Gene Symbol | POLR2I |
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Entrez Gene | 5438 |
Alt Symbol | RPB9, hRPB14.5 |
Species | Human |
Gene Type | protein-coding |
Description | polymerase (RNA) II (DNA directed) polypeptide I, 14.5kDa |
Other Description | DNA-directed RNA polymerase II 14.5 kDa polypeptide|DNA-directed RNA polymerase II subunit I|DNA-directed RNA polymerase II subunit RPB9|RNA polymerase II 14.5 kDa subunit|RNA polymerase II subunit B9|RPB14.5 |
Swissprots | B2R5J2 Q6NW05 P36954 |
Accessions | AAB51181 CAA80649 P36954 AK312206 BAG35139 BC017112 AAH17112 BC017860 BC067794 AAH67794 DQ893214 ABM84140 DQ896543 ABM87542 NM_006233 NP_006224 |
Function | DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Component of RNA polymerase II which synthesizes mRNA precursors and many functional non-coding RNAs. Pol II is the central component of the basal RNA polymerase II transcription machinery. It is composed of mobile elements that move relative to each other. RPB9 is part of the upper jaw surrounding the central large cleft and thought to grab the incoming DNA template (By similarity). {ECO:0000250}. |
Subcellular Location | Nucleus {ECO:0000269|PubMed:9852112}. |
Top Pathways | Huntington's disease, Epstein-Barr virus infection, Purine metabolism, RNA polymerase, Pyrimidine metabolism |
Human RNA Polymerase II p14.5 full length protein - ab81852 from Abcam
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Human RNA Polymerase II p14.5 full length protein - ab81884 from Abcam
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POLR2I Antibody Blocking Peptide - LS-E13954 from LifeSpan Bioscience
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POLR2I Antibody Blocking Peptide - LS-E12724 from LifeSpan Bioscience
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RPB9 Partial Recombinant Protein - H00005438-Q01 from Novus Biologicals
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RPB9 Recombinant Protein - H00005438-P01 from Novus Biologicals
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Recombinant Human RPB9 Protein - NBP2-23346 from Novus Biologicals
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POLR2I-Antibody-N-term-Blocking-Peptide - BP14668a from Abgent, a WuXi AppTec company
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Human POLR2I protein - orb191401 from Biorbyt
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POLR2I protein (His tag) - 80R-2606 from Fitzgerald
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POLR2I Blocking Peptide - abx063105 from Abbexa
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POLR2I (1-125, His-tag) - AR50652PU-N from Acris Antibodies
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POLR2I (1-125, His-tag) - AR50652PU-S from Acris Antibodies
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POLR2I - H00005438-P01-10 from Acris Antibodies
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POLR2I - H00005438-P01-25 from Acris Antibodies
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POLR2I - H00005438-Q01-10 from Acris Antibodies
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POLR2I - H00005438-Q01-25 from Acris Antibodies
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POLR2I, 1-125aa, Human, His tag, E.coli - 01-P1828 from ARP American Research Products
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POLR2I fusion protein - Ag11027 from Proteintech Group
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POLR2I fusion protein - Ag11219 from Proteintech Group
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Recombinant Human POLR2I, His-tagged - POLR2I-522H from Creative Biomart
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Recombinant Human POLR2I, His-tagged - POLR2I-30764TH from Creative Biomart
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Recombinant Human POLR2I - POLR2I-30766TH from Creative Biomart
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Recombinant Human POLR2I, His-tagged - POLR2I-8463H from Creative Biomart
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Recombinant Human POLR2I, GST-tagged - POLR2I-1847H from Creative Biomart
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