NBR1

Gene Symbol NBR1
Entrez Gene 4077
Alt Symbol 1A1-3B, IAI3B, M17S2, MIG19
Species Human
Gene Type protein-coding
Description neighbor of BRCA1 gene 1
Other Description B-box protein|cell migration-inducing gene 19 protein|membrane component, chromosome 17, surface marker 2 (ovarian carcinoma antigen CA125)|migration-inducing protein 19|next to BRCA1 gene 1 protein
Swissprots Q15026 Q13173 Q14596 Q5J7Q8 Q9NRF7 Q96GB6
Accessions AAA93228 ABA29210 ABA29213 ABA29216 ABA29219 ABA29222 ABA29225 ABA29228 ABA29231 ABF14461 EAW60946 EAW60947 EAW60948 EAW60949 EAW60950 EAW60951 EAW60952 EAW60953 Q14596 AF227189 AAF74119 AK128512 AK290005 BAF82694 AK297425 BAH12580 AK299328 BAH13002 AK308324 AW874218 AY450308 AAS15047 BC009808 AAH09808 BC012591 BC012847 BM509256 CD673012 D30756 BAA06417 DB081342 HY045337 X76952 CAA54274 XM_006721903 XP_006721966 XM_011524813 XP_011523115 NM_001291571 NP_001278500 NM_001291572 NP_001278501 NM_005899 NP_005890 NM_031862 NP_114068 NM_031858
Function Acts probably as a receptor for selective autophagosomal degradation of ubiquitinated targets. {ECO:0000269|PubMed:19250911}.
Subcellular Location Cytoplasm. Cytoplasmic vesicle, autophagosome. Lysosome. Cytoplasm, myofibril, sarcomere, M line {ECO:0000250}. Note=In cardiac muscles localizes to the sarcomeric M line (By similarity). Is targeted to lysosomes for degradation. {ECO:0000250}.

NBR1 (D2E6) Rabbit mAb - 9891 from Cell Signaling Technology

Prices $246.00
Sizes 100 µl (10 western blots)
Host Rabbit
Clonality Monoclonal
Clone D2E6
Western blot analysis of extracts from various cell lines using NBR1 (D2E6) Rabbit mAb.

NBR1 Antibody - 5202 from Cell Signaling Technology

Host Rabbit
Clonality Polyclonal
Western blot analysis of extracts from HeLa and Hep G2 cells using NBR1 Antibody.

NBR1 (4BR) - sc-130380 from Santa Cruz Biotechnology

Prices $295.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal
NBR1 (4BR): sc-130380. Western blot analysis of NBR1 expression in PC-12 whole cell lysate.

Anti-NBR1 antibody - ab55474 from Abcam

Prices $390.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Overlay histogram showing HeLa cells stained with ab55474 (red line). The cells were fixed with 80% methanol (5 min) and then permeabilized with 0.1% PBS-Tween for 20 min. The cells were then incubated in 1x PBS / 10% normal goat serum / 0.3M glycine to block non-specific protein-protein interactions followed by the antibody (ab55474, 1μg/1x106 cells) for 30 min at 22°C. The secondary antibody used was DyLight® 488 goat anti-mouse IgG (H+L) (ab96879) at 1/500 dilution for 30 min at 22°C. Isotype control antibody (black line) was mouse IgG2a [ICIGG2A] (ab91361, 1μg/1x106 cells) used under the same conditions. Unlabelled sample (blue line) was also used as a control. Acquisition of >5,000 events were collected using a 20mW Argon ion laser (488nm) and 525/30 bandpass filter. This antibody gave a positive signal in HeLa cells fixed with 4% paraformaldehyde (10 min)/permeabilized with 0.1% PBS-Tween for 20 min used under the same conditions.

