Gene Symbol | DPYS |
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Entrez Gene | 1807 |
Alt Symbol | DHP, DHPase |
Species | Human |
Gene Type | protein-coding |
Description | dihydropyrimidinase |
Other Description | dihydropyrimidine amidohydrolase|hydantoinase |
Swissprots | Q14117 |
Accessions | BAA33067 CAH05690 EAW91893 Q14117 AK311261 BC034395 AAH34395 D78011 BAA11189 JF432195 ADZ15412 XM_005250818 XP_005250875 XM_006716518 XP_006716581 XM_011516903 XP_011515205 XM_011516904 XP_011515206 NM_001385 NP_001376 |
Function | Catalyzes the second step of the reductive pyrimidine degradation, the reversible hydrolytic ring opening of dihydropyrimidines. Can catalyze the ring opening of 5,6- dihydrouracil to N-carbamyl-alanine and of 5,6-dihydrothymine to N-carbamyl-amino isobutyrate. |
Tissue Specificity | Liver and kidney. |
Top Pathways | Drug metabolism - other enzymes, Pyrimidine metabolism, beta-Alanine metabolism, Pantothenate and CoA biosynthesis |
Human Dihydropyrimidinase protein fragment - ab158312 from Abcam
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DPYS / Dihydropyrimidinase Antibody Blocking Peptide - LS-E2423 from LifeSpan Bioscience
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DPYS / Dihydropyrimidinase Antibody Blocking Peptide - LS-E15263 from LifeSpan Bioscience
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DPYS / Dihydropyrimidinase Antibody Blocking Peptide - LS-E15264 from LifeSpan Bioscience
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Recombinant Human DPYS Protein - H00001807-Q01 from Novus Biologicals
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DPYS-Antibody-C-term-Blocking-peptide - BP13434b from Abgent, a WuXi AppTec company
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DPYS Protein Lysate (APL10426) - APL10426 from Aviva Systems Biology
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Human DPYS protein (GST Tag) - orb138714 from Biorbyt
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DPYS Blocking Peptide - 33R-9643 from Fitzgerald
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DPYS Blocking Peptide - 33R-5375 from Fitzgerald
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DPYS - H00001807-Q01-10 from Acris Antibodies
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DPYS - H00001807-Q01-25 from Acris Antibodies
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DPYS fusion protein - ag6925 from Proteintech Group
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DPYS fusion protein - ag3972 from Proteintech Group
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Recombinant Human DPYS, His-tagged - DPYS-12157H from Creative Biomart
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Recombinant Human DPYS, Gly&Pro tagged - DPYS-242H from Creative Biomart
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Recombinant Human DPYS, His-GST tagged - DPYS-243H from Creative Biomart
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Recombinant Dihydropyrimidinase (DPYS) - RPE669Hu01 from Uscn Life Science Inc.
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Human DPYS / Dihydropyrimidinase Protein (His & GST Tag) - 14884-H20B-20 from Sino Biological
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Human DPYS / Dihydropyrimidinase Protein - 14884-HNCB-50 from Sino Biological
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Recombinant Dihydropyrimidinase (DPYS) - RPE669Hu01 from Cloud-clone
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Recombinant Pseudomonas aeruginosa D-hydantoinase/dihydropyrimidinase(dht) - CSB-YP881232EZX CSB-EP881232EZX CSB-BP881232EZX CSB-MP881232EZX from Cusabio
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Recombinant Pseudomonas putida D-hydantoinase/dihydropyrimidinase(dht) - CSB-YP701566FFZ CSB-EP701566FFZ CSB-BP701566FFZ CSB-MP701566FFZ from Cusabio
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Recombinant Human Dihydropyrimidinase(DPYS) - CSB-YP007169HU CSB-EP007169HU CSB-BP007169HU CSB-MP007169HU from Cusabio
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DPYS - TP306603 from Acris Antibodies
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