Gene Symbol | SLC16A3 |
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Entrez Gene | 9123 |
Alt Symbol | MCT 3, MCT 4, MCT-3, MCT-4, MCT3, MCT4 |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 16 (monocarboxylate transporter), member 3 |
Other Description | monocarboxylate transporter 3|monocarboxylate transporter 4|solute carrier family 16 (monocarboxylic acid transporters), member 3|solute carrier family 16, member 3 (monocarboxylic acid transporter 4) |
Swissprots | B3KXG8 Q2M1P8 O15427 |
Accessions | EAW89753 EAW89754 EAW89755 EAW89756 EAW89757 O15427 AA448579 AK127319 BAG54480 AK223040 BAD96760 BC112267 AAI12268 BC112269 AAI12270 BM926587 BM980920 CX872345 DA373476 DA419716 DA583988 DA895850 HQ258434 ADR83188 U81800 AAC52015 XM_011523607 XP_011521909 NM_001042422 NP_001035887 NM_001042423 NP_001035888 NM_001206950 NP_001193879 NM_001206951 NP_001193880 NM_001206952 NP_001193881 NM_004207 NP_004198 |
Function | Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Multi-pass membrane protein. |
Tissue Specificity | Highly expressed in skeletal muscle. |
Top Pathways | Central carbon metabolism in cancer |
MCT4 (D-1) - sc-376140 from Santa Cruz Biotechnology
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MCT4 (F-10) - sc-376101 from Santa Cruz Biotechnology
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MCT4 (C-17) - sc-14930 from Santa Cruz Biotechnology
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MCT4 (G-7) - sc-376465 from Santa Cruz Biotechnology
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MCT4 (G-9) - sc-376139 from Santa Cruz Biotechnology
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MCT4 (H-90) - sc-50329 from Santa Cruz Biotechnology
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Anti-SLC16A3 antibody - ab74109 from Abcam
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Anti-SLC16A3 antibody - C-terminal - ab190497 from Abcam
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Anti-SLC16A3 antibody - C-terminal - ab170619 from Abcam
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Anti-SLC16A3 Antibody (C-Terminus) - LS-C25643 from LifeSpan Bioscience
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Anti-SLC16A3 Antibody (4th Cytoplasmic Domain) - LS-C25645 from LifeSpan Bioscience
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Anti-SLC16A3 Antibody (4th Cytoplasmic Domain) - LS-C25644 from LifeSpan Bioscience
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Anti-SLC16A3 Antibody (aa440-465, AP) - LS-C217543 from LifeSpan Bioscience
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Anti-SLC16A3 Antibody (aa440-465, Biotin) - LS-C217544 from LifeSpan Bioscience
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Anti-SLC16A3 Antibody (aa440-465, APC) - LS-C217545 from LifeSpan Bioscience
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Anti-SLC16A3 Antibody (aa440-465, Azide-free, HRP) - LS-C217547 from LifeSpan Bioscience
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Anti-SLC16A3 Antibody (aa440-465, FITC) - LS-C217546 from LifeSpan Bioscience
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Anti-SLC16A3 Antibody (aa440-465, PE) - LS-C217548 from LifeSpan Bioscience
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Anti-SLC16A3 Antibody (aa440-465) - LS-C330143 from LifeSpan Bioscience
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Anti-SLC16A3 Antibody (aa40-89) - LS-C135144 from LifeSpan Bioscience
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Anti-SLC16A3 Antibody (aa233-282) - LS-C120098 from LifeSpan Bioscience
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Anti-SLC16A3 Antibody (Phe265) - LS-C177471 from LifeSpan Bioscience
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Anti-SLC16A3 Antibody - LS-C331531 from LifeSpan Bioscience
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Anti-SLC16A3 Antibody (aa400-450) - LS-C291075 from LifeSpan Bioscience
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SLC16A3 Antibody - NBP1-81251 from Novus Biologicals
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