ALS2CL

Gene Symbol ALS2CL
Entrez Gene 259173
Alt Symbol RN49018
Species Human
Gene Type protein-coding
Description ALS2 C-terminal like
Other Description ALS2 C-terminal-like protein
Swissprots Q8N9U1 Q6ZNC5 Q6AI56 Q86YD2 Q6ZTL4 Q32MA1 Q8NAL7 Q60I27 Q6ZNC7
Accessions AAK13665 EAW64775 EAW64776 EAW64777 EAW64778 EAW64779 EAW64780 Q60I27 AB107015 BAD51817 AK074118 BAB84944 AK092455 BAC03895 AK093844 BAC04237 AK096091 AK097225 AK126505 BAC86572 AK131270 BAD18448 AK131273 BAD18450 AL832132 AL832203 AL833107 BC042906 AAH42906 BC061883 AAH61883 BC075825 AAH75825 BC109233 AAI09234 BC156525 AAI56526 BC172558 AAI72558 BU685010 CR627258 CAH10367 DA242202 DB350037 XM_005265025 XP_005265082 XM_006713091 XP_006713154 XM_006713093 XP_006713156 XM_006713094 XP_006713157 XM_011533572 XP_011531874 XM_011533573 XP_011531875 XR_427263 XR_427264 XR_427265 XR_940405 XR_940406 XR_940407 XR_940408 XR_940409 XR_940410 XR_940411 XR_940412 NM_001190707 NP_001177636 NM_147129 NP_667340 NM_182775 NP_877576 NR_033815
Function Acts as a guanine nucleotide exchange factor (GEF) for Rab5 GTPase. Regulates the ALS2-mediated endosome dynamics. {ECO:0000269|PubMed:15388334, ECO:0000269|PubMed:16473597, ECO:0000269|PubMed:17239822}.
Subcellular Location Cytoplasm {ECO:0000269|PubMed:15388334, ECO:0000269|PubMed:17239822}. Note=Distributed onto the vesicular compartments in the cytoplasm with strong punctated staining. Colocalizes with RAB5A onto the vesicular/membranous compartments in the cytoplasm, particularly to the leading edges of the cells.
Tissue Specificity Expressed in heart and kidney. {ECO:0000269|PubMed:15388334}.

ALS2CL CRISPR/Cas9 KO Plasmid (h) - sc-417873 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALS2CL HDR Plasmid (h) - sc-417873-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALS2CL Double Nickase Plasmid (h) - sc-417873-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALS2CL Double Nickase Plasmid (h2) - sc-417873-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALS2CL CRISPR Activation Plasmid (h) - sc-417873-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALS2CL CRISPR Activation Plasmid (h2) - sc-417873-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALS2CL Lentiviral Activation Particles (h) - sc-417873-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALS2CL Lentiviral Activation Particles (h2) - sc-417873-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

ALS2CL siRNA (h) - sc-60156 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ALS2CL shRNA Plasmid (h) - sc-60156-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

ALS2CL shRNA (h) Lentiviral Particles - sc-60156-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU092091 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN3090 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3090 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR10672 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr10672

ALS2CL siRNA (Human) - CRJ6797 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

ALS2CL - MBS8209569 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human ALS2CL (NM_182775.2) - SHH235522 from Creative biogene

Category siRNA
Species Reactivities Human

ALS2CL shRNA Plasmid (Human) - CHJ6797 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

ALS2CL miRNA 3'UTR clone - MiUTR3H-12416 from Creative biogene

Species Reactivities Human

ALS2CL miRNA 3'UTR clone - MiUTR3H-12417 from Creative biogene

Species Reactivities Human
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