PLEKHA8

Gene Symbol PLEKHA8
Entrez Gene 84725
Alt Symbol FAPP2
Species Human
Gene Type protein-coding
Description pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 8
Other Description PH domain-containing family A member 8|phosphatidylinositol-four-phosphate adapter protein 2|phosphoinositol 4-phosphate adapter protein 2|pleckstrin homology domain-containing family A member 8|serologically defined breast cancer antigen NY-BR-86
Swissprots B4DH00 Q9H8Z7 Q96JA3 Q9H274 Q9BU78 Q7Z5V8
Accessions EAW93930 EAW93931 EAW93932 EAW93933 Q96JA3 AB073667 AF308300 AAG48267 AI168153 AI954066 AK023180 BAB14449 AK294857 BAG57961 AL832700 BC002838 AAH02838 BC053990 AAH53990 CR627312 DQ893498 ABM84424 DQ896458 ABM87457 XM_005249897 XP_005249954 XM_005249898 XP_005249955 XM_011515591 XP_011513893 XM_011515592 XP_011513894 XM_011515593 XP_011513895 XM_011515594 XP_011513896 XM_011515595 XP_011513897 XM_011515596 XP_011513898 NM_001197026 NP_001183955 NM_001197027 NP_001183956 NM_032639 NP_116028
Function Cargo transport protein that is required for apical transport from the Golgi complex. Transports AQP2 from the trans- Golgi network (TGN) to sites of AQP2 phosphorylation. Mediates the non-vesicular transport of glucosylceramide (GlcCer) from the trans-Golgi network (TGN) to the plasma membrane and plays a pivotal role in the synthesis of complex glycosphingolipids. Binding of both phosphatidylinositol 4-phosphate (PIP) and ARF1 are essential for the GlcCer transfer ability. Also required for primary cilium formation, possibly by being involved in the transport of raft lipids to the apical membrane, and for membrane tubulation. {ECO:0000269|PubMed:15107860, ECO:0000269|PubMed:16103222, ECO:0000269|PubMed:17687330}.
Subcellular Location Cytoplasm. Golgi apparatus, trans-Golgi network membrane. Membrane; Peripheral membrane protein. Note=Mainly localized to the trans-Golgi network (TGN) but also found at the rims of Golgi cisternae. Associates with ARF1 at Golgi apparatus membranes.
Tissue Specificity Expressed in kidney cell lines. {ECO:0000269|PubMed:15107860}.

FAPP2 (N-14) - sc-162817 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal

Anti-FAPP2 antibody - ab124480 from Abcam

Prices $376.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
All lanes : Anti-FAPP2 antibody (ab124480) at 1/1000 dilutionLane 1 : Human fetal liver lysateLane 2 : Human fetal heart lysateLane 3 : Human fetal kidney lysate

Anti-FAPP2 antibody - ab38748 from Abcam

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
ab38748 staining FAPP2 in Human placenta tissue at 2 µg/ml by Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections). Steamed antigen retrieval with citrate buffer pH 6 was performed. Detected with AP-Staining.

Anti-FAPP2 antibody - C-terminal - ab173904 from Abcam

Prices $376.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
Anti-FAPP2 antibody - C-terminal (ab173904) at 1/100 dilution + HepG2 cell lysate at 35 µg

Anti-PLEKHA8 Antibody (aa428-440) IHC-plus™ - LS-B2332 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µg
Host Goat
Clonality Polyclonal
Anti-PLEKHA8 antibody IHC of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody LS-B2332 concentration 5 ug/ml.

