Gene Symbol | DPYS |
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Entrez Gene | 1807 |
Alt Symbol | DHP, DHPase |
Species | Human |
Gene Type | protein-coding |
Description | dihydropyrimidinase |
Other Description | dihydropyrimidine amidohydrolase|hydantoinase |
Swissprots | Q14117 |
Accessions | BAA33067 CAH05690 EAW91893 Q14117 AK311261 BC034395 AAH34395 D78011 BAA11189 JF432195 ADZ15412 XM_005250818 XP_005250875 XM_006716518 XP_006716581 XM_011516903 XP_011515205 XM_011516904 XP_011515206 NM_001385 NP_001376 |
Function | Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6- dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate. |
Tissue Specificity | Liver and kidney. |
Top Pathways | Drug metabolism - other enzymes, Pyrimidine metabolism, beta-Alanine metabolism, Pantothenate and CoA biosynthesis |
DPYS-Over-expression-Lysate - LY12545a from Abgent, a WuXi AppTec company
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DPYS overexpression lysate - LY419991 from Acris Antibodies
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DPYS 293 Cell Lysate - 409360 from ABBIOTEC
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DPYS Overexpression Lysate (Native) - NBL1-10008 from Novus Biologicals
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DPYS (h): 293T Lysate - sc-114343 from Santa Cruz Biotechnology
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DPYS Over-expression Lysate Product - GWB-603D57 from Genway Biotech
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Human DPYS / Dihydropyrimidinase Insect Cell Lysate (WB positive control) - 14884-HNCBL-300 from Sino Biological
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Human DPYS / Dihydropyrimidinase Insect Cell Lysate (WB positive control) - 14884-H20BL-300 from Sino Biological
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Human DPYS Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175324 from Biorbyt
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Human DPYS Baculovirus-Insect Cells Transfected Lysate (positive control) (denatured) - orb175323 from Biorbyt
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Panoply™ Human DPYS Knockdown Stable Cell Line - CSC-DC004533 from Creative biogene
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