GRHL1

Gene Symbol GRHL1
Entrez Gene 29841
Alt Symbol LBP32, MGR, NH32, TFCP2L2
Species Human
Gene Type protein-coding
Description grainyhead-like 1 (Drosophila)
Other Description LBP protein 32|grainyhead-like protein 1 homolog|mammalian grainyhead|transcription factor CP2-like 2|transcription factor LBP-32
Swissprots Q6NWN9 Q6NWN7 B5MEC2 A6NLA4 Q9NZI5 Q6NWN8 Q8NI33 Q53T93 B2R7E4
Accessions AAX93273 EAX00973 Q9NZI5 AA234992 AF198489 AAF32276 AF411210 AAM22616 AI686262 AK293855 BAH11612 AK296982 BAG59523 AK312950 BAG35791 BC063299 BC067519 AAH67519 BC067520 AAH67520 BC067521 AAH67521 BC098456 BE537504 BF573452 CB048030 CB960104 CD559574 DA860769 XM_005246159 XP_005246216 XM_006711882 XP_006711945 XM_006711884 XP_006711947 XM_011510343 XP_011508645 XM_011510344 XP_011508646 NM_198182 NP_937825
Function Transcription factor involved in epithelial development. Binds directly to the consensus DNA sequence 5'-AACCGGTT-3' (PubMed:12175488, PubMed:18288204). Important regulator of DSG1 in the context of hair anchorage and epidermal differentiation, participates in the maintenance of the skin barrier. There is no genetic interaction with GRHL3, no functional cooperativity due to diverse target gene selectivity during epithelia development (By similarity). Isoform 1 may function as an activator and isoform 2 as a repressor in tissues where both forms are expressed (PubMed:12175488). {ECO:0000250|UniProtKB:Q921D9, ECO:0000269|PubMed:12175488, ECO:0000269|PubMed:18288204}.
Subcellular Location Nucleus {ECO:0000269|PubMed:18288204}.
Tissue Specificity Isoform 1 is highly expressed in brain, pancreas, tonsil, placenta and kidney. Isoform 2 is highly expressed in brain and liver. Expressed at very low levels in non- steroidogenic cells. {ECO:0000269|PubMed:10644752, ECO:0000269|PubMed:12175488}.

GRHL1 (E-14) - sc-168034 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

GRHL1 (S-12) - sc-168035 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-Grainyhead-like protein 1 homolog antibody - ab77762 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-Grainyhead-like protein 1 homolog antibody (ab77762) at 1 µg/mlLane 1 : JEG-3 (Human placental choriocarcinoma cell line) Whole Cell LysateLane 2 : HepG2 (Human hepatocellular liver carcinoma cell line) Whole Cell Lysate Lane 3 : HEK293 (Human embryonic kidney cell line) Whole Cell Lysate Lane 4 : Jurkat (Human T cell lymphoblast-like cell line) Whole Cell LysateLysates/proteins at 10 µg per lane.SecondaryGoat polyclonal to Rabbit IgG - H&L - Pre-Adsorbed (HRP) at 1/3000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.

Anti-Grainyhead-like protein 1 homolog antibody - ab111582 from Abcam

Prices $370.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Anti-Grainyhead-like protein 1 homolog antibody (ab111582) at 1/1000 dilution + NT2D1 whole cell lysate at 30 µg

Anti-Grainyhead-like protein 1 homolog antibody - ab85193 from Abcam

Prices $370.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-Grainyhead-like protein 1 homolog antibody (ab85193) at 1 µg/ml (in 5% skim milk / PBS buffer) + Jurkat cell lysate at 10 µgSecondaryHRP conjugated anti-Rabbit IgG at 1/50000 dilution

Anti-Grainyhead-like protein 1 homolog antibody - ab129508 from Abcam

Prices $370.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-Grainyhead-like protein 1 homolog antibody (ab129508) at 1/100 dilution + HepG2 cell line lysates at 35 µg

Anti-GRHL1 / TFCP2L2 Antibody (aa294-322, AP) - LS-C235970 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRHL1 / TFCP2L2 Antibody (aa294-322, APC) - LS-C235971 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRHL1 / TFCP2L2 Antibody (aa294-322, Biotin) - LS-C235972 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRHL1 / TFCP2L2 Antibody (aa294-322, PE) - LS-C235975 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRHL1 / TFCP2L2 Antibody (aa294-322, FITC) - LS-C235973 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRHL1 / TFCP2L2 Antibody (aa294-322, Azide-free, HRP) - LS-C249134 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRHL1 / TFCP2L2 Antibody (aa293-322) - LS-C321781 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-GRHL1 / TFCP2L2 Antibody (aa294-322) - LS-C166666 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
GRHL1 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The GRHL1 antibody detected the GRHL1 protein (arrow).

Anti-GRHL1 / TFCP2L2 Antibody (aa108-157) - LS-C101366 from LifeSpan Bioscience

Prices $365.00
Sizes 50 µg
Host Rabbit
Clonality Polyclonal
GRHL1 antibody LS-C101366 Western blot of Jurkat lysate.

Anti-GRHL1 / TFCP2L2 Antibody (C-Terminus) - LS-C201283 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal
Western blot of Human Lung tumor. GRHL1 antibody dilution 1.0 ug/ml.

GRHL1 Antibody - NBP1-81321 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GRHL1 Antibody [NBP1-81321] - Analysis in mouse cell line NIH-3T3 and rat cell line NBT-II.

GRHL1 Antibody - NBP1-81322 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GRHL1 Antibody [NBP1-81322] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10. Lane 2: Negative control (vector only transfected HEK293T lysate). Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (3.1 kDa) in mammalian HEK293T cells).

GRHL1 Antibody - NBP2-16744 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GRHL1 Antibody [NBP2-16744] - Sample (30 ug of whole cell lysate) A: NT2D1 7. 5% SDS PAGE gel, diluted at 1:1000.

GRHL1 Antibody - NBP2-16743 from Novus Biologicals

Prices $329.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Western Blot: GRHL1 Antibody [NBP2-16743] - Sample (30 ug of whole cell lysate) A: NT2D1 B: IMR32 7. 5% SDS PAGE gel, diluted at 1:2000.

Anti-GRHL1 antibody produced in rabbit - HPA005798 from Sigma-Aldrich

Prices $429.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunohistochemistry</B><BR/>Anti-GRHL1: <B>Cat. No. HPA005798</B>: Immunoperoxidase staining of formalin-fixed, paraffin-embedded human esophageal tissue showing nuclear staining of squamous epithelial cells.

Anti-GRHL1 antibody produced in rabbit - SAB2100971 from Sigma-Aldrich

Prices $347.50
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Anti-GRHL1: <B>Cat. No.SAB2100971</B>: GRHL1 in Jurkat cell lysate with GRHL1 antibody at 1.0 μg/mL.

GRHL1 antibody - N-terminal region (ARP31917_P050) - ARP31917_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GRHL2 Antibody - C-terminal region (ARP33606_P050) - ARP33606_P050 from Aviva Systems Biology

Prices $289.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal

GRHL1-Antibody-Center - AP16357c from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
GRHL1 Antibody (Center) (Cat. #AP16357c) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the GRHL1 antibody detected the GRHL1 protein (arrow).
Search more