VPS26A

Gene Symbol VPS26A
Entrez Gene 9559
Alt Symbol HB58, Hbeta58, PEP8A, VPS26
Species Human
Gene Type protein-coding
Description vacuolar protein sorting 26 homolog A (S. pombe)
Other Description vacuolar protein sorting-associated protein 26A|vesicle protein sorting 26A
Swissprots O75436 Q9H982 B2RDD3 Q8TBH4 A8MZ56
Accessions EAW54311 EAW54312 EAW54313 O75436 AF054179 AAC39912 AF175266 AAF89954 AK022992 BAB14351 AK290536 BAF83225 AK297142 BAG59643 AK309021 AK315496 BAG37880 AL110166 BC022505 AAH22505 BQ048905 BX647725 BX649092 CD358963 EU832481 ACE87653 EU832561 ACE86963 XM_011540378 XP_011538680 NM_001035260 NP_001030337 NM_004896 NP_004887
Function Acts as component of the retromer cargo-selective complex (CSC). The CSC is believed to be the core functional component of retromer or respective retromer complex variants acting to prevent missorting of selected transmembrane cargo proteins into the lysosomal degradation pathway. The recruitment of the CSC to the endosomal membrane involves RAB7A and SNX3. The SNX-BAR retromer mediates retrograde transport of cargo proteins from endosomes to the trans-Golgi network (TGN) and is involved in endosome-to-plasma membrane transport for cargo protein recycling. The SNX3-retromer mediates the retrograde endosome-to-TGN transport of WLS distinct from the SNX-BAR retromer pathway. The SNX27-retromer is believed to be involved in endosome-to-plasma membrane trafficking and recycling of a broad spectrum of cargo proteins (Probable). The CSC seems to act as recruitment hub for other proteins, such as the WASH complex and TBC1D5 (Probable). Required for retrograde transport of lysosomal enzyme re
Subcellular Location Cytoplasm. Endosome membrane; Peripheral membrane protein. Early endosome {ECO:0000269|PubMed:15078903}. Note=Localizes to tubular profiles adjacent to endosomes (PubMed:15078903). Predominantly found in early not late endosomes (By similarity). {ECO:0000250|UniProtKB:P40336}.

VPS26 (L-19) - sc-69128 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VPS26 (L-19): sc-69128. Western blot analysis of VPS26 expression in non-transfected: sc-117752 (A) and mouse VPS26 transfected: sc-124576 (B) 293T whole cell lysates.

VPS26 (V-13) - sc-69129 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VPS26 (V-13): sc-69129. Western blot analysis of VPS26 expression in non-transfected: sc-117752 (A) and mouse VPS26 transfected: sc-124576 (B) 293T whole cell lysates.

VPS26 (E-3) - sc-390304 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Mouse
Clonality Monoclonal
VPS26 (E-3): sc-390304. Western blot analysis of VPS26 expression in non-transfected: sc-117752 (A) and mouse VPS26 transfected: sc-124576 (B) 293T whole cell lysates.

VPS26 (A-14) - sc-69126 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VPS26 (A-14): sc-69126. Western blot analysis of VPS26 expression in mouse kidney (A), rat brain (B) and human liver (C) tissue extracts.

VPS26 (C-18) - sc-69127 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
VPS26 (C-18): sc-69127. Western blot analysis of VPS26 expression in non-transfected: sc-117752 (A) and mouse VPS26 transfected: sc-124576 (B) 293T whole cell lysates.

VPS26 (10L3) - sc-135606 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
VPS26 (10L3): sc-135606. Western blot analysis of VPS26 expression in human VPS26 transfected (A) and non-transfected (B) 293T whole cell lysates.

