| Gene Symbol |
PLA2G4F
|
| Entrez Gene |
255189
|
| Alt Symbol |
PLA2G4FZ
|
| Species |
Human
|
| Gene Type |
protein-coding
|
| Description |
phospholipase A2, group IVF
|
| Other Description |
cPLA2-zeta|cytosolic phospholipase A2 zeta
|
| Swissprots |
Q68DD2 Q6ZMC8
|
| Accessions |
EAW92531 EAW92532 EAW92533 EAW92534 Q68DD2 AK122623 BAG53627 AK172836 BAD18801 AK304368 BAG65207 AL832972 BC035335 AAH35335 BC040920 BC111481 BC131531 AAI31532 BC142682 AAI42683 BC146648 AAI46649 BM986790 CR749451 CAH18288 XR_931785 XR_931786 NM_213600 NP_998765 NR_033151
|
| Function |
Calcium-dependent phospholipase A2 that selectively hydrolyzes glycerophospholipids in the sn-2 position. Has higher enzyme activity for phosphatidylethanolamine than phosphatidylcholine (By similarity). {ECO:0000250}.
|
| Subcellular Location |
Cytoplasm, cytosol. Lysosome membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}; Cytoplasmic side {ECO:0000250}. Note=Translocates to lysosomal membranes in a calcium-dependent fashion. {ECO:0000250}.
|
| Top Pathways |
Glutamatergic synapse, Choline metabolism in cancer, Oxytocin signaling pathway, VEGF signaling pathway, Inflammatory mediator regulation of TRP channels
|