Gene Symbol | CC2D2A |
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Entrez Gene | 57545 |
Alt Symbol | JBTS9, MKS6 |
Species | Human |
Gene Type | protein-coding |
Description | coiled-coil and C2 domain containing 2A |
Other Description | coiled-coil and C2 domain-containing protein 2A |
Swissprots | E9PEV5 Q3SYP3 E7EP21 D6RB72 Q9H8A7 Q9P2K1 B3FW08 A6ND97 |
Accessions | CCQ43067 EAW92734 Q9P2K1 AA441801 AB037766 BAA92583 AB384183 BAG10039 AI376394 AK023876 BAB14710 AK025543 AK096047 AK309178 BC053865 BC061921 BC070395 BC103710 AAI03711 BX647334 CF528984 DA860072 DB043556 EU450799 ACC96081 N35522 XM_005248177 XP_005248234 XM_011513869 XP_011512171 XM_011513870 XP_011512172 XM_011513871 XP_011512173 XM_011513872 XP_011512174 XM_011513873 XP_011512175 XM_011513874 XP_011512176 NM_001080522 NP_001073991 NM_001164720 NP_001158192 NM_020785 NP_065836 |
Function | Component of the tectonic-like complex, a complex localized at the transition zone of primary cilia and acting as a barrier that prevents diffusion of transmembrane proteins between the cilia and plasma membranes. Required for ciliogenesis and sonic hedgehog/SHH signaling (By similarity). {ECO:0000250}. |
Subcellular Location | Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body. Note=Localizes at the transition zone, a region between the basal body and the ciliary axoneme. {ECO:0000250}. |
Tissue Specificity | Strongly expressed in prostate, pancreas, kidney, lung, liver, retina, kidney, fetal brain and fetal kidney. Lower expression in spleen, small intestine, colon, skeletal muscle, ovary, thymus and heart. {ECO:0000269|PubMed:18387594, ECO:0000269|PubMed:18950740}. |
Anti-CC2D2A antibody - ab151210 from Abcam
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Anti-CC2D2A Antibody (aa20-69) - LS-C152024 from LifeSpan Bioscience
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CC2D2A Antibody - NBP1-93673 from Novus Biologicals
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Anti-CC2D2A antibody produced in rabbit - HPA044124 from Sigma-Aldrich
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CC2D2A Antibody - N-terminal region (ARP65635_P050) - ARP65635_P050 from Aviva Systems Biology
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CC2D2A antibody - 22293-1-AP from Acris Antibodies
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CC2D2A antibody - 22293-1-AP from Proteintech Group
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CC2D2A, Polyclonal Antibody - MBS2517565 from MyBioSource
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CC2D2A Antibody - EPP11193 from Elabscience
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Anti-CC2D2A (aa 659-767) polyclonal antibody - DPABH-03341 from Creative Diagnostics
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CC2D2A antibody - TA338019 from Acris Antibodies
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anti-CC2D2A antibody - A001337 from Biobool
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Anti-CC2D2A Antibody A05681 - A05681 from Boster Bio
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CC2D2A, Polyclonal Antibody - MBS767569 from MyBioSource
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CC2D2A Antibody - N-terminal region : Biotin (ARP65635_P050-Biotin) - ARP65635_P050-Biotin from Aviva Systems Biology
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CC2D2A Antibody - N-terminal region : FITC (ARP65635_P050-FITC) - ARP65635_P050-FITC from Aviva Systems Biology
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CC2D2A Antibody - N-terminal region : HRP (ARP65635_P050-HRP) - ARP65635_P050-HRP from Aviva Systems Biology
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Anti-CC2D2A Antibody (aa20-69, FITC) - LS-C473301 from LifeSpan Bioscience
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Anti-CC2D2A Antibody (aa20-69, HRP) - LS-C473302 from LifeSpan Bioscience
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Anti-CC2D2A Antibody (aa20-69, Biotin) - LS-C473298 from LifeSpan Bioscience
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