APC2

Gene Symbol APC2
Entrez Gene 10297
Alt Symbol APCL
Species Human
Gene Type protein-coding
Description adenomatosis polyposis coli 2
Other Description adenomatous polyposis coli like|adenomatous polyposis coli protein 2
Swissprots Q9Y632 O95996 Q9UQJ9 Q9UQJ8 Q9UEM8 Q9UBZ1 Q05BW4
Accessions AAD29273 AAD29274 AAD29275 BAA75469 CAA10317 EAW69496 EAW69497 EAW69498 O95996 AB012162 BAA34611 AF110334 AAD28183 AF128222 AAF01784 AJ012652 CAB61207 AL078616 BC020381 BC032573 AAH32573 XM_005259475 XP_005259532 XM_006722607 XP_006722670 XM_006722608 XP_006722671 XM_006722609 XP_006722672 XM_006722610 XP_006722673 NM_005883 NP_005874
Function Promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. May function in Wnt signaling. {ECO:0000269|PubMed:10021369, ECO:0000269|PubMed:11691822, ECO:0000269|PubMed:9823329}.
Subcellular Location Cytoplasm, cytoskeleton. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with actin filaments and the microtubule network.
Tissue Specificity Widely expressed (at protein level). Specifically expressed in the CNS. {ECO:0000269|PubMed:10021369, ECO:0000269|PubMed:11691822, ECO:0000269|PubMed:9823329}.
Top Pathways Wnt signaling pathway, HTLV-I infection, Endometrial cancer, Colorectal cancer, Hippo signaling pathway

APC2 (A-17) - sc-9929 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

APC2 (L-17) - sc-12425 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
APC2 (L-17): sc-12425. Immunoperoxidase staining of formalin fixed, paraffin-embedded human vagina tissue showing cytoplasmic and membrane staining of squamous epithelial cells.

Anti-APC2 antibody - ab113370 from Abcam

Prices $407.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
ab113370, at 5 µg/ml, staining APC2 in Formalin-fixed, Paraffin-embedded Human Brain cortex tissue by Immunohistochemistry.

Anti-APC2 antibody - ab80018 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-APC2 antibody (ab80018) at 1 µg/ml + Spinal Cord (Human) Tissue Lysate - adult normal tissue (ab29188) at 10 µgSecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-APCL / APC2 Antibody (C-Terminus) IHC-plus™ - LS-B328 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-APC2 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B328 dilution 1:500.

Anti-APCL / APC2 Antibody (aa849-898) IHC-plus™ - LS-B5820 from LifeSpan Bioscience

Prices $450.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-APC2 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B5820 concentration 5 ug/ml.

Anti-APCL / APC2 Antibody (Internal) IHC-plus™ - LS-B4641 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-APC2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B4641 concentration 5 ug/ml.

Anti-APCL / APC2 Antibody (Azide-free) - LS-C88597 from LifeSpan Bioscience

Prices $650.00, $935.00
Sizes 500 µg, 1 mg
Host Rabbit
Clonality Polyclonal

Anti-APCL / APC2 Antibody - LS-C88596 from LifeSpan Bioscience

Prices $345.00, $590.00, $845.00
Sizes 100 µg, 500 µl, 1 mg
Host Rabbit
Clonality Polyclonal

Apc2 Antibody - NBP1-77376 from Novus Biologicals

Prices $329.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: Apc2 Antibody [NBP1-77376] - HeLa cell lysate with APC2 antibody at (A) 1 and (B) 2 ug/mL.

APCL/APC2 Polyclonal Antibody - bs-12485R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APCL/APC2 Polyclonal Antibody, ALEXA FLUOR® 350 Conjugated - bs-12485R-A350 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APCL/APC2 Polyclonal Antibody, ALEXA FLUOR® 488 Conjugated - bs-12485R-A488 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APCL/APC2 Polyclonal Antibody, ALEXA FLUOR® 555 Conjugated - bs-12485R-A555 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APCL/APC2 Polyclonal Antibody, ALEXA FLUOR® 647 Conjugated - bs-12485R-A647 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APCL/APC2 Polyclonal Antibody, Cy3 Conjugated - bs-12485R-Cy3 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APCL/APC2 Polyclonal Antibody, Cy5 Conjugated - bs-12485R-Cy5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APCL/APC2 Polyclonal Antibody, Cy5.5 Conjugated - bs-12485R-Cy5.5 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APCL/APC2 Polyclonal Antibody, Cy7 Conjugated - bs-12485R-Cy7 from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APCL/APC2 Polyclonal Antibody, FITC Conjugated - bs-12485R-FITC from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APCL/APC2 Polyclonal Antibody, Biotin Conjugated - bs-12485R-Biotin from Bioss

Prices $349.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

APCL/APC2 Polyclonal Antibody, HRP Conjugated - bs-12485R-HRP from Bioss

Prices $369.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-APC2 antibody produced in rabbit - AV50526 from Sigma-Aldrich

Prices $316.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-APC2: <B>Cat. No. AV50526</B>: Immunohistochemistry of APC2 in Skin tissue with APC2 antibody at 5.0 μg/mL.

Anti-APC2 antibody produced in rabbit - SAB2900319 from Sigma-Aldrich

Prices $464.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-APC2: <B>Cat. No.SAB2900319</B>: Skin: Formalin-Fixed Paraffin-Embedded (FFPE).

Anti-APC2 antibody produced in rabbit - SAB3500185 from Sigma-Aldrich

Prices $348.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-APC2: <B>Cat. No. SAB3500185</B>: Western blot analysis of APC2 in HeLa cell lysate with APC2 antibody at (A) 1 and (B) 2 μg/mL.
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