KIAA0196

Gene Symbol KIAA0196
Entrez Gene 9897
Alt Symbol RTSC, SPG8
Species Human
Gene Type protein-coding
Description KIAA0196
Other Description WASH complex subunit strumpellin|strumpellin
Swissprots Q8TBQ2 A8K4R7 Q12768 Q3KQX5
Accessions EAW92080 EAW92081 EAW92082 Q12768 AI266595 AK223628 BAD97348 AK291032 BAF83721 AK296970 BAG59514 BC026951 AAH26951 BC106015 AAI06016 D83780 BAA12109 DA185885 XM_005251120 XP_005251177 XM_011517409 XP_011515711 XM_011517410 XP_011515712 NM_014846 NP_055661
Function Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting (PubMed:19922875, PubMed:20498093). May be involved in axonal outgrowth. Involved in cellular localization of ADRB2 (PubMed:23085491). Involved in cellular trafficking of BLOC-1 complex cargos such as ATP7A and VAMP7 (PubMed:23676666). {ECO:0000269|PubMed:19922875, ECO:0000269|PubMed:20833645, ECO:0000269|PubMed:23085491, ECO:0000269|PubMed:23676666}.
Subcellular Location Cytoplasm, cytosol {ECO:0000269|PubMed:20833645}. Endoplasmic reticulum {ECO:0000269|PubMed:20833645}. Early endosome {ECO:0000269|PubMed:23085491, ECO:0000269|PubMed:23676666}. Note=Colocalizes with SYP/synaptophysin in the external molecular layer of the dentate gyrus and in motoneurons of the ventral horn of spinal cord. {ECO:0000269|PubMed:20833645}.
Tissue Specificity Expressed ubiquitously. {ECO:0000269|PubMed:20833645}.

WASH complex subunit strumpellin (KIAA0196), Human, ELISA Kit - CSB-EL012174HU from ARP American Research Products

Category ELISA Kit
Prices $495.00, $695.00, $696.00, $699.00
Sizes 48 t, 96 t, 5 x 96t, 10 x 96t

Strumpellin (STRUM), ELISA Kit - MBS9312360 from MyBioSource

Category ELISA Kit
Prices $435.00, $600.00, $2,650.00, $5,205.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

WASH complex subunit strumpellin, ELISA Kit - MBS280679 from MyBioSource

Category ELISA Kit
Prices $425.00, $720.00, $3,160.00, $6,055.00
Sizes 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells

Human WASH complex subunit strumpellin(KIAA0196) ELISA kit - CSB-EL012174HU from Cusabio

Category ELISA Kit
Sensitivity 4.69 pg/ml.
Range 18.75 pg/ml-1200 pg/ml

KIAA0196, ELISA Kit - MBS908675 from MyBioSource

Category ELISA Kit
Prices $250.00, $495.00, $710.00, $2,705.00, $5,145.00
Sizes 24 -strip-wells (Limit 1), 48 -strip-wells, 96 -strip-wells, 5x96-strip-wells, 10x96-strip-wells
Sensitivity 4.69 pg/ml
Range 18.75 pg/ml-1200 pg/ml

Human WASH complex subunit strumpellin (KIAA0196) ELISA Kit - EKC36054 from Biomatik

Category ELISA Kit
Prices $705.00, $2,820.00, $5,288.00
Sizes 96 t, 5x96t, 10x96t
Sensitivity 4.69 pg/ml
Range 18.75 pg/ml-1200 pg/ml

Human KIAA0196 ELISA Kit - E021650 from Biobool

Category ELISA Kit
Sensitivity 4.69 pg/ml

WASHC5 ELISA Kit (Human) (OKCA01592) - OKCA01592 from Aviva Systems Biology

Category ELISA Kit
Prices $600.00
Sizes 96 wells
Sensitivity 4.69 pg/mL
Range 18.75 - 1,200 pg/mL
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