CLSPN

Gene Symbol CLSPN
Entrez Gene 63967
Alt Symbol -
Species Human
Gene Type protein-coding
Description claspin
Other Description claspin homolog|hClaspin
Swissprots Q5VYG0 Q8IWI1 Q2KHM3 A6NFL4 Q6P6H5 Q1RMC6 Q9HAW4
Accessions EAX07401 EAX07402 Q9HAW4 AF297866 AAG24515 AK308193 BC018670 AAH18670 BC038991 AAH38991 BC062215 AAH62215 BC113116 AAI13117 BC115023 BC115024 BC115025 AAI15026 BC115026 AAI15027 BC115027 BC137279 AAI37280 BC140789 AAI40790 BG109920 XM_011541938 XP_011540240 XM_011541939 XP_011540241 XM_011541940 XP_011540242 XM_011541941 XP_011540243 XM_011541942 XP_011540244 XM_011541943 XP_011540245 NM_001190481 NP_001177410 NM_022111 NP_071394
Function Required for checkpoint mediated cell cycle arrest in response to inhibition of DNA replication or to DNA damage induced by both ionizing and UV irradiation. Adapter protein which binds to BRCA1 and the checkpoint kinase CHEK1 and facilitates the ATR- dependent phosphorylation of both proteins. Can also bind specifically to branched DNA structures and may associate with S- phase chromatin following formation of the pre-replication complex (pre-RC). This may indicate a role for this protein as a sensor which monitors the integrity of DNA replication forks. {ECO:0000269|PubMed:12766152, ECO:0000269|PubMed:15096610, ECO:0000269|PubMed:15190204, ECO:0000269|PubMed:15226314, ECO:0000269|PubMed:15707391}.
Subcellular Location Nucleus {ECO:0000269|PubMed:12766152}.

Human Claspin peptide - ab94830 from Abcam

Category Peptide

Human Claspin protein fragment - ab125977 from Abcam

Category Protein
Source E. coli
Species Human

CLSPN fusion protein - ag19637 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

CLSPN fusion protein - ag19650 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human Claspin(CLSPN) ,partial - CSB-YP888014HU CSB-EP888014HU CSB-BP888014HU CSB-MP888014HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

CLASPIN Blocking Peptide (OESA09433) - OESA09433 from Aviva Systems Biology

Category Peptide
Prices $245.00
Sizes 50 µg
Species Human

CLSPN Peptide, Human - M34GP03318H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Claspin Recombinant Protein Antigen - NBP2-55291PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

Claspin (CLSPN), partial, Recombinant Protein - MBS1348632 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Claspin Recombinant Protein Antigen - NBP2-55290PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human
Search more