TPP1

Gene Symbol	TPP1
Entrez Gene	1200
Alt Symbol	CLN2, GIG1, LPIC, SCAR7, TPP-1
Species	Human
Gene Type	protein-coding
Description	tripeptidyl peptidase I
Other Description	cell growth-inhibiting gene 1 protein|growth-inhibiting protein 1|lysosomal pepstatin insensitive protease|tripeptidyl aminopeptidase|tripeptidyl-peptidase 1
Swissprots	Q71JP6 Q5JAK6 Q96C37 O14773 Q6UX56 Q53HT1
Accessions	AAC98480 CAH05560 EAW68685 EAW68686 O14773 AF017456 AAB80725 AI023962 AK222499 BAD96219 AK222538 BAD96258 AK293518 BAG57000 AK293741 BAG57164 AK295801 BAG58620 AK299703 BAG61604 AK300998 BAG62617 AK303323 BAG64389 AK312388 BAG35305 AY268890 AAQ72732 AY358502 AAQ88866 BC014863 AAH14863 BP279860 BP287220 DQ891682 ABM82608 DQ894867 ABM85793 NM_000391 NP_000382
Function	Lysosomal serine protease with tripeptidyl-peptidase I activity. May act as a non-specific lysosomal peptidase which generates tripeptides from the breakdown products produced by lysosomal proteinases. Requires substrates with an unsubstituted N-terminus (By similarity). {ECO:0000250}.
Subcellular Location	Lysosome. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV.
Tissue Specificity	Detected in all tissues examined with highest levels in heart and placenta and relatively similar levels in other tissues.
Top Pathways	Lysosome

• Antibodies
• Assays/Kits
• Proteins/Peptides
• siRNAs/Functional Genomics
• cDNA Clones
• Cell/Tissue/Blood Products

Human-TPP1-cDNA-Clone - DC03944 from Abgent, a WuXi AppTec company Prices $760.05 Sizes 10 µg Species Human Accession BC014863

TPP1 - MBS1276576 from MyBioSource Prices $175.00 Sizes 10ug plasmid + 200ul glycerol stock Species Human Accession BC014863

Human TPP1 cDNA clone(NM_000391.3) - CDFH020219 from Creative Biomart Species Human Accession NM_000391.3

Human TPP1 ORF Clone(NM_000391.3) - CDCR336089 from Creative Biomart Species Human Accession NM_000391.3

Human TPP1 ORF Clone(NM_000391.3) - CDCR336091 from Creative Biomart Species Human Accession NM_000391.3

Human TPP1 ORF Clone(NM_000391.3) - CDCR336097 from Creative Biomart Species Human Accession NM_000391.3

Human TPP1 ORF Clone(NM_000391.3) - CDCL179442 from Creative Biomart Species Human Accession NM_000391.3

human TPP1 ORF clone - CDCH094330 from Creative Biomart Species Human Accession NM_000391

human TPP1 ORF clone - CDCH094331 from Creative Biomart Species Human Accession NM_000391

human TPP1 ORF clone - CDCH094332 from Creative Biomart Species Human Accession NM_000391

human TPP1 ORF clone - CDCH094333 from Creative Biomart Species Human Accession NM_000391

Human TPP1 Gene cDNA clone plasmid - HG13619-G from Sino Biological Species Human

Human CLN2 Gene ORF cDNA clone expression plasmid, C-Flag tag - HG13619-CF from Sino Biological Species Human

Human CLN2 Gene ORF cDNA clone expression plasmid, C-Myc tag - HG13619-CM from Sino Biological Species Human

Human CLN2 Gene ORF cDNA clone expression plasmid, N-His tag - HG13619-NH from Sino Biological Species Human

Human CLN2 Gene ORF cDNA clone expression plasmid, C-HA tag - HG13619-CY from Sino Biological Species Human

Human CLN2 Gene ORF cDNA clone expression plasmid, C-His tag - HG13619-CH from Sino Biological Species Human

Human CLN2 Gene ORF cDNA clone expression plasmid - HG13619-UT from Sino Biological Species Human

Human CLN2 Gene ORF cDNA clone expression plasmid, N-HA tag - HG13619-NY from Sino Biological Species Human

Human CLN2 Gene ORF cDNA clone expression plasmid, C-OFPSpark tag - HG13619-ACR from Sino Biological Species Human

Human CLN2 Gene ORF cDNA clone expression plasmid, C-GFPSpark tag - HG13619-ACG from Sino Biological Species Human

Human CLN2 Gene ORF cDNA clone expression plasmid, N-Flag tag - HG13619-NF from Sino Biological Species Human

Human CLN2 Gene ORF cDNA clone expression plasmid, N-Myc tag - HG13619-NM from Sino Biological Species Human

human TPP1 ORF clone (NM_000391.3) - CDCH094330 from Creative biogene Species Human

Human TPP1 ORF Clone (BC014863) - CDCS405632 from Creative biogene Species Human Accession O14773

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