NCOA3

Gene Symbol	NCOA3
Entrez Gene	8202
Alt Symbol	ACTR, AIB-1, AIB1, CAGH16, CTG26, KAT13B, RAC3, SRC-3, SRC3, TNRC14, TNRC16, TRAM-1, bHLHe42, pCIP
Species	Human
Gene Type	protein-coding
Description	nuclear receptor coactivator 3
Other Description	CBP-interacting protein|amplified in breast cancer 1 protein|class E basic helix-loop-helix protein 42|receptor-associated coactivator 3|steroid receptor coactivator protein 3|thyroid hormone receptor activator molecule 1
Swissprots	Q9BR49 Q9UPG7 Q0VF45 Q9Y6Q9 Q5JYD9 Q9UPG4 A4LAZ5 Q5JYE0 Q9UPC9
Accessions	ABO43042 EAW75696 EAW75697 EAW75698 EAW75699 EAW75700 EAW75701 EAW75702 Q9Y6Q9 AB209863 BAD93100 AF010227 AAC51663 AF012108 AAC51677 AF016031 AAC51849 AF036892 AAB92368 AK289683 BAF82372 AK296810 BAG59383 AK302588 BAG63841 AK302595 BAG63847 AK308346 BC092516 AAH92516 BC119001 AAI19002 BC122547 AAI22548 BM692321 BU588121 CA450268 DB091786 NM_001174087 NP_001167558 NM_001174088 NP_001167559 NM_006534 NP_006525 NM_181659 NP_858045
Function	Nuclear receptor coactivator that directly binds nuclear receptors and stimulates the transcriptional activities in a hormone-dependent fashion. Plays a central role in creating a multisubunit coactivator complex, which probably acts via remodeling of chromatin. Involved in the coactivation of different nuclear receptors, such as for steroids (GR and ER), retinoids (RARs and RXRs), thyroid hormone (TRs), vitamin D3 (VDR) and prostanoids (PPARs). Displays histone acetyltransferase activity. Also involved in the coactivation of the NF-kappa-B pathway via its interaction with the NFKB1 subunit.
Subcellular Location	Cytoplasm. Nucleus. Note=Mainly cytoplasmic and weakly nuclear. Upon TNF activation and subsequent phosphorylation, it translocates from the cytoplasm to the nucleus.
Tissue Specificity	Widely expressed. High expression in heart, skeletal muscle, pancreas and placenta. Low expression in brain, and very low in lung, liver and kidney.

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human SRC3 protein fragment - ab159961 from Abcam Category Protein Source Wheat germ Species Human

SRC3 peptide - ab4915 from Abcam Category Peptide

NCOA3 / SRC-3 / AIB1 Antibody Blocking Peptide - LS-E11392 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NCOA3 / SRC-3 / AIB1 Antibody Blocking Peptide - LS-E11393 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

NCOA3 / SRC-3 / AIB1 Antibody Blocking Peptide - LS-E26668 from LifeSpan Bioscience Category Peptide Prices $145.00 Sizes 100 µg

Recombinant Human NCOA3/AIB1 Protein - H00008202-Q01 from Novus Biologicals Category Protein Prices $369.00, $529.00 Sizes 10 µg, 25 µg Source Wheat Germ Species Human

NCOA3 - H00008202-Q01-10 from Acris Antibodies Category Protein Prices $380.00 Sizes 10 µg Source in vitro transl. Species Human

NCOA3 - H00008202-Q01-25 from Acris Antibodies Category Protein Prices $500.00 Sizes 25 µg Source in vitro transl. Species Human

NCOA3 - H00023471-P01-02 from Acris Antibodies Category Protein Prices $310.00 Sizes 2 µg Source in vitro transl. Species Human

NCOA3 control peptide - SP5313CP from Acris Antibodies Category Peptide Prices $205.00 Sizes 50 µg

NCOA3 fusion protein - ag18434 from Proteintech Group Category Protein Source E. coli-derived, PGEX-4T Species Human

NCOA3 fusion protein - ag18424 from Proteintech Group Category Protein Source E. coli-derived, PET28a Species Human

Recombinant Human RAC3, His-tagged - NCOA3-7035H from Creative Biomart Category Protein Source E. coli Species Human

Recombinant Human NCOA3, GST-tagged - NCOA3-121H from Creative Biomart Category Protein Source Wheat germ Species Human

Recombinant Nuclear Receptor Coactivator 3 (NCOA3) - RPE798Hu01 from Uscn Life Science Inc. Category Protein Source E.coli Species Human

Recombinant Nuclear Receptor Coactivator 3 (NCOA3) - RPE798Ra01 from Uscn Life Science Inc. Category Protein Source E.coli Species Rat

NCoA-3 (S587) Peptide - BS3516P from Bioworld Technology Category Peptide Prices $158.00 Sizes 100 µl

Recombinant Human Nuclear receptor coactivator 3(NCOA3) ,partial - CSB-YP015541HU CSB-EP015541HU CSB-BP015541HU CSB-MP015541HU from Cusabio Category Protein Source Yeast or E.coli or Baculovirus or Mammalian cell Species Human

Nuclear Receptor Coactivator 3 Protein (Recombinant) - abx168210 from Abbexa Category Protein Source Human Species Human

NCOA3/AIB1 Recombinant Protein Antigen - NBP1-90256PEP from Novus Biologicals Category Protein Prices $199.00 Sizes 100 µl Source E.coli Species Human

SRC3 Blocking Peptide (OESA09491) - OESA09491 from Aviva Systems Biology Category Peptide Prices $245.00 Sizes 50 µg Species Human

SRC3 BLOCKING PEPTIDE (OESA09492) - OESA09492 from Aviva Systems Biology Category Peptide Prices $245.00 Sizes 50 µg Species Human

AIB1-RAC3NCOA3-Antibody-C-term-Blocking-peptide - BP1082b from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

AIB1-RAC3NCOA3-Antibody-Center-Blocking-peptide - BP1082a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

NCOA3-Blocking-Peptide-N-term - BP19843a from Abgent, a WuXi AppTec company Category Peptide Prices $80.00 Sizes 100 µg

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