CACNA2D4

Gene Symbol CACNA2D4
Entrez Gene 93589
Alt Symbol RCD4
Species Human
Gene Type protein-coding
Description calcium channel, voltage-dependent, alpha 2/delta subunit 4
Other Description voltage-dependent calcium channel subunit alpha-2/delta-4|voltage-gated calcium channel alpha(2)delta-4 subunit|voltage-gated calcium channel subunit alpha-2/delta-4
Swissprots Q8IZS9 Q86XZ5 Q7Z3S7 Q7Z3S8
Accessions EAW88918 EAW88919 EAW88920 Q7Z3S7 AA001411 AF516695 AAN06672 AI160471 AK301234 BAG62806 AL137658 BC048288 AAH48288 BC150186 AAI50187 BI908421 BX457018 BX537436 CAD97678 BX537437 CAD97679 CA443847 EU832150 ACE87500 EU832243 ACE86813 XM_011521041 XP_011519343 XR_931529 XR_931530 XR_931531 NM_172364 NP_758952 NM_001005737 NM_001005766
Function The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. {ECO:0000269|PubMed:12181424}.
Subcellular Location Membrane {ECO:0000305}; Single-pass type I membrane protein {ECO:0000305}.
Tissue Specificity Predominantly expressed in certain types of endocrine cells. Present in the Paneth cells of the small intestine. Also present in the erythroblasts in the fetal liver, in the cells of the zona reticularis of the adrenal gland and in the basophils of the pituitary. Present at low level in some brain regions such as the cerebellum (at protein level). {ECO:0000269|PubMed:12181424}.
Top Pathways MAPK signaling pathway, Cardiac muscle contraction, Hypertrophic cardiomyopathy (HCM), Arrhythmogenic right ventricular cardiomyopathy (ARVC), Dilated cardiomyopathy

Anti-Cacna2d4 antibody - N-terminal - ab175250 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Cacna2d4 antibody - N-terminal (ab175250) at 1/100 dilution + K562 cell lysate at 15 µg

Anti-CACNA2D4 antibody - ab81106 from Abcam

Host Rabbit
Clonality Polyclonal

Anti-Cacna2d4 antibody - ab135987 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-Cacna2d4 antibody (ab135987) at 1/500 dilution + COLO205 cell lysate at 30 µg

Anti-Cacna2d4 antibody - ab128281 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Cacna2d4 antibody (ab128281) at 1 µg/ml + Mouse pancreas lysate at 10 µgdeveloped using the ECL technique

Anti-CACNA2D4 Antibody (N-Terminus, AP) - LS-C208207 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CACNA2D4 Antibody (N-Terminus, APC) - LS-C208208 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CACNA2D4 Antibody (N-Terminus, Biotin) - LS-C208209 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CACNA2D4 Antibody (N-Terminus, FITC) - LS-C208210 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CACNA2D4 Antibody (aa535-584) - LS-C200193 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western blot of the lysates from COLO205 cells using CACNA2D4 antibody.

Anti-CACNA2D4 Antibody (aa341-390) - LS-C151368 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CACNA2D4 antibody Western Blot of Mouse Pancreas.

Anti-CACNA2D4 Antibody (N-Terminus, Azide-free, HRP) - LS-C208211 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CACNA2D4 Antibody (N-Terminus, PE) - LS-C208212 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CACNA2D4 Antibody (N-Terminus) - LS-C319970 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-CACNA2D4 Antibody (aa548-597) - LS-C291426 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-CACNA2D4 Antibody (aa757-806) - LS-C135628 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
CACNA2D4 antibody LS-C135628 Western blot of 293T cell lysate.

Anti-CACNA2D4 Antibody (aa151-200) - LS-C187345 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot of Human A549. CACNA2D4 antibody dilution 1.0 ug/ml.

Anti-CACNA2D4 Antibody (aa89-118) - LS-C168260 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
CACNA2D4 Antibody western blot of K562 cell line lysates (15 ug/lane). The CACNA2D4 antibody detected the CACNA2D4 protein (arrow).

CACNA2D4 Antibody - NBP1-68992 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: CACNA2D4 Antibody [NBP1-68992] - Titration: 0.2-1 ug/ml, Positive Control: 293T cell lysate.

CACNA2D4 Antibody - NBP1-85920 from Novus Biologicals

Prices $129.00, $419.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: CACNA2D4 Antibody [NBP1-85920] - Staining of human appendix shows strong positivity in a subset of glandular cells.

Anti-CACNA2D4 antibody produced in rabbit - SAB2107459 from Sigma-Aldrich

Prices $341.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-CACNA2D4: <B>Cat. No. SAB2107459</B>: Western blot analysis of CACNA2D4 with CACNA2D4 (calcium channel, voltage-dependent, alpha 2/delta subunit 4) antibody against the C terminal of CACNA2D4 (50 μg) antibody at 1.0 μg/mL.

Anti-CACNA2D4 antibody produced in rabbit - HPA031952 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-CACNA2D4: <B>Cat. No. HPA031952</B>: Immunohistochemical staining of human heart muscle shows strong cytoplasmic positivity in myocytes.

ANTI-CACNA2D4 (N-TERM) antibody produced in rabbit - SAB1303747 from Sigma-Aldrich

Prices $326.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

CACNA2D4 antibody - C-terminal region (ARP59811_P050) - ARP59811_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CACNA2D4 Antibody - middle region (ARP65632_P050) - ARP65632_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

CACNA2D4 Antibody - N-terminal region (OAAB03116) - OAAB03116 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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