MORC2

Gene Symbol MORC2
Entrez Gene 22880
Alt Symbol ZCW3, ZCWCC1
Species Human
Gene Type protein-coding
Description MORC family CW-type zinc finger 2
Other Description MORC family CW-type zinc finger protein 2|zinc finger CW-type coiled-coil domain protein 1|zinc finger, CW type with coiled-coil domain 1|zinc finger, CW-type with coiled-coil domain 1
Swissprots Q9UF28 B2RNB1 Q9Y6V2 Q9Y6X9
Accessions AAC12954 EAW59921 EAW59922 Q9Y6X9 AB020659 BAA74875 AL133637 CAB63760 BC019257 AAH19257 BC136782 AAI36783 BC141657 AAI41658 BQ448593 CR456469 CAG30355 CU013019 CAK54450 CU013307 CAK54749 DB047465 DR000665 XM_011530003 XP_011528305 XM_011530004 XP_011528306 XM_011530005 XP_011528307 XM_011530006 XP_011528308 NM_001303256 NP_001290185 NM_001303257 NP_001290186 NM_014941 NP_055756
Function Exhibits a cytosolic function in lipogenesis, adipogenic differentiation, and lipid homeostasis by increasing the activity of ACLY, possibly preventing its dephosphorylation. May act as a transcriptional repressor. Down-regulates CA9 expression. {ECO:0000269|PubMed:20110259, ECO:0000269|PubMed:20225202}.
Subcellular Location Nucleus {ECO:0000269|PubMed:20225202}. Cytoplasm, cytosol {ECO:0000269|PubMed:20225202, ECO:0000269|PubMed:24286864}. Note=Mainly located in the nucleus.
Tissue Specificity Highly expressed in smooth muscle, pancreas and testis.

ZCWCC1 (D-20) - sc-65002 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ZCWCC1 (D-20): sc-65002. Western blot analysis of ZCWCC1 expression in IMR-32 nuclear extract.

ZCWCC1 (F-17) - sc-65003 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
ZCWCC1 (F-17): sc-65003. Western blot analysis of ZCWCC1 expression in Jurkat (A) and IMR-32 (B) nuclear extracts.

ZCWCC1 (H-128) - sc-366271 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
ZCWCC1 (H-128): sc-366271. Western blot analysis of ZCWCC1 expression in Jurkat (A) and IMR-32 (B) whole cell lysates.

ZCWCC1 (Q-20) - sc-65005 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-ZCWCC1 (phospho S739) antibody - ab203347 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemical analysis of formalin-fixed, paraffin-embedded rat placenta sections labeling ZCWCC1 (phospho S739) with ab203347 at a 1/200 dilution, followed by conjugation to the secondary antibody and DAB staining.

Anti-ZCWCC1 antibody - ab203062 from Abcam

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ZCWCC1 antibody (ab203062) at 1/200 dilutionLane 1 : Rat testis lysatesLane 2 : Rat brain lysates

Anti-ZCWCC1 antibody - ab14429 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ZCWCC1 antibody - ab17965 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-ZCWCC1 antibody - ab191242 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-ZCWCC1 antibody (ab191242) at 1/1000 dilutionLane 1 : Jurkat cell lysateLane 2 : U-251 MG cell lysateLysates/proteins at 35 µg per lane.SecondaryGoat anti-rabbit IgG H&L (HRP) at 1/5000 dilution

Anti-MORC2 Antibody (aa600-700) - LS-C287075 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MORC2 Antibody (aa750-850) - LS-C91423 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MORC2 Antibody (aa600-700) - LS-C91424 from LifeSpan Bioscience

Prices $575.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MORC2 Antibody (aa750-850) - LS-C287077 from LifeSpan Bioscience

Prices $375.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-MORC2 Antibody (aa828-862) - LS-C344604 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Fluorescent image of U-87 MG cells stained with MORC2 Antibody. Antibody was diluted at 1:25 dilution. An Alexa Fluor 488-conjugated goat anti-rabbit lgG at 1:400 dilution was used as the secondary antibody (green). Cytoplasmic actin was counterstained with Alexa Fluor 555 conjugated with Phalloidin (red).

MORC2 Antibody - NBP1-89295 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: MORC2 Antibody [NBP1-89295] - Immunofluorescent staining of human cell line U-251 MG shows localization to nucleoplasm.

MORC2 Antibody - NB600-236 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MORC2 Antibody [NB600-236] - Samples : Nuclear extract (NE; 10 ug for WB; 1 mg for IP) from HeLa cells. Antibody : Affinity purified rabbit anti-ZCWCC1 antibody BL993 and 4 ug/mg lysate for immunoprecipitation. ZCWCC1 was also immunoprecipitated using affinity purified rabbit anti-ZCWCC1 antibody BL994 using 4 ug/mg lysate. Detection : Chemiluminescence with an exposure time of 3 minutes.

MORC2 Antibody - NB600-237 from Novus Biologicals

Prices $359.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: MORC2 Antibody [NB600-237] - Samples : Nuclear extract (NE; 10 ug for WB; 1 mg for IP) from HeLa cells. Antibody : ZCWCC1 was also immunoprecipitated with affinity purified rabbit anti-ZCWCC1 antibodies using 4 ug/mg lysate. Immunoprecipitated ZCWCC1 was detected by Western Blot using affinity purified rabbit anti-ZCWCC1 antibody at 0.2 ug/ml for WB. Detection : Chemiluminescence with an exposure time of 3 minutes.

MORC2 Antibody - H00022880-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: MORC2 Antibody [H00022880-B01] - analysis of MORC2 expression in transfected 293T cell line by MORC2 MaxPab polyclonal antibody (B01). Lane 1: MORC2 transfected lysate (110.70 KDa). Lane 2: Non-transfected lysate.

ZCWCC1 Polyclonal Antibody - bs-0354R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded human colon cancer labeled with Anti-EDG4/LPA2 Polyclonal Antibody, Unconjugated (bs-2881R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

ZCWCC1 (Ser739) Polyclonal Antibody - bs-10016R from Bioss

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin embedded rat placenta labeled with Rabbit Anti phospho-ZCWCC1 (Ser739) Polyclonal Antibody, Unconjugated (bs-10016R) at 1:200 followed by conjugation to the secondary antibody and DAB staining

ZCWCC1 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-0354R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZCWCC1 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-0354R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZCWCC1 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-0354R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZCWCC1 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-0354R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

ZCWCC1 Polyclonal Antibody, Cy3 Conjugated - bs-0354R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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