| Gene Symbol |
SLC16A3
|
| Entrez Gene |
9123
|
| Alt Symbol |
MCT 3, MCT 4, MCT-3, MCT-4, MCT3, MCT4
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
solute carrier family 16 (monocarboxylate transporter), member 3
|
| Other Description |
monocarboxylate transporter 3|monocarboxylate transporter 4|solute carrier family 16 (monocarboxylic acid transporters), member 3|solute carrier family 16, member 3 (monocarboxylic acid transporter 4)
|
| Swissprots |
B3KXG8 Q2M1P8 O15427
|
| Accessions |
EAW89753 EAW89754 EAW89755 EAW89756 EAW89757 O15427 AA448579 AK127319 BAG54480 AK223040 BAD96760 BC112267 AAI12268 BC112269 AAI12270 BM926587 BM980920 CX872345 DA373476 DA419716 DA583988 DA895850 HQ258434 ADR83188 U81800 AAC52015 XM_011523607 XP_011521909 NM_001042422 NP_001035887 NM_001042423 NP_001035888 NM_001206950 NP_001193879 NM_001206951 NP_001193880 NM_001206952 NP_001193881 NM_004207 NP_004198
|
| Function |
Proton-linked monocarboxylate transporter. Catalyzes the rapid transport across the plasma membrane of many monocarboxylates such as lactate, pyruvate, branched-chain oxo acids derived from leucine, valine and isoleucine, and the ketone bodies acetoacetate, beta-hydroxybutyrate and acetate (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cell membrane; Multi-pass membrane protein.
|
| Tissue Specificity |
Highly expressed in skeletal muscle.
|
| Top Pathways |
Central carbon metabolism in cancer
|