POMGNT2

Gene Symbol POMGNT2
Entrez Gene 84892
Alt Symbol AGO61, C3orf39, GTDC2, MDDGA8
Species Human
Gene Type protein-coding
Description protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
Other Description glycosyltransferase-like domain containing 2|glycosyltransferase-like domain-containing protein 2|protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2
Swissprots Q8NAT1 Q96SY3 B3KWC3
Accessions CAC33413 EAW64690 EAW64691 EAW64692 Q8NAT1 AK027472 BAB55137 AK092147 BAC03816 AK124737 BAG54085 BC004508 BC021220 BC060861 AAH60861 JF432408 ADZ15625 XM_005265515 XP_005265572 XM_011534163 XP_011532465 XM_011534164 XP_011532466 NM_032806 NP_116195
Function O-linked mannose beta-1,4-N- acetylglucosaminyltransferase that tranfers UDP-N-acetyl-D- glucosamine to the 4-position of the mannose to generate N-acetyl- D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N- acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate- 6-)mannose), a carbohydrate structure present in alpha- dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. {ECO:0000269|PubMed:23929950}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:23929950}; Single-pass type II membrane protein {ECO:0000269|PubMed:23929950}.
Tissue Specificity Highly expressed in the brain, muscle, heart, and kidney in both fetus and adult. In the brain, highest expression in the cortex and cerebellum. Highly expressed in the pancreas. {ECO:0000269|PubMed:22958903}.

C3orf39 CRISPR/Cas9 KO Plasmid (h) - sc-410214 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C3orf39 HDR Plasmid (h) - sc-410214-HDR from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C3orf39 Double Nickase Plasmid (h) - sc-410214-NIC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C3orf39 Double Nickase Plasmid (h2) - sc-410214-NIC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C3orf39 CRISPR Activation Plasmid (h) - sc-410214-ACT from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C3orf39 CRISPR Activation Plasmid (h2) - sc-410214-ACT-2 from Santa Cruz Biotechnology

Category CRISPR
Prices $345.00
Sizes 20 µg
Species Reactivities Human

C3orf39 Lentiviral Activation Particles (h) - sc-410214-LAC from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C3orf39 Lentiviral Activation Particles (h2) - sc-410214-LAC-2 from Santa Cruz Biotechnology

Prices $345.00
Sizes 20 µg
Species Reactivities Human

C3orf39 siRNA (h) - sc-78425 from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C3orf39 shRNA Plasmid (h) - sc-78425-SH from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

C3orf39 shRNA (h) Lentiviral Particles - sc-78425-V from Santa Cruz Biotechnology

Category siRNA
Prices $258.00
Sizes 10 µm
Species Reactivities Human

MISSION® esiRNA - EHU154921 from Sigma-Aldrich

Category siRNA
Prices $140.00, $250.00
Sizes 20 µg, 50 µg

CompoZr® Knockout ZFN Kit - CKOZFN4898 from Sigma-Aldrich

Category ZFN Kit
Prices $4,999.00
Sizes 1 kt

CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND4898 from Sigma-Aldrich

Category ZFN Kit
Prices $3,999.00
Sizes 1 kt

MISSION® 3′UTR Lenti GoClone™ - HUTR03871 from Sigma-Aldrich

Category miRNA
Prices $350.00
Sizes hutr03871

POMGNT2 siRNA (Human) - CRJ3670 from Cohesion Biosciences

Category siRNA
Prices $340.00, $510.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

shRNA set against Human C3orf39 (NM_032806.5) - SHH251673 from Creative biogene

Category siRNA
Species Reactivities Human

Human POMGNT2 siRNA - orb274171 from Biorbyt

Category siRNA
Prices $485.00, $629.00
Sizes 15 nmol, 30 nmol
Species Reactivities Human

POMGNT2 shRNA Plasmid (Human) - CHJ3670 from Cohesion Biosciences

Category siRNA
Prices $500.00, $750.00
Sizes 150 µg, 300 µg
Species Reactivities Human

GTDC2 miRNA 3'UTR clone - MiUTR3H-13420 from Creative biogene

Species Reactivities Human
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