Gene Symbol | CD180 |
---|---|
Entrez Gene | 4064 |
Alt Symbol | LY64, Ly78, RP105 |
Species | Human |
Gene Type | protein-coding |
Description | CD180 molecule |
Other Description | CD180 antigen|lymphocyte antigen 64|lymphocyte antigen-64, radioprotective, 105kDa|radioprotective 105 kDa protein |
Swissprots | Q32MM5 Q99467 B2R7Z7 |
Accessions | EAW51318 Q99467 AK313177 BAG35994 AL544501 AL570708 AW512119 BC109069 AAI09070 BC109070 AAI09071 BP344300 D83597 BAA12019 XM_005248504 XP_005248561 NM_005582 NP_005573 |
Function | May cooperate with MD-1 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS) in B-cells. Leads to NF-kappa-B activation. Also involved in the life/death decision of B-cells (By similarity). {ECO:0000250}. |
Subcellular Location | Cell membrane; Single-pass type I membrane protein. |
Tissue Specificity | Expressed mainly on mature peripherical B cells. Detected in spleen, lymph node and appendix. Not detected in pre-B and -T cells. |
RP105 CRISPR/Cas9 KO Plasmid (h) - sc-409643 from Santa Cruz Biotechnology
|
||||||||
RP105 HDR Plasmid (h) - sc-409643-HDR from Santa Cruz Biotechnology
|
||||||||
RP105 Double Nickase Plasmid (h) - sc-409643-NIC from Santa Cruz Biotechnology
|
||||||||
RP105 Double Nickase Plasmid (h2) - sc-409643-NIC-2 from Santa Cruz Biotechnology
|
||||||||
RP105 CRISPR Activation Plasmid (h) - sc-409643-ACT from Santa Cruz Biotechnology
|
||||||||
RP105 CRISPR Activation Plasmid (h2) - sc-409643-ACT-2 from Santa Cruz Biotechnology
|
||||||||
RP105 Lentiviral Activation Particles (h) - sc-409643-LAC from Santa Cruz Biotechnology
|
||||||||
RP105 Lentiviral Activation Particles (h2) - sc-409643-LAC-2 from Santa Cruz Biotechnology
|
||||||||
RP105 siRNA (h) - sc-72150 from Santa Cruz Biotechnology
|
||||||||
RP105 shRNA Plasmid (h) - sc-72150-SH from Santa Cruz Biotechnology
|
||||||||
RP105 shRNA (h) Lentiviral Particles - sc-72150-V from Santa Cruz Biotechnology
|
||||||||
RP105/CD180 RNAi - H00004064-R02 from Novus Biologicals
|
||||||||
MISSION® esiRNA - EHU047391 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit - CKOZFN5687 from Sigma-Aldrich
|
||||||||
CompoZr® Knockout ZFN Kit, ZFN plasmid only - CKOZFND5687 from Sigma-Aldrich
|
||||||||
MISSION® 3′UTR Lenti GoClone™ - HUTR04796 from Sigma-Aldrich
|
||||||||
CD180 siRNA (Human) - CRH2753 from Cohesion Biosciences
|
||||||||
CD180 - MBS8238195 from MyBioSource
|
||||||||
shRNA set against Human CD180 (NM_005582.2) - SHH258557 from Creative biogene
|
||||||||
shRNA set against Human CD180(NM_005582.2) - SHG155085 from Creative biogene
|
||||||||
CD180 shRNA Plasmid (Human) - CHH2753 from Cohesion Biosciences
|
||||||||
CD180 miRNA 3'UTR clone - MiUTR1H-01843 from Creative biogene
|