TNC

Gene Symbol TNC
Entrez Gene 3371
Alt Symbol 150-225, DFNA56, GMEM, GP, HXB, JI, TN, TN-C
Species Human
Gene Type protein-coding
Description tenascin C
Other Description GP 150-225|cytotactin|deafness, autosomal dominant 56|glioma-associated-extracellular matrix antigen|hexabrachion (tenascin)|myotendinous antigen|neuronectin|tenascin|tenascin-C additional domain 1|tenascin-C isoform 14/AD1/16
Swissprots Q14583 C9J6D9 Q5T7S3 Q15567 P24821 C9J575 C9IYT7 C9J848
Accessions EAW87434 EAW87435 P24821 AB210038 BAE06120 AI266750 AI964017 AK304015 BAG64930 BC151843 AAI51844 BP278052 BP279008 BQ575939 BQ880861 BU860660 BX100095 BX641111 CAE46051 CX871573 EU295718 ABX89318 GU473235 ADD10730 M24630 AAA52703 M55618 AAA88083 M96686 AAA36728 X56160 CAA39628 X78565 CAA55309 X80280 XM_005251972 XP_005252029 XM_005251973 XP_005252030 XM_005251974 XP_005252031 XM_005251975 XP_005252032 XM_006717096 XP_006717159 XM_006717097 XP_006717160 XM_006717098 XP_006717161 XM_006717100 XP_006717163 XM_006717101 XP_006717164 XM_011518622 XP_011516924 XM_011518623 XP_011516925 XM_011518624 XP_011516926 XM_011518625 XP_011516927 XM_011518626 XP_011516928 XM_011518627 XP_011516929 XM_011518628 XP_011516930 XM_011518629 XP_011516931 XM_011518630 XP_011516932 NM_002160 NP_002151
Function Extracellular matrix protein implicated in guidance of migrating neurons as well as axons during development, synaptic plasticity as well as neuronal regeneration. Promotes neurite outgrowth from cortical neurons grown on a monolayer of astrocytes. Ligand for integrins alpha-8/beta-1, alpha-9/beta-1, alpha-V/beta-3 and alpha-V/beta-6.
Subcellular Location Secreted, extracellular space, extracellular matrix.
Top Pathways Focal adhesion, ECM-receptor interaction, PI3K-Akt signaling pathway, MicroRNAs in cancer

Tenascin C (D16C4) Rabbit mAb - 12221 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D16C4
Western blot analysis of extracts from mouse brain and rat brain using Tenascin C (D16C4) Rabbit mAb.

Tenascin-C (E-9) - sc-25328 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Tenascin-C (E-9): sc-25328. Immunoperoxidase staining of formalin fixed, paraffin-embedded human placenta tissue showing cytoplasmic staining of trophoblastic and decidual cells. Kindly provided by The Swedish Human Protein Atlas (HPA) program.

Tenascin-C (H-300) - sc-20932 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
Tenascin-C (H-300): sc-20932. Western blot analysis of Tenascin-C expression in Hs68 whole cell lysate.

Tenascin-C (N-19) - sc-9871 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
Tenascin-C (N-19): sc-9871. Immunoperoxidase staining of formalin fixed, paraffin-embedded human testis tissue showing membrane and cytoplasmic staining of cells in seminiferous ducts and Leydig cells.

Tenascin-C (F-17) - sc-9872 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Tenascin-C (300-3) - sc-13578 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
Tenascin-C (300-3): sc-13578. Immunofluorescence staining of methanol-fixed U-87 MG cells showing cytoplasmic localization.

Tenascin-C (BC-24) - sc-59884 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µl ascites
Host Mouse
Clonality Monoclonal

Anti-Tenascin antibody [B653M] - ab82449 from Abcam

Prices $359.00
Sizes 200 µg
Host Mouse
Clonality Monoclonal
Clone B653M
ab82449 staining Tenascin in Human mini-tumor spheroids by Immunohistochemistry (PFA perfusion fixed frozen sections). Spheroids were incubated with collagen type I solution for 40 hours (left) or 7 days (right). Spheroids were fixed with paraformaldehyde and incubated with primary antibody (in 1% BSA in PBS) overnight at room temperature. A fluorescent-conjugated donkey anti-mouse was used as the secondary antibody.

