HNRNPDL

Gene Symbol HNRNPDL
Entrez Gene 9987
Alt Symbol HNRNP, HNRPDL, JKTBP, JKTBP2, LGMD1G, laAUF1
Species Human
Gene Type protein-coding
Description heterogeneous nuclear ribonucleoprotein D-like
Other Description A+U-rich element RNA binding factor|AU-rich element RNA-binding factor|JKT41-binding protein|hnRNP D-like|hnRNP DL|protein laAUF1
Swissprots O14979 Q96S43 Q7KZ74 Q7KZ75 Q6SPF2 Q96IM0
Accessions AAY40914 BAA75239 BAA75240 CBF67589 CBU92463 EAX05885 EAX05886 EAX05887 EAX05888 EAX05889 EAX05890 EAX05891 O14979 AB017019 BAA75241 AB066484 BAB62188 AK057480 AK294683 BAG57844 AK300122 BAG61914 AY453824 AAR17782 BC007392 AAH07392 BC011714 AAH11714 BC018961 BC071944 AAH71944 CK300994 CR407623 CAG28551 D89092 BAA24361 D89678 BAA22860 DQ892871 ABM83797 DQ896119 ABM87118 X75683 NM_001207000 NP_001193929 NM_031372 NP_112740 NR_003249 NM_005463
Function Acts as a transcriptional regulator. Promotes transcription repression. Promotes transcription activation in differentiated myotubes (By similarity). Binds to double- and single-stranded DNA sequences. Binds to the transcription suppressor CATR sequence of the COX5B promoter (By similarity). Binds with high affinity to RNA molecules that contain AU-rich elements (AREs) found within the 3'-UTR of many proto-oncogenes and cytokine mRNAs. Binds both to nuclear and cytoplasmic poly(A) mRNAs. Binds to poly(G) and poly(A), but not to poly(U) or poly(C) RNA homopolymers. Binds to the 5'-ACUAGC-3' RNA consensus sequence. {ECO:0000250, ECO:0000269|PubMed:9538234}.
Subcellular Location Nucleus. Cytoplasm. Note=Shuttles between the nucleus and the cytoplasm in a TNPO1-dependent manner.
Tissue Specificity Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney, pancreas, spleen, thymus, prostate, testis, ovary, small intestine, colon and leukocytes. Expressed in myeloid leukemia, gastric adenocarcinoma, cervical carcinoma, hepatoma, fibrosarcoma, colon adenocarcinoma, epidermoid carcinoma, osteosarcoma and urinary bladder carcinoma cells. {ECO:0000269|PubMed:10072754, ECO:0000269|PubMed:9538234}.

JKTBP (E-14) - sc-103577 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
JKTBP (E-14): sc-103577. Western blot analysis of JKTBP expression in MCF7 (A) and Jurkat (B) nuclear extracts.

JKTBP (K-13) - sc-103578 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

JKTBP (G-24) - sc-133699 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Rabbit
Clonality Polyclonal
JKTBP (G-24): sc-133699. Western blot analysis of JKTBP expression in Daudi whole cell lysate.

Anti-HNRNPDL / hnRNP D Antibody (aa214-244, AP) - LS-C259806 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HNRNPDL / hnRNP D Antibody (aa214-244, APC) - LS-C259807 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HNRNPDL / hnRNP D Antibody (aa214-244, Biotin) - LS-C259808 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HNRNPDL / hnRNP D Antibody (aa214-244, PE) - LS-C259811 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HNRNPDL / hnRNP D Antibody (aa214-244, FITC) - LS-C259809 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HNRNPDL / hnRNP D Antibody (aa214-244, Azide-free, HRP) - LS-C259810 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HNRNPDL / hnRNP D Antibody (aa214-244) - LS-C329639 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-HNRNPDL / hnRNP D Antibody (aa241-290) - LS-C199073 from LifeSpan Bioscience

Prices $315.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
IHC of paraffin-embedded human lung carcinoma tissue, using HNRPDL Antibody. The sample on the right was incubated with synthetic peptide.

Anti-HNRNPDL / hnRNP D Antibody (C-Terminus) - LS-C101856 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
HNRPDL antibody LS-C101856 Western blot of MCF7 cell lysate.

Anti-HNRNPDL / hnRNP D Antibody (aa206-234) - LS-C164963 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
HNRPDL Antibody western blot of K562,HepG2,Jurkat cell line lysates (35 ug/lane). The HNRPDL antibody detected the HNRPDL protein (arrow).

Anti-HNRNPDL / hnRNP D Antibody (aa119-168) - LS-C31582 from LifeSpan Bioscience

Prices $325.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
HNRPDL antibody LS-C31582 IHC of formalin-fixed, paraffin-embedded human Muscle. Positive label: Skeletal muscle cells indicated with arrows. Antibody concentration 4-8 ug/ml. Magnification 400X.

HNRPDL Antibody - NBP1-57156 from Novus Biologicals

Prices $299.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HNRPDL Antibody - NBP2-38806 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HNRPDL Antibody [NBP2-38806] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Human cell line RT-4. Lane 3: Human cell line U-251MG. Lane 4: Human Plasma. Lane 5: Human liver tissue. Lane 6: Human tonsil tissue

HNRPDL Antibody - NBP1-57157 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: HNRPDL Antibody [NBP1-57157] - MCF-7 whole cell lysates, concentration 0.2-1 ug/ml.

HNRPDL Antibody - NBP2-38017 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

Anti-HNRPDL antibody produced in rabbit - SAB4503750 from Sigma-Aldrich

Prices $335.50
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HNRPDL: <B>Cat. No. SAB4503750</B>: Immunohistochemistry analysis of paraffin-embedded human lung carcinoma tissue using Anti-HNRPDL antibody. Cells on the left were treated with the Anti-HNRPDL antibody. Cells on the right (negative control) were treated with both Anti-HNRPDL antibody and the synthesized immunogen peptide.

Anti-HNRPDL antibody produced in rabbit - SAB2101058 from Sigma-Aldrich

Prices $347.50
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-HNRPDL: <B>Cat. No.SAB2101058</B>: HNRPDL in MCF7 cell lysate with HNRPDL antibody at 1.0 μg/mL.

Anti-HNRPDL antibody produced in rabbit - AV40585 from Sigma-Aldrich

Prices $267.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-HNRPDL: <B>Cat. No. AV40585</B>: Immunohistochemistry of HNRPDL in Human Muscle tissue with HNRPDL antibody at 4-8 μg/mL.

HNRPDL antibody - middle region (ARP40585_T100) - ARP40585_T100 from Aviva Systems Biology

Prices $229.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HNRPDL antibody - C-terminal region (ARP40586_P050) - ARP40586_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HNRDL Antibody - middle region (ARP75318_P050) - ARP75318_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

HNRDL Antibody - C-terminal region (ARP75319_P050) - ARP75319_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
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