TNC

Gene Symbol	TNC
Entrez Gene	3371
Alt Symbol	150-225, DFNA56, GMEM, GP, HXB, JI, TN, TN-C
Species	Human
Gene Type	protein-coding
Description	tenascin C
Other Description	GP 150-225|cytotactin|deafness, autosomal dominant 56|glioma-associated-extracellular matrix antigen|hexabrachion (tenascin)|myotendinous antigen|neuronectin|tenascin|tenascin-C additional domain 1|tenascin-C isoform 14/AD1/16
Swissprots	Q14583 C9J6D9 Q5T7S3 Q15567 P24821 C9J575 C9IYT7 C9J848
Accessions	EAW87434 EAW87435 P24821 AB210038 BAE06120 AI266750 AI964017 AK304015 BAG64930 BC151843 AAI51844 BP278052 BP279008 BQ575939 BQ880861 BU860660 BX100095 BX641111 CAE46051 CX871573 EU295718 ABX89318 GU473235 ADD10730 M24630 AAA52703 M55618 AAA88083 M96686 AAA36728 X56160 CAA39628 X78565 CAA55309 X80280 XM_005251972 XP_005252029 XM_005251973 XP_005252030 XM_005251974 XP_005252031 XM_005251975 XP_005252032 XM_006717096 XP_006717159 XM_006717097 XP_006717160 XM_006717098 XP_006717161 XM_006717100 XP_006717163 XM_006717101 XP_006717164 XM_011518622 XP_011516924 XM_011518623 XP_011516925 XM_011518624 XP_011516926 XM_011518625 XP_011516927 XM_011518626 XP_011516928 XM_011518627 XP_011516929 XM_011518628 XP_011516930 XM_011518629 XP_011516931 XM_011518630 XP_011516932 NM_002160 NP_002151
Function	Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
Subcellular Location	Secreted, extracellular space, extracellular matrix.
Top Pathways	Focal adhesion, ECM-receptor interaction, PI3K-Akt signaling pathway, MicroRNAs in cancer

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human Tenascin C protein fragment - ab114943 from Abcam Category Protein Source Wheat germ Species Human

Tenascin C blocking peptide - GTX88219-PEP from GeneTex Category Peptide Prices $239.00 Sizes 100 μg Species Human

Recombinant Human Tenascin C, CF - 3358-TC-050 from R&D Systems Category Protein Source Mouse myeloma cell line, NS0-derived, Gly23-Pro625, with a C-terminal 6-His tag

Recombinant human Tenascin (OPCA00922) - OPCA00922 from Aviva Systems Biology Category Protein Prices $198.00 Sizes 50 µg Species Human

NATIVE Human TENASCIN Protein (OPSA10606) - OPSA10606 from Aviva Systems Biology Category Protein Prices $925.00 Sizes 100 µg Species Human

TNC peptide - orb217430 from Biorbyt Category Peptide Prices $272.00, $510.00 Sizes 1 mg, 5 mg Species Human, Mouse, Rat

Tenascin protein - 30R-3186 from Fitzgerald Category Protein Prices $210.00 Sizes 50 µg Source E.coli

Tenascin protein - 30R-3237 from Fitzgerald Category Protein Prices $210.00 Sizes 50 µg Source E.coli

Human Tenascin C Protein - abx069256 from Abbexa Category Protein Source E.coli Species Human

Tenascin C Blocking Peptide - abx062761 from Abbexa Category Peptide Species Human, Mouse, Rat, Pig

Tenascin C Peptide - AC21-1890-P from Abcore Category Peptide Prices $160.00 Sizes 100 µg

Tenascin / TNC / HXB - AR05088PU-N from Acris Antibodies Category Protein Prices $880.00 Sizes 100 µg Source Human Species Human

Tenascin / TNC / HXB - H00003371-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

Tenascin / TNC / HXB - H00003371-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

Native Human TENASCIN - DS-01-0412 from RayBiotech Category Protein Species Human

Tenascin C (TNC), Human - 20-8213 from ARP American Research Products Category Protein Prices $489.00 Sizes 50 µg Source E.coli Species Human

Tenascin C (TNC), Human - 20-8214 from ARP American Research Products Category Protein Prices $489.00 Sizes 50 µg Source E.coli Species Human

TNC Peptide - 42-295P from ProSci Category Peptide Prices $175.00 Sizes 100 µg

Recombinant Human TNC - TNC-143H from Creative Biomart Category Protein Source E.Coli Species Human

Recombinant Human TNC - TNC-31215TH from Creative Biomart Category Protein Source Wheat germ

Recombinant Human TNC, His-tagged - TNC-2170H from Creative Biomart Category Protein Source Mouse NS0 Cells Species Human

Recombinant Human TNC, His-tagged - TNC-734H from Creative Biomart Category Protein Source NSO cells Species Human

Native Human Tenascin C - TNC-50H from Creative Biomart Category Protein Species Human

Recombinant Tenascin C (TNC) - RPB975Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Tenascin C (TNC) - RPB975Mu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Mouse

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