APC2

Gene Symbol APC2
Entrez Gene 10297
Alt Symbol APCL
Species Human
Gene Type protein-coding
Description adenomatosis polyposis coli 2
Other Description adenomatous polyposis coli like|adenomatous polyposis coli protein 2
Swissprots Q9Y632 O95996 Q9UQJ9 Q9UQJ8 Q9UEM8 Q9UBZ1 Q05BW4
Accessions AAD29273 AAD29274 AAD29275 BAA75469 CAA10317 EAW69496 EAW69497 EAW69498 O95996 AB012162 BAA34611 AF110334 AAD28183 AF128222 AAF01784 AJ012652 CAB61207 AL078616 BC020381 BC032573 AAH32573 XM_005259475 XP_005259532 XM_006722607 XP_006722670 XM_006722608 XP_006722671 XM_006722609 XP_006722672 XM_006722610 XP_006722673 NM_005883 NP_005874
Function Promotes rapid degradation of CTNNB1 and may function as a tumor suppressor. May function in Wnt signaling. {ECO:0000269|PubMed:10021369, ECO:0000269|PubMed:11691822, ECO:0000269|PubMed:9823329}.
Subcellular Location Cytoplasm, cytoskeleton. Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Note=Associated with actin filaments and the microtubule network.
Tissue Specificity Widely expressed (at protein level). Specifically expressed in the CNS. {ECO:0000269|PubMed:10021369, ECO:0000269|PubMed:11691822, ECO:0000269|PubMed:9823329}.
Top Pathways Wnt signaling pathway, HTLV-I infection, Endometrial cancer, Colorectal cancer, Hippo signaling pathway

APC2 CRISPR/Cas9 KO Plasmid (h) - sc-408180 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APC2 HDR Plasmid (h) - sc-408180-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APC2 Double Nickase Plasmid (h) - sc-408180-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APC2 Double Nickase Plasmid (h2) - sc-408180-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APC2 CRISPR Activation Plasmid (h) - sc-408180-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APC2 CRISPR Activation Plasmid (h2) - sc-408180-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

APC2 Lentiviral Activation Particles (h) - sc-408180-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APC2 Lentiviral Activation Particles (h2) - sc-408180-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

APC2 siRNA (h) - sc-37526 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

APC2 shRNA Plasmid (h) - sc-37526-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

APC2 shRNA (h) Lentiviral Particles - sc-37526-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

CompoZr® Knockout ZFN Kit - CKOZFN3311 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND3311 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

APC2 siRNA (Human) - CRH6977 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

APC2 - MBS828376 from MyBioSource

Prices $365.00, $515.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human APC2 (NM_005883.2) - SHH238118 from Creative biogene

Category siRNA
Species Reactivities Human

shRNA set against Human APC2(NM_005883.2) - SHG064081 from Creative biogene

Category siRNA
Species Reactivities Human

APC2 shRNA Plasmid (Human) - CHH6977 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

APC2 miRNA 3'UTR clone - MiUTR1H-00461 from Creative biogene

Species Reactivities Human
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