HNRNPDL

Gene Symbol HNRNPDL
Entrez Gene 9987
Alt Symbol HNRNP, HNRPDL, JKTBP, JKTBP2, LGMD1G, laAUF1
Species Human
Gene Type protein-coding
Description heterogeneous nuclear ribonucleoprotein D-like
Other Description A+U-rich element RNA binding factor|AU-rich element RNA-binding factor|JKT41-binding protein|hnRNP D-like|hnRNP DL|protein laAUF1
Swissprots O14979 Q96S43 Q7KZ74 Q7KZ75 Q6SPF2 Q96IM0
Accessions AAY40914 BAA75239 BAA75240 CBF67589 CBU92463 EAX05885 EAX05886 EAX05887 EAX05888 EAX05889 EAX05890 EAX05891 O14979 AB017019 BAA75241 AB066484 BAB62188 AK057480 AK294683 BAG57844 AK300122 BAG61914 AY453824 AAR17782 BC007392 AAH07392 BC011714 AAH11714 BC018961 BC071944 AAH71944 CK300994 CR407623 CAG28551 D89092 BAA24361 D89678 BAA22860 DQ892871 ABM83797 DQ896119 ABM87118 X75683 NM_001207000 NP_001193929 NM_031372 NP_112740 NR_003249 NM_005463
Function Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity). Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence. {ECO:0000250, ECO:0000269|PubMed:9538234}.
Subcellular Location Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm in a TNPO1-dependent manner.
Tissue Specificity Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. Expressed in myeloid leukemia, gastric adenocarcinoma, cervical carcinoma, hepatoma, fibrosarcoma, colon adenocarcinoma, epidermoid carcinoma, osteosarcoma and urinary bladder carcinoma cells. {ECO:0000269|PubMed:10072754, ECO:0000269|PubMed:9538234}.

Human HNRPDL protein fragment - ab160746 from Abcam

Category Protein
Source Wheat germ
Species Human
ab160746 on a 12.5% SDS-PAGE stained with Coomassie Blue.

HNRNPDL / hnRNP D Antibody Blocking Peptide - LS-E14835 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

HNRNPDL / hnRNP D Antibody Blocking Peptide - LS-E7831 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human HNRPDL Protein - H00009987-Q01 from Novus Biologicals

Category Protein
Prices $369.00, $529.00
Sizes 10 µg, 25 µg
Source Wheat Germ
Species Human

HNRPDL-Antibody-Center-Blocking-peptide - BP5352c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

HNRPDL Blocking Peptide - 33R-9199 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

HNRPDL Blocking Peptide - 33R-10241 from Fitzgerald

Category Peptide
Prices $130.00
Sizes 100 µg

hnRPD-like protein / HNRPDL - H00009987-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Species Human

hnRPD-like protein / HNRPDL - H00009987-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Species Human

HNRPDL fusion protein - Ag1046 from Proteintech Group

Category Protein
Prices $199.00
Sizes 50 μg
Source E. coli -derived, PGEX-4T
Species Human

Recombinant Human HNRPDL, GST-tagged - HNRPDL-13878H from Creative Biomart

Category Protein
Source E.coli
Species Human

Recombinant Human Heterogeneous nuclear ribonucleoprotein D-like(HNRPDL) - CSB-YP010628HU CSB-EP010628HU CSB-BP010628HU CSB-MP010628HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

HNRPDL Recombinant Protein Antigen - NBP2-38806PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

HNRPDL Recombinant Protein Antigen - NBP2-38017PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

HNRPDL Peptide, Human - M34GP07169H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Heterogeneous nuclear ribonucleoprotein D-like (HNRPDL), Recombinant Protein - MBS1122181 from MyBioSource

Category Protein
Prices $1,195.00, $1,195.00, $1,415.00, $1,415.00, $1,925.00, $1,925.00, $2,390.00, $2,390.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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