Anti-NBR1 antibody - ab126175 from Abcam

Prices $376.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-NBR1 antibody (ab126175) at 1/1000 dilution + Jurkat whole cell lysate at 30 µg

Anti-NBR1 Antibody (DY650) - LS-C180661 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NBR1 Antibody (Biotin) - LS-C180660 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NBR1 Antibody (DY488) - LS-C180662 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NBR1 Antibody (DY550) - LS-C180663 from LifeSpan Bioscience

Prices $365.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-NBR1 Antibody (aa2-97, Azide-free) - LS-C330552 from LifeSpan Bioscience

Host Mouse
Clonality Monoclonal

Anti-NBR1 Antibody (aa776-825) - LS-C135299 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
NBR1 antibody LS-C135299 Western blot of Mouse Spleen lysate.

Anti-NBR1 Antibody (clone 6B11) - LS-C197634 from LifeSpan Bioscience

Prices $355.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6B11
Detection limit for recombinant GST tagged NBR1 is approximately 0.1 ng/ml as a capture antibody.

Anti-NBR1 Antibody - LS-C343777 from LifeSpan Bioscience

Prices $415.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western blot of Nrb1 in HeLa S100 lysate (25 ug) using BML-PW1125 at 1:1000 dilution.

Anti-NBR1 Antibody - LS-C180110 from LifeSpan Bioscience

Prices $335.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunohistochemistry: NBR1 Antibody - Staining of NBRI in mouse prostate.

Anti-NBR1 Antibody - LS-C332925 from LifeSpan Bioscience

Prices $305.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
Immunohistochemistry analysis of paraffin-embedded human liver, using NBR1 antibody.

NBR1 Antibody - NBP1-71703 from Novus Biologicals

Prices $99.00, $299.00
Sizes 25 µl, 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NBR1 Antibody [NBP1-71703] - WB analysis of 30 ug whole cell lysate of HeLa cells using NBR1 antibody.

NBR1 Antibody (6B11) - H00004077-M01 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 6B11
Western Blot: NBR1 Antibody (6B11) [H00004077-M01] - Western Blot analysis of NBR1 expression in PC-12

NBR1 Antibody - H00004077-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

NBR1 Antibody - NBP2-19481 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: NBR1 Antibody [NBP2-19481] - Sample (30 ug of whole cell lysate) A: NIH-3T3 B: JC 7. 5% SDS PAGE gel, diluted at 1:1000.

NBR1 Antibody - NBP1-89399 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

NBR1 Antibody (5C3) - H00004077-M05 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 5C3
Western Blot: NBR1 Antibody (5C3) [H00004077-M05] - Western blot analysis of NBR1 over-expressed 293 cell line, cotransfected with NBR1 Validated Chimera RNAi or non-transfected control. Blot probed with H00004077-M05. GAPDH (36.1 kDa) used as loading control.

NBR1 Antibody (5C3) - H00004077-M05A from Novus Biologicals

Prices $359.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 5C3
Western Blot: NBR1 Antibody (5C3) [H00004077-M05A] - Analysis of NBR1 expression in transfected 293T cell line by NBR1 monoclonal antibody (M05A), clone 5C3. Lane 1: NBR1 transfected lysatE (107.4 KDa). Lane 2: Non-transfected lysate.

NBR1 Antibody (3D3) - H00004077-M03 from Novus Biologicals

Prices $349.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 3D3
ELISA: NBR1 Antibody (3D3) [H00004077-M03] - Detection limit for recombinant GST tagged NBR1 is approximately 0.1ng/ml as a capture antibody.

NBR1 Antibody (2E7.) - H00004077-M02 from Novus Biologicals

Prices $359.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 2E7.
Sandwich ELISA: NBR1 Antibody (2E7) [H00004077-M02] - Detection limit for recombinant GST tagged NBR1 is approximately 0.03ng/ml as a capture antibody.

NBR1 Antibody (3D3) - H00004077-M03A from Novus Biologicals

Prices $349.00
Sizes 200 µl
Host Mouse
Clonality Monoclonal
Clone 3D3
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