Gene Symbol | SLC35D2 |
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Entrez Gene | 11046 |
Alt Symbol | HFRC1, SQV7L, UGTrel8, hfrc |
Species | Human |
Gene Type | protein-coding |
Description | solute carrier family 35 (UDP-GlcNAc/UDP-glucose transporter), member D2 |
Other Description | SQV7-like protein|UDP-N-acetylglucosamine transporter|UDP-N-acetylglucosamine/UDP-glucose/GDP-mannose transporter|UDP-galactose transporter-related protein 8|fringe connection|homolog of Fringe connection protein 1|solute carrier family 35, member D2 |
Swissprots | O95454 Q498C1 Q7Z5X5 Q75W21 Q76EJ3 |
Accessions | EAW92646 EAW92647 Q76EJ3 AB106537 BAD14396 AB122077 BAC99016 AJ005866 CAA06743 AK024841 AK307890 BC009413 AAH09413 BC015146 BC100278 AAI00279 BC113579 AAI13580 BX361048 DB547513 HQ258608 ADR83361 XM_005251673 XP_005251730 XM_005251674 XP_005251731 XM_005251675 XP_005251732 XM_005251676 XP_005251733 XM_005251678 XP_005251735 XM_006716939 XP_006717002 XM_011518164 XP_011516466 XM_011518165 XP_011516467 XR_929705 NM_001286990 NP_001273919 NM_007001 NP_008932 NR_104627 |
Function | Antiporter transporting nucleotide sugars such as UDP-N- acetylglucosamine (UDP-GlcNAc), UDP-glucose (UDP-Glc) and GDP- mannose (GDP-Man) pooled in the cytosol into the lumen of the Golgi in exchange for the corresponding nucleosides monophosphates (UMP for UDP-sugars and GMP for GDP-sugars). May take part in heparan sulfate synthesis by supplying UDP-Glc-NAc, the donor substrate, and thus be involved in growth factor signaling. {ECO:0000269|PubMed:15082721, ECO:0000269|PubMed:15607426}. |
Subcellular Location | Golgi apparatus membrane {ECO:0000269|PubMed:15082721, ECO:0000269|PubMed:15607426}; Multi- pass membrane protein {ECO:0000269|PubMed:15082721, ECO:0000269|PubMed:15607426}. |
Tissue Specificity | Highly expressed in heart, kidney, small intestine, placenta, lung and peripheral blood leukocyte. Weakly expressed in skeletal muscle and spleen. Not expressed in brain, colon and thymus. {ECO:0000269|PubMed:15607426}. |
SLC35D2 (C-14) - sc-165497 from Santa Cruz Biotechnology
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Anti-SLC35D2 antibody - ab56850 from Abcam
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Anti-SLC35D2 antibody - C-terminal - ab190170 from Abcam
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Anti-SLC35D2 Antibody (C-Terminus) - LS-C169841 from LifeSpan Bioscience
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Anti-SLC35D2 Antibody (C-Terminus) IHC-plus⢠- LS-B9641 from LifeSpan Bioscience
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SLC35D2 Antibody - NBP2-38040 from Novus Biologicals
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SLC35D2 Antibody (1H5) - H00011046-M03 from Novus Biologicals
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Monoclonal Anti-SLC35D2 antibody produced in mouse - WH0011046M3 from Sigma-Aldrich
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Anti-SLC35D2 antibody produced in rabbit - SAB3500690 from Sigma-Aldrich
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SLC35D2 Antibody - C-terminal region (ARP66949_P050) - ARP66949_P050 from Aviva Systems Biology
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SLC35D2 antibody - orb75680 from Biorbyt
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SLC35D2 / UGTREL8 (C-term) antibody - AP55566PU-N from Acris Antibodies
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SLC35D2 / UGTREL8 antibody - H00011046-M03 from Acris Antibodies
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SLC35D2 Antibody - 6545 from ProSci
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SLC35D2 Antibody - 25374 from Signalway Antibody
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Anti-SLC35D2 (C-terminal) polyclonal antibody - DPAB-DC339 from Creative Diagnostics
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Anti-SLC35D2 (C-terminal) polyclonal antibody - DPAB-L21141 from Creative Diagnostics
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SLC35D2, Polyclonal Antibody - MBS248513 from MyBioSource
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SLC35D2, Polyclonal Antibody - MBS151008 from MyBioSource
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Anti-solute carrier family 35, member D2 - 08A011046 from MP Biomedicals
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SLC35D2 Antibody - 600-401-EP4 from Rockland Immunochemicals Inc
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SLC35D2 (C-Terminus) antibody - pab76247 from Covalab
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Anti-SLC35D2-Antibody-C-Terminus-ALS15890 - ALS15890 from Abgent, a WuXi AppTec company
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SLC35D2, Polyclonal Antibody - MBS9414729 from MyBioSource
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Anti-SLC35D2 antibody produced in rabbit - HPA064047 from Sigma-Aldrich
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