Gene Symbol | SSC5D |
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Entrez Gene | 284297 |
Alt Symbol | - |
Species | Human |
Gene Type | protein-coding |
Description | scavenger receptor cysteine rich family, 5 domains |
Other Description | scavenger receptor cysteine rich domain containing (5 domains)|scavenger receptor cysteine-rich glycoprotein|soluble scavenger protein with 5 SRCR domains|soluble scavenger receptor cysteine-rich domain-containing protein SSC5D|soluble scavenger with 5 domains |
Swissprots | K7EP70 B5MDQ5 C7S7U0 A1L4H1 C7S7T9 |
Accessions | A1L4H1 AF086519 AK092577 BAC03917 BC130538 AAI30539 BC130540 AAI30541 DA008417 EU699476 ACJ02751 EU699477 ACJ02752 XM_011526758 XP_011525060 XM_011526759 XP_011525061 NM_182571 NM_001144950 NP_001138422 NM_001195267 NP_001182196 |
Function | Binds to extracellular matrix proteins. Binds to pathogen-associated molecular patterns (PAMPs) present on the cell walls of Gram-positive and Gram-negative bacteria and fungi, behaving as a pattern recognition receptor (PRR). Induces bacterial and fungal aggregation and subsequent inhibition of PAMP-induced cytokine release. Does not possess intrinsic bactericidal activity. May play a role in the innate defense and homeostasis of certain epithelial surfaces (By similarity). {ECO:0000250}. |
Subcellular Location | Secreted {ECO:0000250}. Cytoplasm {ECO:0000250}. |
Tissue Specificity | Highly expressed in monocytes/macrophages and T-lymphocytes. Highly expressed in placenta and spleen, and also detected at lower levels in colon, and more weakly in lung, heart and kidney. {ECO:0000269|PubMed:19535143}. |
Anti-SSC5D antibody - ab129653 from Abcam
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Anti-SSC5D antibody - ab122768 from Abcam
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Anti-SSC5D Antibody (aa868-897, AP) - LS-C270412 from LifeSpan Bioscience
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Anti-SSC5D Antibody (aa868-897, Biotin) - LS-C270414 from LifeSpan Bioscience
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Anti-SSC5D Antibody (aa868-897, APC) - LS-C270413 from LifeSpan Bioscience
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Anti-SSC5D Antibody (aa868-897, Azide-free, HRP) - LS-C270416 from LifeSpan Bioscience
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Anti-SSC5D Antibody (aa868-897, FITC) - LS-C270415 from LifeSpan Bioscience
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Anti-SSC5D Antibody (aa868-897, PE) - LS-C270417 from LifeSpan Bioscience
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Anti-SSC5D Antibody (aa868-897) - LS-C325395 from LifeSpan Bioscience
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Anti-SSC5D Antibody (aa868-897) - LS-C161515 from LifeSpan Bioscience
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SSC5D Antibody - NBP1-93831 from Novus Biologicals
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ANTI-SSC5D (CENTER) antibody produced in rabbit - SAB1304024 from Sigma-Aldrich
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SSC5D-Antibody-Center - AP16565c from Abgent, a WuXi AppTec company
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SSC5D Antibody - middle region (OAAB11983) - OAAB11983 from Aviva Systems Biology
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SSC5D Antibody - abx028908 from Abbexa
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SSC5D (Center) antibody - AP54049PU-N from Acris Antibodies
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SSC5D antibody (Center) - STJ45057 from St John's Laboratory Ltd
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Anti-SSC5D (aa 870-962) polyclonal antibody - DPABH-21062 from Creative Diagnostics
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Anti-SSC5D (aa 868-897) polyclonal antibody - DPABH-24022 from Creative Diagnostics
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SSC5D, Polyclonal Antibody - MBS6012007 from MyBioSource
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SSC5D, Polyclonal Antibody - MBS9214342 from MyBioSource
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Anti-SSC5D antibody produced in rabbit - HPA042008 from Sigma-Aldrich
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SSC5D Antibody - 58-574 from ProSci
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SSC5D antibody - orb164171 from Biorbyt
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