POMGNT2

Gene Symbol POMGNT2
Entrez Gene 84892
Alt Symbol AGO61, C3orf39, GTDC2, MDDGA8
Species Human
Gene Type protein-coding
Description protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-)
Other Description glycosyltransferase-like domain containing 2|glycosyltransferase-like domain-containing protein 2|protein O-linked-mannose beta-1,4-N-acetylglucosaminyltransferase 2
Swissprots Q8NAT1 Q96SY3 B3KWC3
Accessions CAC33413 EAW64690 EAW64691 EAW64692 Q8NAT1 AK027472 BAB55137 AK092147 BAC03816 AK124737 BAG54085 BC004508 BC021220 BC060861 AAH60861 JF432408 ADZ15625 XM_005265515 XP_005265572 XM_011534163 XP_011532465 XM_011534164 XP_011532466 NM_032806 NP_116195
Function O-linked mannose beta-1,4-N- acetylglucosaminyltransferase that tranfers UDP-N-acetyl-D- glucosamine to the 4-position of the mannose to generate N-acetyl- D-glucosamine-beta-1,4-O-D-mannosylprotein. Involved in the biosynthesis of the phosphorylated O-mannosyl trisaccharide (N- acetylgalactosamine-beta-3-N-acetylglucosamine-beta-4-(phosphate- 6-)mannose), a carbohydrate structure present in alpha- dystroglycan (DAG1), which is required for binding laminin G-like domain-containing extracellular proteins with high affinity. {ECO:0000269|PubMed:23929950}.
Subcellular Location Endoplasmic reticulum membrane {ECO:0000269|PubMed:23929950}; Single-pass type II membrane protein {ECO:0000269|PubMed:23929950}.
Tissue Specificity Highly expressed in the brain, muscle, heart, and kidney in both fetus and adult. In the brain, highest expression in the cortex and cerebellum. Highly expressed in the pancreas. {ECO:0000269|PubMed:22958903}.

C3orf39 (C-16) - sc-99801 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal

C3orf39 (N-17) - sc-99803 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
C3orf39 (N-17): sc-99803. Immunofluorescence staining of formalin-fixed HepG2 cells showing membrane localization.

C3orf39 (T-25) - sc-130998 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
C3orf39 (T-25): sc-130998. Western blot analysis of C3orf39 expression in Hep G2 whole cell lysate.

Anti-C3orf39 antibody - ab89975 from Abcam

Prices $370.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Anti-C3orf39 antibody (ab89975) at 1 µg/ml + SH-SYSY cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-POMGNT2 / GTDC2 Antibody (aa351-400) - LS-C81337 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HepG2 cell lysate. Antibody concentration: 1.25 ug/ml. Gel concentration: 12%.

Anti-POMGNT2 / GTDC2 Antibody - LS-C308142 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-POMGNT2 / GTDC2 Antibody - LS-C335679 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunofluorescence analysis of A549 cell using GTDC2 antibody. Blue: DAPI for nuclear staining.

Anti-POMGNT2 / GTDC2 Antibody (N-Terminus) - LS-C111209 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
C3orf39 antibody LS-C111209 Western blot of SH-SYSY lysate.

C3orf39 Antibody - NBP1-89205 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: C3orf39 Antibody [NBP1-89205] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

C3orf39 Antibody - NBP1-79304 from Novus Biologicals

Prices $139.00, $329.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: C3orf39 Antibody [NBP1-79304] - Titration: 0.2-1 ug/ml, Positive Control: SH-SYSY cell lysate.

C3orf39 Antibody - NBP1-79305 from Novus Biologicals

Prices $139.00, $299.00
Sizes 20 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: C3orf39 Antibody [NBP1-79305] - HepG2 cell lysate, concentration 1.25ug/ml.

C3orf39 Antibody - NBP2-34067 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: C3orf39 Antibody [NBP2-34067] - Staining of human kidney shows strong cytoplasmic positivity in cells in tubules.

C3orf39 Antibody - H00084892-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

C3orf39 Antibody - H00084892-B01 from Novus Biologicals

Prices $349.00
Sizes 50 µl
Host Mouse
Clonality Polyclonal
Western Blot: C3orf39 Antibody [H00084892-B01] - analysis of C3orf39 expression in transfected 293T cell line by C3orf39 MaxPab polyclonal antibody (B01). Lane 1: C3orf39 transfected lysate (66.60 KDa). Lane 2: Non-transfected lysate.

C3orf39 Polyclonal Antibody - bs-9830R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-C3ORF39 antibody produced in rabbit - AV48972 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Cell Type: HepG2 (<B>Cat. No. AV48972</B>).<BR/><B>Lanes</B><BR/>1. Antibody dilution (concentration) 1.25 μg/mL in cell type HepG2

Anti-C3ORF39, (N-terminal) antibody produced in rabbit - SAB2103728 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-C3ORF39, antibody produced in rabbit: <B>Cat. No. SAB2103728</B>: Immunoblotting analysis of C3orf39 in SH-SYSY cell lysate with C3orf39 anitbody at 1 μg/mL.

Anti-C3orf39 antibody produced in mouse - SAB1401912 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-C3orf39, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1401912</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~63.8 kDa using C3orf39 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-C3orf39 (401-415) antibody produced in rabbit - SAB1105819 from Sigma-Aldrich

Prices $279.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Lysate of HEK-293T cells overexpressing human C3orf39 was separated on SDS-PAGE, blotted with Anti-C3orf39 (401-415) (<B>Cat. No. SAB1105819</B>) and developed using Goat Anti-Rabbit IgG-Peroxidase (<B>Cat. No. A0545</B>) and a chemiluminescent substrate.<BR/><B>Lanes</B><BR/>1. Antibody dilution 1:250

Anti-GTDC2 antibody produced in rabbit - HPA034870 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-C3ORF39: <B>Cat. No. HPA034870</B>: Immunohistochemical staining of human prostate shows strong cytoplasmic positivity in glandular cells.

Anti-GTDC2 antibody produced in rabbit - HPA040989 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-GTDC2: <B>Cat. No. HPA040989</B>: Immunohistochemical staining of Human kidney shows strong cytoplasmic positivity in cells in tubules.

C3orf39 antibody - N-terminal region (ARP48971_P050) - ARP48971_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C3orf39 antibody - middle region (ARP48972_T100) - ARP48972_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

C3ORF39 antibody, Internal - GTX46151 from GeneTex

Prices $319.00
Sizes 100 μg
Host Rabbit
Clonality Polyclonal
Anti-C3ORF39 antibody, Internal used in Western blot. GTX46151

C3ORF39 antibody, N-term - GTX46152 from GeneTex

Prices $319.00
Sizes 50 μg
Host Rabbit
Clonality Polyclonal
Anti-C3ORF39 antibody, N-term used in Western blot. GTX46152
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