PRDM2

Gene Symbol PRDM2
Entrez Gene 7799
Alt Symbol HUMHOXY1, KMT8, MTB-ZF, RIZ, RIZ1, RIZ2
Species Human
Gene Type protein-coding
Description PR domain containing 2, with ZNF domain
Other Description GATA-3 binding protein G3B|GATA-3-binding protein G3B|MTE-binding protein|PR domain zinc finger protein 2|PR domain-containing protein 2|lysine N-methyltransferase 8|retinoblastoma protein-binding zinc finger protein|retinoblastoma protein-interacting zinc finger protein|zinc finger protein RIZ|zinc-finger DNA-binding protein
Swissprots Q13029 B1AJZ4 Q5VUL9 Q5THJ1 B5MC68 Q14550 Q13149
Accessions EAW51695 EAW51696 EAW51697 EAW51698 Q13029 AB208877 BAD92114 AI651991 AK123605 AK124197 AK293725 BAG57154 AK300441 BAG62164 AK307377 AK308135 AK311678 AW444997 BC014468 BC032768 BC140012 BC172414 AAI72414 BF378912 BM008289 BU621515 BX647310 D45132 BAA08110 U17838 AAC50820 U23736 AAA87023 XM_005245998 XP_005246055 XM_011542092 XP_011540394 XM_011542093 XP_011540395 NM_001007257 NP_001007258 NM_001135610 NP_001129082 NM_012231 NP_036363 NM_015866 NP_056950
Function S-adenosyl-L-methionine-dependent histone methyltransferase that specifically methylates 'Lys-9' of histone H3. May function as a DNA-binding transcription factor. Binds to the macrophage-specific TPA-responsive element (MTE) of the HMOX1 (heme oxygenase 1) gene and may act as a transcriptional activator of this gene. {ECO:0000269|PubMed:14633678}.
Subcellular Location Nucleus {ECO:0000269|PubMed:14633678, ECO:0000269|PubMed:7538672, ECO:0000269|PubMed:9006946}.
Tissue Specificity Highly expressed in retinoblastoma cell lines and in brain tumors. Also expressed in a number of other cell lines and in brain, heart, skeletal muscle, liver and spleen. Isoform 1 is expressed in testis at much higher level than isoform 3. {ECO:0000269|PubMed:8654390, ECO:0000269|PubMed:9006946}.

Active human RIZ1 protein fragment - ab79913 from Abcam

Category Protein
Prices $492.00
Sizes 200 µg
Source E. coli
Species Human
Image showing specific activity of ab79913.

Human RIZ1 peptide - ab23566 from Abcam

Category Peptide
All lanes : Anti-RIZ1 antibody ( ab9710 ) at 1 µg/ml Lane 1 : MCF7 cells + Gal4 C-terminal tagged PRDM2/Riz1 Lane 2 : MCF7 cells + Gal4 C-terminal tagged PRDM2/Riz1 with Human RIZ1 peptide (ab23566) at 1 µg/ml Secondary Goat Anti-Rabbit IgG H&L (HRP) ( ab6721 ) at 1/5000 dilution Performed under reducing conditions. Observed band size : 47 kDa ( why is the actual band size different from the predicted? ) Exposure time : 30 seconds

Human RIZ1 protein fragment - ab176927 from Abcam

Category Protein
Source E. coli
Species Human
SDS PAGE analysis of ab176927 Lane 1: ab176927 (5 μg) Lane 2: ab176927 (2 μg)

RIZ1 Partial Recombinant Protein - H00007799-Q01 from Novus Biologicals

Category Protein
Prices $369.00
Sizes 10 µg
Species Human

Human PRDM2 GST tag protein - orb83492 from Biorbyt

Category Protein
Prices $400.00, $612.00
Sizes 50 μg, 100 μg
Source E. coli
Species Human
SDS-PAGE analysis of Human PRDM2 GST tag protein

Human PRDM2 protein - orb83500 from Biorbyt

Category Protein
Prices $323.00, $646.00
Sizes 20 μg, 100 μg
Source E. coli
Species Human
SDS-PAGE analysis of Human PRDM2 protein

PRDM2 - H00007799-Q01-10 from Acris Antibodies

Category Protein
Prices $380.00
Sizes 10 µg
Source in vitro transl.
Species Human

PRDM2 - H00007799-Q01-25 from Acris Antibodies

Category Protein
Prices $500.00
Sizes 25 µg
Source in vitro transl.
Species Human

Recombinant RIZ1 protein - 31357 from ActiveMotif

Category Protein
Prices $395.00
Sizes 200 µg
Source E. coli
Species Human
RIZ1 protein gel. RIZ1 run on an SDS-PAGE gel and stained with Coomassie blue.

Recombinant Human PRDM2, GST tagged - PRDM2-3342H from Creative Biomart

Category Protein
Source E. coli
Species Human

Recombinant Human PRDM2, None tagged - PRDM2-3344H from Creative Biomart

Category Protein
Source E. coli
Species Human

Recombinant Human PRDM2 - PRDM2-27746TH from Creative Biomart

Category Protein
Source E. coli

Human PRDM2 / RIZ1 Protein (GST Tag) - 11216-H09E-50 from Sino Biological

Category Protein
Prices $178.00, $298.00
Sizes 50 µg, 100 µg
Source E. coli
Species Human

Human PRDM2 / RIZ1 Protein - 11216-HNCE-100 from Sino Biological

Category Protein
Prices $138.00, $348.00
Sizes 20 µg, 100 µg
Source E. coli
Species Human

Recombinant Human PR domain zinc finger protein 2(PRDM2) ,partial - CSB-YP613379HU CSB-EP613379HU CSB-BP613379HU CSB-MP613379HU from Cusabio

Category Protein
Source Yeast or E.coli or Baculovirus or Mammalian cell
Species Human

RIZ1 (2-200 aa) (GST-tagged), Human recombinant - 7672-50 from Biovision

Category Protein
Prices $115.00
Sizes 50 μg
Source E. coli
Species Human

RIZ1 (2-200 aa) (GST-tagged), Human recombinant - 7672-100 from Biovision

Category Protein
Prices $215.00
Sizes 100 μg
Source E. coli
Species Human

PRDM2 (transcript variant 4) - TP327715 from Acris Antibodies

Category Protein
Prices $680.00
Sizes 20 µg
Source HEK293 cells
Species Human
PRDM2

PR domain zinc finger protein 2 (PRDM2), partial, Recombinant Protein - MBS1288636 from MyBioSource

Category Protein
Source E Coli or Yeast or Baculovirus or Mammalian Cell
Species Human

Recombinant Human PRDM2 / RIZ1 Protein - PKSH031203 from Elabscience

Category Protein
Source E. coli
Species Human

Recombinant Human PRDM2 / RIZ1 Protein (GST tag) - PKSH031204 from Elabscience

Category Protein
Source E. coli
Species Human

Recombinant Human PRDM2 Protein, GST-tagged - PRDM2-172H from Creative Biomart

Category Protein
Source Insect cell
Species Human

RIZ1 Protein - NBP1-89644PEP from Novus Biologicals

Category Protein
Prices $209.00
Sizes 100 µl
Species Human

PRDM2-RIZ1-Antibody-Blocking-peptide - BP1202c from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg

PRDM2-RIZ1-Antibody-N-term-Blocking-peptide - BP1202a from Abgent, a WuXi AppTec company

Category Peptide
Prices $80.00
Sizes 100 µg
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