Anti-VPS26 antibody - ab23892 from Abcam

Prices $398.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-VPS26 antibody (ab23892) at 1 µg/mlLane 1 : Human kidney lysateLane 2 : Human kidney lysate with Human VPS26 peptide (ab24288) at 1 µg/mlLysates/proteins at 20 µg per lane.SecondaryAlexa Fluor Goat polyclonal to Rabbit IgG (700) at 1/10000 dilutionPerformed under reducing conditions.

Anti-VPS26 antibody - ab76169 from Abcam

Host Rabbit
Clonality Polyclonal
All lanes : Anti-VPS26 antibody (ab76169) at 1/1000 dilutionLane 1 : Rat brain lysatesLane 2 : Rat brain lysates + ab76169 pre-absorbed with Immunizing peptidePerformed under reducing conditions.

Anti-VPS26 antibody - ab84167 from Abcam

Host Sheep
Clonality Polyclonal

Anti-VPS26 antibody - ab93320 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-VPS26 antibody (ab93320) at 1/100 dilution + HepG2 cell line lysate at 35 µg

Anti-VPS26 antibody [EPR13455(B)] - N-terminal - ab180172 from Abcam

Prices $379.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13455(B)
All lanes : Anti-VPS26 antibody [EPR13455(B)] - N-terminal (ab180172) at 1/1000 dilutionLane 1 : HepG2 cell lysateLane 2 : HeLa cell lysateLane 3 : 293T cell lysateLysates/proteins at 10 µg per lane.SecondaryStandard HRP labeled goat anti-rabbit at 1/2000 dilutiondeveloped using the ECL technique

Anti-VPS26 antibody [EPR13456] - ab181352 from Abcam

Prices $385.00
Sizes 100 µl
Host Rabbit
Clonality Monoclonal
Clone EPR13456
All lanes : Anti-VPS26 antibody [EPR13456] (ab181352) at 1/1000 dilutionLane 1 : HepG2 cell lysateLane 2 : HeLa cell lysateLane 3 : 293T cell lysateLane 4 : A431 cell lysateLysates/proteins at 10 µg per lane.

Anti-VPS26A / VPS26 Antibody (Internal) - LS-C95274 from LifeSpan Bioscience

Prices $325.00
Sizes 500 µg
Host Rabbit
Clonality Polyclonal

Anti-VPS26A / VPS26 Antibody (Internal, AP) - LS-C284213 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VPS26A / VPS26 Antibody (Internal, APC) - LS-C284214 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VPS26A / VPS26 Antibody (Internal, Biotin) - LS-C284215 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VPS26A / VPS26 Antibody (Internal, FITC) - LS-C284216 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VPS26A / VPS26 Antibody (aa315-327) - LS-C55672 from LifeSpan Bioscience

Prices $395.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
Antibody staining (1 ug/ml) of Human Kidney lysate (RIPA buffer, 35 ug total protein per lane). Primary incubated for 1 hour. Detected by Western blot of chemiluminescence.

Anti-VPS26A / VPS26 Antibody (Internal, Azide-free, HRP) - LS-C284217 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VPS26A / VPS26 Antibody (Internal, PE) - LS-C284218 from LifeSpan Bioscience

Prices $515.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VPS26A / VPS26 Antibody (Internal) - LS-C329081 from LifeSpan Bioscience

Prices $425.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-VPS26A / VPS26 Antibody (C-Terminus) - LS-C145513 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
VPS26A / VPS26 antibody LS-C145513 Western blot of Fetal Kidney lysate. Antibody concentration 1 ug/ml.

Anti-VPS26A / VPS26 Antibody - LS-C137265 from LifeSpan Bioscience

Prices $255.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-VPS26A / VPS26 Antibody (aa263-291) - LS-C160537 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Formalin-fixed and paraffin-embedded human hepatocarcinoma reacted with VPS26A Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

VPS26 Antibody (CL2287) - NBP2-36754 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone CL2287
Western Blot: VPS26 Antibody (CL2287) [NBP2-36754] - Lane 1: Marker [kDa]Lane 2: Human cell line U-251 MG
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