from Sigma-Aldrich Category ZFN Kit Prices $4,999.00 Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND16321 from Sigma-Aldrich Category ZFN Kit Prices $3,999.00 Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10151 from Sigma-Aldrich Category miRNA Prices $350.00 Sizes hutr10151

PAPSS2 siRNA (Human) - CRH5980 from Cohesion Biosciences Category siRNA Prices $340.00, $510.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

PAPSS2 RNAi - H00009060-R04 from Novus Biologicals Category siRNA Prices $399.00 Sizes 20 nmol Species Reactivities Human

shRNA set against Human PAPSS2(NM_004670.3) - SHR087630 from Creative biogene Category siRNA Species Reactivities Human

shRNA set against Human PAPSS2(NM_001015880.1) - SHR087648 from Creative biogene Category siRNA Species Reactivities Human

Human PAPSS2 siRNA - orb266482 from Biorbyt Category siRNA Prices $485.00, $629.00 Sizes 15 nmol, 30 nmol Species Reactivities Human

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