Anti-PLEKHA8 Antibody (aa456-482, APC) - LS-C266524 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHA8 Antibody (aa456-482, AP) - LS-C266525 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHA8 Antibody (aa456-482, Biotin) - LS-C266526 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHA8 Antibody (aa456-482, FITC) - LS-C266527 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHA8 Antibody (aa456-482, PE) - LS-C266530 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHA8 Antibody (aa456-482, Azide-free, HRP) - LS-C266528 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHA8 Antibody - LS-C307478 from LifeSpan Bioscience

Prices $455.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal

Anti-PLEKHA8 Antibody (aa455-482) - LS-C324100 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PLEKHA8 Antibody (aa456-482) - LS-C158679 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
PLEKHA8 Antibody western blot of HepG2 cell line lysates (35 ug/lane). The PLEKHA8 antibody detected the PLEKHA8 protein (arrow).

Anti-PLEKHA8 Antibody (aa122-400) IHC-plus™ - LS-B12163 from LifeSpan Bioscience

Prices $395.00
Sizes 50 µl
Host Rabbit
Clonality Polyclonal
Human Uterus, Endometrium: Formalin-Fixed, Paraffin-Embedded (FFPE)

FAPP2 Antibody - NB300-834 from Novus Biologicals

Prices $299.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

FAPP2 Antibody - H00084725-D01P from Novus Biologicals

Prices $399.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Western Blot: FAPP2 Antibody [H00084725-D01P] - Analysis of PLEKHA8 expression in transfected 293T cell line by PLEKHA8 polyclonal antibody.Lane 1: PLEKHA8 transfected lysate(49.50 KDa).Lane 2: Non-transfected lysate.

FAPP2 Antibody - H00084725-B01P from Novus Biologicals

Prices $359.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
Western Blot: FAPP2 Antibody [H00084725-B01P] - Analysis of PLEKHA8 expression in HeLa.

Anti-FAPP2/PLEKHA8 antibody produced in goat - SAB2500383 from Sigma-Aldrich

Prices $376.00
Sizes 100 µg
Host Goat
Clonality Polyclonal

Anti-PLEKHA8 antibody produced in rabbit - SAB1401899 from Sigma-Aldrich

Prices $347.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-PLEKHA8, antibody produced in rabbit, purified immunoglobulin: <B>Cat. No. SAB1401899</B>: Antibody concentration: 0.1 - 5.0 μg/mL. Specific band of ~49.50 kDa using PLEKHA8 transfected 293T lysate.<BR/><B>Lanes</B><BR/>1. Transfected 293T lysate.<BR/>2. Non-transfected 293T lysate.

Anti-PLEKHA8 antibody produced in mouse - SAB1401898 from Sigma-Aldrich

Prices $347.00
Sizes 50 µg
Host Mouse
Clonality Polyclonal
<B>Immunoblotting</B><BR/>Polyclonal Anti-PLEKHA8, antibody produced in mouse, purified immunoglobulin: <B>Cat. No. SAB1401898</B>: Antibody concentration: 1.0 - 5.0 μg/mL. Specific band of ~49.46 kDa using HeLa lysate.

PLEKHA8-Antibody-C-term - AP18305b from Abgent, a WuXi AppTec company

Prices $99.00, $295.00
Sizes 80 µl, 400 µl
Host Rabbit
Clonality Polyclonal
PLEKHA8 Antibody (C-term) (Cat. #AP18305b) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the PLEKHA8 antibody detected the PLEKHA8 protein (arrow).

FAPP2--PLEKHA8-Antibody - AF1400a from Abgent, a WuXi AppTec company

Prices $335.00
Sizes 100 µg
Host Goat
Clonality Polyclonal
AF1400a (2.5 µg/ml) staining of paraffin embedded Human Placenta. Steamed antigen retrieval with citrate buffer pH 6, AP-staining.

FAPP2 / PLEKHA8 antibody, C-term - GTX89754 from GeneTex

Prices $319.00
Sizes 100 μg
Host Goat
Clonality Polyclonal
Anti-FAPP2 / PLEKHA8 antibody, C-term used in IHC (Formalin-fixed paraffin-embedded sections). GTX89754

PLEKHA8 Antibody - C-terminal region (OAAB13834) - OAAB13834 from Aviva Systems Biology

Prices $289.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
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