PRDM2

Gene Symbol PRDM2
Entrez Gene 7799
Alt Symbol HUMHOXY1, KMT8, MTB-ZF, RIZ, RIZ1, RIZ2
Species Human
Gene Type protein-coding
Description PR domain containing 2, with ZNF domain
Other Description GATA-3 binding protein G3B|GATA-3-binding protein G3B|MTE-binding protein|PR domain zinc finger protein 2|PR domain-containing protein 2|lysine N-methyltransferase 8|retinoblastoma protein-binding zinc finger protein|retinoblastoma protein-interacting zinc finger protein|zinc finger protein RIZ|zinc-finger DNA-binding protein
Swissprots Q13029 B1AJZ4 Q5VUL9 Q5THJ1 B5MC68 Q14550 Q13149
Accessions EAW51695 EAW51696 EAW51697 EAW51698 Q13029 AB208877 BAD92114 AI651991 AK123605 AK124197 AK293725 BAG57154 AK300441 BAG62164 AK307377 AK308135 AK311678 AW444997 BC014468 BC032768 BC140012 BC172414 AAI72414 BF378912 BM008289 BU621515 BX647310 D45132 BAA08110 U17838 AAC50820 U23736 AAA87023 XM_005245998 XP_005246055 XM_011542092 XP_011540394 XM_011542093 XP_011540395 NM_001007257 NP_001007258 NM_001135610 NP_001129082 NM_012231 NP_036363 NM_015866 NP_056950
Function S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene. {ECO:0000269|PubMed:14633678}.
Subcellular Location Nucleus {ECO:0000269|PubMed:14633678, ECO:0000269|PubMed:7538672, ECO:0000269|PubMed:9006946}.
Tissue Specificity Highly expressed in retinoblastoma cell lines and in brain tumors. Also expressed in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. Isoform 1 is expressed in testis at much higher level than isoform 3. {ECO:0000269|PubMed:8654390, ECO:0000269|PubMed:9006946}.

RIZ (N-20) - sc-14228 from Santa Cruz Biotechnology

Prices $279.00
Sizes 200 µg/ml
Host Goat
Clonality Polyclonal
RIZ (N-20): sc-14228. Western blot analysis of RIZ expression in non-transfected: sc-117752 (A) and human RIZ transfected: sc-372474 (B) 293T whole cell lysates.

RIZ (33AT1045) - sc-130256 from Santa Cruz Biotechnology

Prices $279.00
Sizes 100 µg/ml
Host Mouse
Clonality Monoclonal

Anti-KMT8/Riz1/Riz2 antibody - ab3790 from Abcam

Prices $359.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Rat B50 brain tumor cell extracts were immunoprecipitated with RIZ antibody or preimmune (Liu L. et al. J. Biol. Chem. 1997. 272: 2984.).

Anti-RIZ1 antibody - ab9710 from Abcam

Prices $370.00
Sizes 100 µg
Host Rabbit
Clonality Polyclonal
Anti-RIZ1 antibody (ab9710) at 1/1000 dilutionSecondaryGoat anti-Rabbit at 1/25000 dilutiondeveloped using the ECL techniquePerformed under reducing conditions.Exposure time :  1 minuteKaren Halls, University of Cambridge

Anti-RIZ1 antibody [33AT1045] - ab3791 from Abcam

Prices $370.00
Sizes 400 µl
Host Mouse
Clonality Monoclonal
Clone 33AT1045

Anti-RIZ1 antibody - N-terminal - ab198792 from Abcam

Prices $376.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Anti-RIZ1 antibody - N-terminal (ab198792) at 1/200 dilution + MCF-7 cell lysate at 40 µg

Anti-PRDM2 / RIZ1 Antibody (aa1098-1115) - LS-C148877 from LifeSpan Bioscience

Host Rabbit
Clonality Polyclonal

Anti-PRDM2 / RIZ1 Antibody (aa1-347, clone 33AT1045, AP) - LS-C250389 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 33AT1045

Anti-PRDM2 / RIZ1 Antibody (aa1-347, clone 33AT1045, APC) - LS-C250390 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 33AT1045

Anti-PRDM2 / RIZ1 Antibody (aa1-347, clone 33AT1045, Biotin) - LS-C250392 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 33AT1045

Anti-PRDM2 / RIZ1 Antibody (aa1-347, clone 33AT1045, FITC) - LS-C250393 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 33AT1045

Anti-PRDM2 / RIZ1 Antibody (aa1-347, clone 33AT1045, Azide-free, HRP) - LS-C250394 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 33AT1045

Anti-PRDM2 / RIZ1 Antibody (aa1-347, clone 33AT1045, PE) - LS-C250395 from LifeSpan Bioscience

Prices $545.00
Sizes 100 µl
Host Mouse
Clonality Monoclonal
Clone 33AT1045

Anti-PRDM2 / RIZ1 Antibody (aa245-573, AP) - LS-C267063 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM2 / RIZ1 Antibody (aa245-573, APC) - LS-C267064 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM2 / RIZ1 Antibody (aa245-573, PE) - LS-C267068 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM2 / RIZ1 Antibody (aa245-573, FITC) - LS-C267066 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM2 / RIZ1 Antibody (aa245-573, Azide-free, HRP) - LS-C267067 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM2 / RIZ1 Antibody (aa245-573, Biotin) - LS-C267065 from LifeSpan Bioscience

Prices $545.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM2 / RIZ1 Antibody (aa1-347, clone 33AT1045) - LS-C319195 from LifeSpan Bioscience

Prices $435.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone 33AT1045

Anti-PRDM2 / RIZ1 Antibody (aa245-573) - LS-C324276 from LifeSpan Bioscience

Prices $345.00
Sizes 200 µl
Host Rabbit
Clonality Polyclonal

Anti-PRDM2 / RIZ1 Antibody (clone RIZ1723) - LS-C179711 from LifeSpan Bioscience

Prices $370.00
Sizes 100 µg
Host Mouse
Clonality Monoclonal
Clone RIZ1723

Anti-PRDM2 / RIZ1 Antibody - LS-C98738 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Rabbit
Clonality Polyclonal
A) Rat B50 brain tumor cell extracts were immunoprecipitated with RIZ1 antibody or preimmune (ref.9). B)Immunohistochemical of RIZ1 in adenovirus-transduced tumor cells. Established HCT116 xenograft tumors at day 2 after infection of AdRIZ1, Adnull, or buffer alone were processed for RIZ1 in situ detection (TUNEL) analysis (ref.10).

Anti-PRDM2 / RIZ1 Antibody (clone 33AT1045) - LS-C96458 from LifeSpan Bioscience

Prices $295.00
Sizes 400 µl
Host Mouse
Clonality Monoclonal
Clone 33AT1045
Western blot of anti-PRDM2 antibody in lysate from PRDM2 transgenic lysate.Secondary HRP-anti-mouse was used for signal visualization with chemiluminescence.

RIZ1 Antibody - NBP1-89644 from Novus Biologicals

Prices $419.00
Sizes 100 µl
Host Rabbit
Clonality Polyclonal
Immunocytochemistry/Immunofluorescence: RIZ1 Antibody [NBP1-89644] - Staining of human cell line U-251MG shows positivity in nucleus and golgi apparatus.
Search more