Anti-Tenascin C antibody - ab194331 from Abcam

Prices $376.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Anti-Tenascin C antibody (ab194331) at 1/500 dilution + SJCRH30 cell lysate at 50 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP Conjugate secondary antibody at 1/2500 dilution

Anti-Tenascin C antibody - ab58954 from Abcam

Prices $376.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Human sqamous cell carcinoma stained with ab58954 at a dilution of 1/50

Anti-Tenascin C antibody - ab99563 from Abcam

Prices $368.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-Tenascin C antibody - ab16290 from Abcam

Prices $376.00
Sizes 50 µg
Host Chicken
Clonality Polyclonal

Anti-Tenascin C antibody [BC-24] - ab6393 from Abcam

Prices $379.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone BC-24

Anti-Tenascin C antibody [DB7] - ab86182 from Abcam

Prices $379.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone DB7
Immunohistochemical analysis of Human cornea tissue, staining Tenascin C wih ab86182. Tissue was taken from healthy patients (left) or patients with granular dystrophy (right). Sections were blocked with blocking solution for 30 minutes at room temperature before incubation with primary antibody (1/50) overnight at 4°C. Staining was detected with DAB.

Anti-Tenascin C antibody [EB2] - ab88280 from Abcam

Prices $387.00
Sizes 50 µg
Host Mouse
Clonality Monoclonal
Clone EB2
ab88280, staining Tenascin C in vulva carcinoma frozen tissue sections by Immunohistochemistry.

Anti-Tenascin C antibody [EPR4219] - ab108930 from Abcam

Prices $395.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4219
Overlay histogram showing SH-SY5Y cells stained with ab108930 (red line). The cells were fixed with 4% paraformaldehyde (10 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab108930, 1/1000 dilution) for 30 min at 22°C. The secondary antibody used was DyLight® 488 goat anti-rabbit IgG (H+L) (ab96899) at 1/500 dilution for 30 min at 22°C. Isotype control antibody (black line) was rabbit IgG (monoclonal) (0.1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in SH-SY5Y cells fixed with 80% methanol (5 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-Tenascin C antibody [EPR4219] (HRP) - ab196918 from Abcam

Prices $425.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR4219
Anti-Tenascin C antibody [EPR4219] (HRP) (ab196918) at 1/5000 dilution + Brain (Human) Tissue Lysate - fetal normal tissue at 10 µgdeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Tenascin C antibody [SPM319], prediluted - ab54348 from Abcam

Prices $376.00
Sizes 7 ml
Host Mouse
Clonality Monoclonal
Clone SPM319
Ab54348 ready to use staining human squamous cell carcinoma; formalin fixed, paraffin embedded.

Anti-Tenascin C antibody [T2H5] - ab3970 from Abcam

Prices $384.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone T2H5
ab3970 staining paraffin embedded tissue sections.

Anti-Tenascin C antibody [T2H5] - ab58510 from Abcam

Prices $372.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal
Clone T2H5

Anti-TNC / Tenascin C Antibody (clone STn 219) - LS-C194633 from LifeSpan Bioscience

Prices $295.00
Sizes 500 µl
Host Mouse
Clonality Monoclonal

Anti-TNC / Tenascin C Antibody (clone 3B4) - LS-C197477 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3B4

Anti-TNC / Tenascin C Antibody (clone 4F10TT) - LS-C193612 from LifeSpan Bioscience

Prices $905.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 4F10TT

Anti-TNC / Tenascin C Antibody (clone T2H5) - LS-C202465 from LifeSpan Bioscience

Prices $305.00
Sizes 1 ml
Host Mouse
Clonality Monoclonal
Clone T2H5

Anti-TNC / Tenascin C Antibody (clone T20) - LS-C171285 from LifeSpan Bioscience

Prices $295.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone T20
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