GRHL1

Gene Symbol GRHL1
Entrez Gene 29841
Alt Symbol LBP32, MGR, NH32, TFCP2L2
Species Human
Gene Type protein-coding
Description grainyhead-like 1 (Drosophila)
Other Description LBP protein 32|grainyhead-like protein 1 homolog|mammalian grainyhead|transcription factor CP2-like 2|transcription factor LBP-32
Swissprots Q6NWN9 Q6NWN7 B5MEC2 A6NLA4 Q9NZI5 Q6NWN8 Q8NI33 Q53T93 B2R7E4
Accessions AAX93273 EAX00973 Q9NZI5 AA234992 AF198489 AAF32276 AF411210 AAM22616 AI686262 AK293855 BAH11612 AK296982 BAG59523 AK312950 BAG35791 BC063299 BC067519 AAH67519 BC067520 AAH67520 BC067521 AAH67521 BC098456 BE537504 BF573452 CB048030 CB960104 CD559574 DA860769 XM_005246159 XP_005246216 XM_006711882 XP_006711945 XM_006711884 XP_006711947 XM_011510343 XP_011508645 XM_011510344 XP_011508646 NM_198182 NP_937825
Function Transcription factor involved in epithelial development. Binds directly to the consensus DNA sequence 5'-AACCGGTT-3' (PubMed:12175488, PubMed:18288204). Important regulator of DSG1 in the context of hair anchorage and epidermal differentiation, participates in the maintenance of the skin barrier. There is no genetic interaction with GRHL3, no functional cooperativity due to diverse target gene selectivity during epithelia development (By similarity). Isoform 1 may function as an activator and isoform 2 as a repressor in tissues where both forms are expressed (PubMed:12175488). {ECO:0000250|UniProtKB:Q921D9, ECO:0000269|PubMed:12175488, ECO:0000269|PubMed:18288204}.
Subcellular Location Nucleus {ECO:0000269|PubMed:18288204}.
Tissue Specificity Isoform 1 is highly expressed in brain, pancreas, tonsil, placenta and kidney. Isoform 2 is highly expressed in brain and liver. Expressed at very low levels in non- steroidogenic cells. {ECO:0000269|PubMed:10644752, ECO:0000269|PubMed:12175488}.

Human Grainyhead-like protein 1 homolog full length protein - ab162241 from Abcam

Category Protein
Source Wheat germ
Species Human
ab162241 on a 12.5% SDS-PAGE stained with Coomassie Blue.

GRHL1 / TFCP2L2 Antibody Blocking Peptide - LS-E4117 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

GRHL1 / TFCP2L2 Antibody Blocking Peptide - LS-E11136 from LifeSpan Bioscience

Category Peptide
Prices $145.00
Sizes 100 µg

Recombinant Human GRHL1 Protein - H00029841-P01 from Novus Biologicals

Category Protein
Prices $319.00
Sizes 2 µg
Source Wheat Germ
Species Human

GRHL1-Antibody-Center-Blocking-Peptide - BP16357c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

GRHL1 / LBP32 - H00029841-P01 from Acris Antibodies

Category Protein
Prices $310.00
Sizes 2 µg
Species Human

GRHL1 fusion protein - ag11832 from Proteintech Group

Category Protein
Source E. coli-derived, PGEX-4T
Species Human

GRHL1 fusion protein - ag12063 from Proteintech Group

Category Protein
Source E. coli-derived, PET28a
Species Human

Recombinant Human Grainyhead-like protein 1 homolog(GRHL1) - CSB-YP868368HU CSB-EP868368HU CSB-BP868368HU CSB-MP868368HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

GRHL1 / LBP32 - TP329312 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
GRHL1 / LBP32

GRHL1 Recombinant Protein Antigen - NBP1-81322PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

GRHL1 Recombinant Protein Antigen - NBP1-81321PEP from Novus Biologicals

Category Protein
Prices $199.00
Sizes 100 µl
Source E.coli
Species Human

GRHL1 Peptide, Human - M34GP06642H from Creative Peptides

Category Peptide
Source Synthetic.
Species Human

Grainyhead-like protein 1 homolog (GRHL1), Recombinant Protein - MBS1411803 from MyBioSource

Category Protein
Prices $1,415.00, $1,415.00, $1,640.00, $1,640.00, $2,385.00, $2,385.00, $2,830.00, $2,830.00
Sizes 500 µg (E-Coli), 50 µg (Baculovirus), 500 µg (Yeast), 50 µg (Mammalian-Cell), 1 mg (E-Coli), 100 µg (Baculovirus), 1 mg (Yeast), 100 µg (Mammalian-Cell)
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human
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