MCCC2

Gene Symbol MCCC2
Entrez Gene 64087
Alt Symbol MCCB
Species Human
Gene Type protein-coding
Description methylcrotonoyl-CoA carboxylase 2 (beta)
Other Description 3-methylcrotonyl-CoA carboxylase 2|3-methylcrotonyl-CoA carboxylase non-biotin-containing subunit|3-methylcrotonyl-CoA:carbon dioxide ligase subunit beta|MCCase subunit beta|biotin carboxylase|methylcrotonoyl-CoA carboxylase beta chain, mitochondrial|methylcrotonoyl-Coenzyme A carboxylase 2 (beta)|non-biotin containing subunit of 3-methylcrotonyl-CoA carboxylase
Swissprots Q9Y4L7 Q96C27 Q9HCC0 A6NIY9
Accessions BAB41121 EAW95691 EAW95692 EAW95693 Q9HCC0 AB050049 BAB16880 AF261884 AAK49409 AF301000 AAK16404 AF310971 AAG53094 AK025591 AK090834 BAG52236 AK310194 AL079298 CAB45194 BC014897 AAH14897 BC065027 AAH65027 CN309723 XM_005248567 XP_005248624 XM_011543528 XP_011541830 XM_011543529 XP_011541831 NM_022132 NP_071415
Function Carboxyltransferase subunit of the 3-methylcrotonyl-CoA carboxylase, an enzyme that catalyzes the conversion of 3- methylcrotonyl-CoA to 3-methylglutaconyl-CoA, a critical step for leucine and isovaleric acid catabolism. {ECO:0000269|PubMed:17360195}.
Subcellular Location Mitochondrion matrix {ECO:0000269|PubMed:11170888, ECO:0000269|PubMed:16023992}.
Top Pathways Valine, leucine and isoleucine degradation

MCCB (B-1) - sc-390836 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
MCCB (B-1): sc-390836. Western blot analysis of MCCB expression in Hep G2 (A) and NCI-H292 (B) whole cell lysates.

MCCB (C-20) - sc-50738 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

MCCB (H-300) - sc-366942 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Rabbit
Clonality Polyclonal
MCCB (H-300): sc-366942. Western blot analysis of MCCB expression in Hep G2 (A) and NCI-H292 (B) whole cell lysates.

MCCB (N-18) - sc-50740 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-MCCC2 antibody - ab155770 from Abcam

Host Rabbit
Clonality Polyclonal
Anti-MCCC2 antibody (ab155770) at 1/1000 dilution + HepG2 whole cell lysate at 30 µg

Anti-MCCC2 antibody - ab197297 from Abcam

Prices $370.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-MCCC2 antibody (ab197297) at 1/500 dilutionLane 1 : K562 lysateLane 2 : A549 lysateLane 3 : HeLa lysate

Anti-MCCC2 antibody - ab91414 from Abcam

Prices $304.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-MCCC2 antibody (ab91414) at 1/100 dilution + 293 cell line lysates at 35 µg

Anti-MCCC2 antibody - ab118370 from Abcam

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
All lanes : Anti-MCCC2 antibody (ab118370) at 5 µg/mlLane 1 : MCCC2 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 25 µg per lane.

Anti-MCCC2 antibody - ab69173 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Anti-MCCC2 antibody (ab69173) at 1/500 dilution + Human liver tissue lysate at 25 µgSecondaryGoat Anti-Mouse IgG (H&L)-HRP at 1/2500 dilution

Anti-MCCC2 antibody - C-terminal - ab139145 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-MCCC2 antibody - C-terminal (ab139145) at 1/100 dilution + NCI-H292 cell line lysates at 35 µgdeveloped using the ECL technique

Anti-MCCC2 / MCCB Antibody (aa468-496, AP) - LS-C237479 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCCC2 / MCCB Antibody (aa468-496, FITC) - LS-C237482 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCCC2 / MCCB Antibody (aa468-496, PE) - LS-C237483 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCCC2 / MCCB Antibody (aa468-496, Biotin) - LS-C237481 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCCC2 / MCCB Antibody (aa468-496, APC) - LS-C237480 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCCC2 / MCCB Antibody (Internal, APC) - LS-C245006 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCCC2 / MCCB Antibody (Internal, AP) - LS-C245005 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCCC2 / MCCB Antibody (Internal, FITC) - LS-C245009 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCCC2 / MCCB Antibody (Internal, Azide-free, HRP) - LS-C247698 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCCC2 / MCCB Antibody (Internal, Biotin) - LS-C245008 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCCC2 / MCCB Antibody (Internal, PE) - LS-C245010 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCCC2 / MCCB Antibody (aa468-496, Azide-free, HRP) - LS-C248783 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCCC2 / MCCB Antibody - LS-C308913 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-MCCC2 / MCCB Antibody (aa468-496) - LS-C322903 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-MCCC2 / MCCB Antibody - LS-C310961 from LifeSpan Bioscience

Prices $475.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
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