PSRC1

Gene Symbol PSRC1
Entrez Gene 84722
Alt Symbol DDA3, FP3214
Species Human
Gene Type protein-coding
Description proline/serine-rich coiled-coil 1
Other Description differential display and activated by p53|p53-regulated DDA3|proline/serine-rich coiled-coil protein 1
Swissprots Q9BV77 Q5T2Z3 Q6ZTI8 Q71MG3 Q6PGN9
Accessions AAN73434 EAW56373 EAW56374 EAW56375 EAW56376 EAW56377 Q6PGN9 AF223000 AAN73431 AF447874 AAQ04649 AK126567 BAC86599 AK289593 BAF82282 BC056909 AAH56909 BE206101 BF984061 BI857497 BJ992594 BQ448200 BX649139 HQ448122 ADQ32603 XM_005271283 XP_005271340 XM_006710982 XP_006711045 XM_011542306 XP_011540608 NM_001005290 NP_001005290 NM_001032291 NP_001027462 NM_001032290 NM_032636 NP_116025
Function Required for normal progression through mitosis. Required for normal congress of chromosomes at the metaphase plate, and for normal rate of chromosomal segregation during anaphase. Plays a role in the regulation of mitotic spindle dynamics. Increases the rate of turnover of microtubules on metaphase spindles, and contributes to the generation of normal tension across sister kinetochores. Recruits KIF2A to the mitotic spindle and spindle poles. May participate in p53/TP53-regulated growth suppression. {ECO:0000269|PubMed:18411309, ECO:0000269|PubMed:19738423}.
Subcellular Location Cytoplasm. Cytoplasm, cytoskeleton, spindle. Cytoplasm, cytoskeleton, spindle pole. Note=Detected at the mitotic spindle and spindle poles. Diffusely distributed throughout the cell during interphase.
Tissue Specificity Widely expressed in adult and fetal tissues, with highest expression in the adult brain and fetal thymus. Not detected in adult skeletal muscle. {ECO:0000269|PubMed:12427559}.

DDA3 (K-14) - sc-160272 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
DDA3 (K-14): sc-160272. Western blot analysis of DDA3 expression in non-transfected 293T: sc-117752 (A), human DDA3 transfected 293T: sc-116630 (B) and MCF7 (C) whole cell lysates.

Anti-PSRC1 antibody - ab187199 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PSRC1 antibody (ab187199) at 1/500 dilutionLane 1 : MCF-7 cell extractLane 2 : HepG2 cell extractLane 3 : 293T cell extract

Anti-PSRC1 antibody - ab169124 from Abcam

Prices $370.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
All lanes : Anti-PSRC1 antibody (ab169124) at 1 µg/mlLane 1 : PSRC1 transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.developed using the ECL technique

Anti-PSRC1 antibody - ab172900 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-PSRC1 antibody (ab172900) at 1 µg/mlLane 1 : PSRC1-transfected 293T cell lysateLane 2 : Non-transfected 293T cell lysateLysates/proteins at 15 µl per lane.SecondaryGoat Anti-Rabbit IgG (H+L), Peroxidase Conjugated at 1/7500 dilutiondeveloped using the ECL technique

Anti-PSRC1 / DDA3 Antibody (aa343-371, APC) - LS-C267348 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PSRC1 / DDA3 Antibody (aa343-371, AP) - LS-C267346 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PSRC1 / DDA3 Antibody (aa343-371, FITC) - LS-C267352 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PSRC1 / DDA3 Antibody (aa343-371) - LS-C330032 from LifeSpan Bioscience

Prices $435.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PSRC1 / DDA3 Antibody (aa343-371, PE) - LS-C267353 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PSRC1 / DDA3 Antibody (aa343-371, Azide-free, HRP) - LS-C267351 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PSRC1 / DDA3 Antibody (aa343-371, Biotin) - LS-C267350 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PSRC1 / DDA3 Antibody - LS-C341632 from LifeSpan Bioscience

Prices $385.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal

Anti-PSRC1 / DDA3 Antibody - LS-C334083 from LifeSpan Bioscience

Prices $255.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using PSRC1 antibody.

PSRC1 Antibody - NBP2-13823 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry-Paraffin: PSRC1 Antibody [NBP2-13823] Staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.

PSRC1 Antibody - H00084722-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

PSRC1 Antibody - H00084722-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: PSRC1 Antibody [H00084722-D01P] - Analysis of PSRC1 expression in transfected 293T cell line by PSRC1 polyclonal antibody.Lane 1: PSRC1 transfected lysate(35.60 KDa).Lane 2: Non-transfected lysate.

PSRC1 Polyclonal Antibody - bs-7619R from Bioss

Prices $269.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-PSRC1 antibody produced in rabbit - SAB1411520 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PSRC1: <B>Cat. No. SAB1411520</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~35.6 kDa using PSRC1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PSRC1 antibody produced in rabbit - HPA049315 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-PSRC1:<B>Cat. No. HPA049315</B>: Immunohistochemical staining of human cerebellum shows strong cytoplasmic positivity in Purkinje cells.

Anti-PSRC1 antibody produced in mouse - SAB1408123 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-PSRC1: <B>Cat. No. SAB1408123</B>: Antibody concentration: 0.1-5 μg/mL. Specific band of ~40 kDa using PSRC1 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

PSRC1 Antibody - C-terminal region (ARP75826_P050) - ARP75826_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

PSRC1 Antibody - C-terminal region (OAAB00183) - OAAB00183 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal

PSRC1 Polyclonal Antibody - A5484 from ABclonal

Prices $130.00, $220.00, $380.00
Sizes 50 µl, 100 µl, 200 µl
Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts of various cell lines, using PSRC1 antibody.

PSRC1 Antibody - abx004201 from Abbexa

Host Rabbit
Clonality Polyclonal

PSRC1 / DDA3 antibody - H00084722-B01P from Acris Antibodies

Prices $360.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot analysis of PSRC1 expression in transfected 293T cell line (H00084722-T01) by PSRC1 MaxPab polyclonal antibody. Lane 1: PSRC1 transfected lysate(40.04 KDa). Lane 2: Non-transfected lysate.
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